| Protein: | JEM1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 645 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JEM1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..645] | [48..692] |
|
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2.0E-95 | [184..643] | [71..503] |
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6.0E-95 | [184..643] | [71..503] |
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8.0E-95 | [184..643] | [71..503] |
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2.0E-93 | [184..643] | [71..503] |
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2.0E-82 | [181..643] | [73..501] |
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2.0E-76 | [88..604] | [503..1058] |
|
Region A: Residues: [1-111] |
1 11 21 31 41 51
| | | | | |
1 MILISGYCLL VYSVILPVLI SASKLCDLAE LQRLNKNLKV DTESLPKYQW IAGQLEQNCM 60
61 TADPASENMS DVIQLANQIY YKIGLIQLSN DQHLRAINTF EKIVFNETYK G
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.682 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.681 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.509 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.505 | c.44.1 | Phosphotyrosine protein phosphatases I |
| View | Download | 0.456 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.434 | a.24.4 | Hemerythrin |
| View | Download | 0.392 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.390 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.390 | a.7.1 | Spectrin repeat |
| View | Download | 0.358 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.345 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.336 | a.7.7 | BAG domain |
| View | Download | 0.322 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.317 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.316 | a.4.1 | Homeodomain-like |
| View | Download | 0.302 | a.1.1 | Globin-like |
| View | Download | 0.299 | a.1.1 | Globin-like |
| View | Download | 0.297 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.273 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.271 | a.1.1 | Globin-like |
| View | Download | 0.267 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.264 | a.83.1 | Guanido kinase N-terminal domain |
| View | Download | 0.263 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.260 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.260 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.254 | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.249 | a.25.1 | Ferritin-like |
| View | Download | 0.247 | a.4.1 | Homeodomain-like |
| View | Download | 0.242 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.242 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.228 | a.2.7 | tRNA-binding arm |
| View | Download | 0.227 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.226 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.223 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.220 | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.214 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.212 | a.4.1 | Homeodomain-like |
| View | Download | 0.210 | a.46.1 | Methionine synthase domain |
| View | Download | 0.205 | d.224.1 | SufE-like |
| View | Download | 0.205 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.201 | a.1.1 | Globin-like |
| View | Download | 0.201 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.201 | a.4.11 | RNA polymerase subunit RPB10 |
| Term | Confidence | Notes |
| binding | 2.14253214573541 | bayes_pls_golite062009 |
| protein binding | 1.83529176977066 | bayes_pls_golite062009 |
| heat shock protein binding | 1.35268080101836 | bayes_pls_golite062009 |
| unfolded protein binding | 1.03065657981002 | bayes_pls_golite062009 |
| soluble NSF attachment protein activity | 0.87758140474425 | bayes_pls_golite062009 |
| hydrolase activity | 0.446391173448268 | bayes_pls_golite062009 |
| nucleic acid binding | 0.42893085337736 | bayes_pls_golite062009 |
| transcription regulator activity | 0.422422877754753 | bayes_pls_golite062009 |
| DNA binding | 0.2126480534609 | bayes_pls_golite062009 |
|
Region A: Residues: [112-310] |
1 11 21 31 41 51
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1 SFGKLAEKRL QELYVDFGMW DKVHQKDDQY AKYLSLNETI RNKISSKDVS VEEDISELLR 60
61 ITPYDVNVLS THIDVLFHKL AEEIDVSLAA AIILDYETIL DKHLASLSID TRLSIHYVIS 120
121 VLQTFVLNSD ASFNIRKCLS IDMDYDKCKK LSLTISKLNK VNPSKRQILD PATYAFENKK 180
181 FRSWDRIIEF YLKDKKPFI
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| Detection Method: | |
| Confidence: | 6.69897 |
| Match: | 1a17__ |
| Description: | Protein phosphatase 5 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| unfolded protein binding | 3.04403163860617 | bayes_pls_golite062009 |
| heat shock protein binding | 2.17994194200939 | bayes_pls_golite062009 |
| binding | 2.0541759325193 | bayes_pls_golite062009 |
| protein binding | 1.81676109739118 | bayes_pls_golite062009 |
| chaperone binding | 1.61155546076854 | bayes_pls_golite062009 |
| Hsp70 protein binding | 0.541755903922701 | bayes_pls_golite062009 |
| nucleic acid binding | 0.435350029200482 | bayes_pls_golite062009 |
| transcription regulator activity | 0.374102625114103 | bayes_pls_golite062009 |
| DNA binding | 0.1383523679652 | bayes_pls_golite062009 |
| catalytic activity | 0.106988907594358 | bayes_pls_golite062009 |
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Region A: Residues: [311-369] |
1 11 21 31 41 51
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1 TPMKILNKDT NFKNNYFFLE EIIKQLIEDV QLSRPLAKNL FEDPPITDGF VKPKSYYHT
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.591 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.732 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.596 | a.64.1 | Saposin |
| View | Download | 0.458 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.423 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.388 | a.4.1 | Homeodomain-like |
| View | Download | 0.374 | a.164.1 | C-terminal domain of DFF45/ICAD (DFF-C domain) |
| View | Download | 0.372 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.364 | a.4.1 | Homeodomain-like |
| View | Download | 0.363 | a.5.2 | UBA-like |
| View | Download | 0.326 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.322 | a.28.1 | ACP-like |
| View | Download | 0.290 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.281 | a.140.2 | SAP domain |
| View | Download | 0.280 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.277 | a.39.1 | EF-hand |
| View | Download | 0.273 | d.45.1 | ClpS-like |
| View | Download | 0.267 | a.4.2 | Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
| View | Download | 0.254 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.251 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.246 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.238 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.234 | a.5.2 | UBA-like |
| View | Download | 0.230 | a.126.1 | Serum albumin-like |
| View | Download | 0.223 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.223 | a.74.1 | Cyclin-like |
| View | Download | 0.211 | a.4.7 | Ribosomal protein L11, C-terminal domain |
| View | Download | 0.201 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
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Region A: Residues: [370-531] |
1 11 21 31 41 51
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1 DYLVYIDSIL CQASSMSPDV KRAKLAAPFC KKSLRHSLTL ETWKHYQDAK SEQKPLPETV 60
61 LSDVWNSNPH LLMYMVNSIL NKSRSKPHSQ FKKQLYDQIN KFFQDNGLSE STNPYVMKNF 120
121 RLLQKQLQTY KEHKHRNFNQ QYFQQQQQQQ QHQRHQAPPA AP
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [532-645] |
1 11 21 31 41 51
| | | | | |
1 NYDPKKDYYK ILGVSPSASS KEIRKAYLNL TKKYHPDKIK ANHNDKQESI HETMSQINEA 60
61 YETLSDDDKR KEYDLSRSNP RRNTFPQGPR QNNMFKNPGS GFPFGNGFKM NFGL
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| Detection Method: | |
| Confidence: | 141.28043 |
| Match: | 1xbl__ |
| Description: | DnaJ chaperone, N-terminal (J) domain |
Matching Structure (courtesy of the PDB): |
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