YRC Public Data Repository - Protein Structure Prediction

Protein:	EXO70
Organism:	Saccharomyces cerevisiae
Length:	623 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EXO70.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[2..622]	[4..628]
E70B1_ARATH - Exocyst complex component EXO70B1 OS=Arabidopsis thaliana GN=EXO70B1 PE=1 SV=1	0.0	[6..623]	[4..617]
EXO70 - Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), whi... gi\|190409415 - gi\|190409415\|gb\|EDV12680.1\| exocyst complex component EXO70 [Saccharomyces cerevisiae RM11-1a] gi\|151945243 - gi\|151945243\|gb\|EDN63492.1\| exocyst complex component [Saccharomyces cerevisiae YJM789] EXO70_YEAST - Exocyst complex component EXO70 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EXO70 PE...	0.0	[1..623]	[1..623]
gi\|19386798 - gi\|19386798\|dbj\|BAB86177.1\| putative leucine zipper protein [Oryza sativa Japonica Group]	0.0	[10..622]	[14..639]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAEIDIDEA DVLVLSQELQ KTSKLTFEIN KSLKKIAATS NQSSQLFTPI LARNNVLTTL  60
   61 QRNIESTLNS VASVKDLANE ASKYEIILQK GINQVGLKQY TQVVHKLDDM LEDIQSGQAN 120
  121 REENSEFHGI LTHLEQLIKR SEAQLRVYFI SILNSIKPFD PQINITKKMP FPYYEDQQLG 180
  181 ALSWILDYFH GNSEGSIIQD ILVGERSKLI LKCMAF

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.48
Match:	1hciA
Description:	alpha-actinin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [217-533]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEPFAKEIST AKNAPYEKGS SGMNSYTEAL LGFIANEKSL VDDLYSQYTE SKPHVLSQIL  60
   61 SPLISAYAKL FGANLKIVRS NLENFGFFSF ELVESINDVK KSLRGKELQN YNLLQDCTQE 120
  121 VRQVTQSLFR DAIDRIIKKA NSISTIPSNN GVTEATVDTM SRLRKFSEYK NGCLGAMDNI 180
  181 TRENWLPSNY KEKEYTLQNE ALNWEDHNVL LSCFISDCID TLAVNLERKA QIALMPNQEP 240
  241 DVANPNSSKN KHKQRIGFFI LMNLTLVEQI VEKSELNLML AGEGHSRLER LKKRYISYMV 300
  301 SDWRDLTANL MDSVFID

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [534-623]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSGKKSKDKE QIKEKFRKFN EGFEDLVSKT KQYKLSDPSL KVTLKSEIIS LVMPMYERFY  60
   61 SRYKDSFKNP RKHIKYTPDE LTTVLNQLVR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits