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View Structure Prediction Details

Protein: POL31
Organism: Saccharomyces cerevisiae
Length: 487 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POL31.

Description E-value Query
Range
Subject
Range
gi|1256943 - gi|1256943|dbj|BAA08859.1| HYS2 [Saccharomyces cerevisiae]
0.0 [1..487] [1..487]
POLD2 - polymerase (DNA directed), delta 2, regulatory subunit 50kDa
gi|123982305, gi... - gi|208965368|dbj|BAG72698.1| polymerase (DNA directed), delta 2, regulatory subunit 50kDa [synthetic...
0.0 [8..486] [2..453]
gi|42744580, gi|... - gi|47086937|ref|NP_998468.1| DNA-directed DNA polymerase delta 2 [Danio rerio], gi|42744580|gb|AAH66...
0.0 [33..486] [30..451]
DPOD2_MOUSE - DNA polymerase delta subunit 2 OS=Mus musculus GN=Pold2 PE=1 SV=2
0.0 [8..485] [2..452]
DPD2_BOVIN, DPOD... - (P49004) DNA polymerase delta subunit 2 (EC 2.7.7.7) (DNA polymerase delta subunit p50), (P49004) DN...
0.0 [8..486] [2..453]
DPOD2_XENLA - DNA polymerase delta subunit 2 OS=Xenopus laevis GN=pold2 PE=2 SV=1
0.0 [24..486] [23..453]
CG12018-PA - This gene is referred to in FlyBase by the symbol Dmel\CG12018 (CG12018, FBgn0027903). It is a prote...
0.0 [30..487] [6..428]
DPOD2_ORYSJ - DNA polymerase delta small subunit OS=Oryza sativa subsp. japonica GN=POLD2 PE=2 SV=1
DPOD2_ORYSA, DPD... - DNA polymerase delta small subunit (EC 2.7.7.7) - Oryza sativa (Rice), (Q9LRE5) DNA polymerase delta...
0.0 [30..486] [5..424]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDALLTKFNE DRSLQDENLS QPRTRVRIVD DNLYNKSNPF QLCYKKRDYG SQYYHIYQYR  60
   61 LKTFRERVLK ECDKRWDAGF TLNGQLVLKK DKVLDIQGNQ PCWCVGSIYC EMKYKPNVLD 120
  121 EVINDTYGAP DLTKSYTDKE G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [142-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSDEIMLEDE SGRVLLVGDF IRSTPFITGV VVGILGMEAE AGTFQVLDIC YPTPLPQNPF  60
   61 PAPIATCPTR GKIALVSGLN LNNTSPDRLL RLEILREFLM GRINNKIDDI SLIGRLLICG 120
  121 NSVDFDIKSV NKDELMISLT EFSKFLHNIL PSISVDIMPG TNDPSDKSLP QQPFHKSLFD 180
  181 KSLESYFNGS NKEILNLVTN PYEFSYNGVD VLAVSGKNIN DICKYVIPSN DNGESENKVE 240
  241 EGESNDFKDD IEHRLDLMEC TMKWQNIAPT APDTLWCYPY TDKDPFVLDK WPHVYIVANQ 300
  301 PYFGTRVVEI GGKNIKIISV PEFSSTGMII LLDLETLEAE TVKIDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
hydrolase activity 2.89784024382425 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.54644459918406 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.75775204356118 bayes_pls_golite062009
transferase activity 1.71554219929081 bayes_pls_golite062009
binding 1.30309680165893 bayes_pls_golite062009
catalytic activity 1.30037658165549 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.17916462117542 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.950264524479969 bayes_pls_golite062009
phosphatase activity 0.829761417192212 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.768201004870964 bayes_pls_golite062009
structural molecule activity 0.211411396269789 bayes_pls_golite062009
protein binding 0.20380491058914 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle