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View Structure Prediction Details

Protein: EXO70
Organism: Saccharomyces cerevisiae
Length: 623 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EXO70.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..622] [4..628]
E70B1_ARATH - Exocyst complex component EXO70B1 OS=Arabidopsis thaliana GN=EXO70B1 PE=1 SV=1
0.0 [6..623] [4..617]
EXO70 - Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), whi...
gi|190409415 - gi|190409415|gb|EDV12680.1| exocyst complex component EXO70 [Saccharomyces cerevisiae RM11-1a]
gi|151945243 - gi|151945243|gb|EDN63492.1| exocyst complex component [Saccharomyces cerevisiae YJM789]
EXO70_YEAST - Exocyst complex component EXO70 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EXO70 PE...
0.0 [1..623] [1..623]
gi|19386798 - gi|19386798|dbj|BAB86177.1| putative leucine zipper protein [Oryza sativa Japonica Group]
0.0 [10..622] [14..639]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAEIDIDEA DVLVLSQELQ KTSKLTFEIN KSLKKIAATS NQSSQLFTPI LARNNVLTTL  60
   61 QRNIESTLNS VASVKDLANE ASKYEIILQK GINQVGLKQY TQVVHKLDDM LEDIQSGQAN 120
  121 REENSEFHGI LTHLEQLIKR SEAQLRVYFI SILNSIKPFD PQINITKKMP FPYYEDQQLG 180
  181 ALSWILDYFH GNSEGSIIQD ILVGERSKLI LKCMAF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.48
Match: 1hciA
Description: alpha-actinin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [217-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEPFAKEIST AKNAPYEKGS SGMNSYTEAL LGFIANEKSL VDDLYSQYTE SKPHVLSQIL  60
   61 SPLISAYAKL FGANLKIVRS NLENFGFFSF ELVESINDVK KSLRGKELQN YNLLQDCTQE 120
  121 VRQVTQSLFR DAIDRIIKKA NSISTIPSNN GVTEATVDTM SRLRKFSEYK NGCLGAMDNI 180
  181 TRENWLPSNY KEKEYTLQNE ALNWEDHNVL LSCFISDCID TLAVNLERKA QIALMPNQEP 240
  241 DVANPNSSKN KHKQRIGFFI LMNLTLVEQI VEKSELNLML AGEGHSRLER LKKRYISYMV 300
  301 SDWRDLTANL MDSVFID

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [534-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSGKKSKDKE QIKEKFRKFN EGFEDLVSKT KQYKLSDPSL KVTLKSEIIS LVMPMYERFY  60
   61 SRYKDSFKNP RKHIKYTPDE LTTVLNQLVR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.793 a.7.1 Spectrin repeat
View Download 0.684 f.15.1 Small-conductance potassium channel
View Download 0.673 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.748 a.112.1 Description not found.
View Download 0.685 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.647 a.7.1 Spectrin repeat
View Download 0.637 a.25.1 Ferritin-like
View Download 0.622 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.615 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.607 a.30.1 ROP protein
View Download 0.604 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.587 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.576 a.7.1 Spectrin repeat
View Download 0.571 f.14.1 Voltage-gated potassium channels
View Download 0.565 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.558 a.24.1 Apolipoprotein
View Download 0.549 a.7.1 Spectrin repeat
View Download 0.532 a.7.1 Spectrin repeat
View Download 0.521 a.24.17 Group V grass pollen allergen
View Download 0.515 a.7.5 Tubulin chaperone cofactor A
View Download 0.514 f.13.1 Family A G protein-coupled receptor-like
View Download 0.514 f.13.1 Family A G protein-coupled receptor-like
View Download 0.513 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.507 a.24.9 alpha-catenin/vinculin
View Download 0.501 a.7.1 Spectrin repeat
View Download 0.487 a.7.8 GAT domain
View Download 0.485 a.7.7 BAG domain
View Download 0.480 a.2.7 tRNA-binding arm
View Download 0.479 a.30.1 ROP protein
View Download 0.463 a.47.2 t-snare proteins
View Download 0.457 a.22.1 Histone-fold
View Download 0.451 a.19.1 Fertilization protein
View Download 0.448 d.197.1 Protein-L-isoaspartyl O-methyltransferase, C-terminal domain
View Download 0.445 a.22.1 Histone-fold
View Download 0.445 a.7.7 BAG domain
View Download 0.441 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.440 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.437 a.47.2 t-snare proteins
View Download 0.436 a.7.5 Tubulin chaperone cofactor A
View Download 0.434 a.47.2 t-snare proteins
View Download 0.428 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.422 a.25.1 Ferritin-like
View Download 0.415 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.414 a.2.7 tRNA-binding arm
View Download 0.414 a.47.2 t-snare proteins
View Download 0.411 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.409 a.24.17 Group V grass pollen allergen
View Download 0.406 f.13.1 Family A G protein-coupled receptor-like
View Download 0.405 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.402 a.2.7 tRNA-binding arm
View Download 0.397 a.63.1 Apolipophorin-III
View Download 0.395 f.15.1 Small-conductance potassium channel
View Download 0.393 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.390 a.47.2 t-snare proteins
View Download 0.390 a.47.2 t-snare proteins
View Download 0.386 f.15.1 Small-conductance potassium channel
View Download 0.384 a.24.17 Group V grass pollen allergen
View Download 0.382 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.377 f.15.1 Small-conductance potassium channel
View Download 0.376 a.126.1 Serum albumin-like
View Download 0.373 a.21.1 HMG-box
View Download 0.373 a.22.1 Histone-fold
View Download 0.372 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.367 a.47.2 t-snare proteins
View Download 0.367 a.4.5 "Winged helix" DNA-binding domain
View Download 0.365 a.22.1 Histone-fold
View Download 0.364 a.74.1 Cyclin-like
View Download 0.363 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.359 a.47.2 t-snare proteins
View Download 0.352 a.1.1 Globin-like
View Download 0.351 a.30.1 ROP protein
View Download 0.349 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.348 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.347 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.346 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.346 a.7.7 BAG domain
View Download 0.344 f.16.1 Gated mechanosensitive channel
View Download 0.341 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.340 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.340 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.338 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.336 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.335 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.332 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.328 a.47.2 t-snare proteins
View Download 0.327 a.112.1 Description not found.
View Download 0.324 a.7.8 GAT domain
View Download 0.322 a.4.1 Homeodomain-like
View Download 0.321 a.30.1 ROP protein
View Download 0.317 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.316 d.110.4 SNARE-like
View Download 0.311 a.112.1 Description not found.
View Download 0.310 a.47.2 t-snare proteins
View Download 0.307 a.112.1 Description not found.
View Download 0.303 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.300 a.7.8 GAT domain
View Download 0.297 a.123.1 Nuclear receptor ligand-binding domain
View Download 0.295 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.293 a.74.1 Cyclin-like
View Download 0.292 d.58.13 Anticodon-binding domain of PheRS
View Download 0.292 a.158.1 F-box domain
View Download 0.289 a.7.1 Spectrin repeat
View Download 0.289 a.7.1 Spectrin repeat
View Download 0.289 a.40.1 Calponin-homology domain, CH-domain
View Download 0.287 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.285 a.7.8 GAT domain
View Download 0.285 a.47.2 t-snare proteins
View Download 0.284 a.24.9 alpha-catenin/vinculin
View Download 0.283 i.1.1 Ribosome and ribosomal fragments
View Download 0.281 a.24.9 alpha-catenin/vinculin
View Download 0.281 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.280 a.144.1 PABC (PABP) domain
View Download 0.277 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.276 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.276 a.7.7 BAG domain
View Download 0.275 a.2.3 Chaperone J-domain
View Download 0.275 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.273 f.13.1 Family A G protein-coupled receptor-like
View Download 0.273 a.77.1 DEATH domain
View Download 0.269 d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.267 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.263 a.30.1 ROP protein
View Download 0.263 a.47.2 t-snare proteins
View Download 0.263 f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.262 d.197.1 Protein-L-isoaspartyl O-methyltransferase, C-terminal domain
View Download 0.262 d.58.48 MTH1187-like
View Download 0.262 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.261 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.257 a.19.1 Fertilization protein
View Download 0.256 f.13.1 Family A G protein-coupled receptor-like
View Download 0.255 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.254 a.74.1 Cyclin-like
View Download 0.254 a.16.1 S15/NS1 RNA-binding domain
View Download 0.253 d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.252 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.250 a.22.1 Histone-fold
View Download 0.250 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.249 a.4.5 "Winged helix" DNA-binding domain
View Download 0.247 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.247 a.24.9 alpha-catenin/vinculin
View Download 0.246 a.16.1 S15/NS1 RNA-binding domain
View Download 0.246 a.24.1 Apolipoprotein
View Download 0.246 a.24.9 alpha-catenin/vinculin
View Download 0.245 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.245 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.243 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.242 a.4.1 Homeodomain-like
View Download 0.242 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.241 a.22.1 Histone-fold
View Download 0.241 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.239 f.14.1 Voltage-gated potassium channels
View Download 0.236 a.4.5 "Winged helix" DNA-binding domain
View Download 0.236 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.236 a.7.7 BAG domain
View Download 0.235 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.234 a.21.1 HMG-box
View Download 0.233 a.2.7 tRNA-binding arm
View Download 0.233 a.74.1 Cyclin-like
View Download 0.231 a.77.1 DEATH domain
View Download 0.231 a.3.1 Cytochrome c
View Download 0.230 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.230 a.19.1 Fertilization protein
View Download 0.229 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.228 a.2.7 tRNA-binding arm
View Download 0.228 a.47.2 t-snare proteins
View Download 0.225 f.14.1 Voltage-gated potassium channels
View Download 0.225 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.225 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.225 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.224 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.223 a.142.1 PTS-regulatory domain, PRD
View Download 0.222 d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.222 a.7.5 Tubulin chaperone cofactor A
View Download 0.222 a.4.5 "Winged helix" DNA-binding domain
View Download 0.220 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.220 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.220 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.219 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.219 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.218 a.22.1 Histone-fold
View Download 0.217 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.217 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.216 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.215 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.215 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.214 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.214 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.213 a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.213 a.4.5 "Winged helix" DNA-binding domain
View Download 0.212 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.211 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.210 d.57.1 DNA damage-inducible protein DinI
View Download 0.210 a.24.9 alpha-catenin/vinculin
View Download 0.209 a.24.3 Cytochromes
View Download 0.209 a.22.1 Histone-fold
View Download 0.209 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.206 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.205 a.77.1 DEATH domain
View Download 0.205 a.7.8 GAT domain
View Download 0.204 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.204 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.203 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.203 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.201 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.201 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.200 f.16.1 Gated mechanosensitive channel


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle