YRC Public Data Repository - Protein Structure Prediction

Protein:	YIR007W
Organism:	Saccharomyces cerevisiae
Length:	764 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIR007W.

Description	E-value	Query Range	Subject Range
YIS7_YEAST - Uncharacterized glycosyl hydrolase YIR007W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ... YIR007W - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...	0.0	[1..764]	[1..764]
gi\|10716082 - gi\|10716082\|dbj\|BAB16370.1\| endoglycoceramidase [Cyanea nozakii]	8.0E-87	[12..285]	[40..262]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-64	[8..269]	[39..228]
gi\|2337906 - gi\|2337906\|gb\|AAB67050.1\| endoglycoceramidase II [Rhodococcus sp.]	1.0E-57	[12..269]	[45..237]
gi\|15023717, gi\|... - gi\|15894113\|ref\|NP_347462.1\| endoglucanase family protein 5 [Clostridium acetobutylicum ATCC 824], g... gi\|25315443 - pir\|\|G97001 endoglucanase family 5 [imported] - Clostridium acetobutylicum	6.0E-4	[74..133]	[77..135]
GUNE_CLOTM - Endoglucanase E OS=Clostridium thermocellum GN=celE PE=1 SV=1	0.001	[2..133]	[28..150]

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Predicted Domain #1

Region A:
Residues: [1-69]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAKIHISAD GQFCDKDGNE IQLRGVNLDP SVKIPAKPFL STHAPIENDT FFEDADKVSF  60
   61 INHPLVLDD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [70-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEQHIIRLKS LGYNTIRLPF TWESLEHAGP GQYDFDYMDY IVEVLTRINS VQQGMYIYLD  60
   61 PHQDVWSRFS GGSGAPLWTL YCAGFQPANF LATDAAIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.30103
Match:	1edg__
Description:	Endoglucanase CelA
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [168-764]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNYYIDPKTG REVGKDEESY PKMVWPTNYF KLACQTMFTL FFGGKQYAPK CTINGENIQD  60
   61 YLQGRFNDAI MTLCARIKEK APELFESNCI IGLESMNEPN CGYIGETNLD VIPKERNLKL 120
  121 GKTPTAFQSF MLGEGIECTI DQYKRTFFGF SKGKPCTINP KGKKAWLSAE ERDAIDAKYN 180
  181 WERNPEWKPD TCIWKLHGVW EIQNGKRPVL LKPNYFSQPD ATVFINNHFV DYYTGIYNKF 240
  241 REFDQELFII IQPPVMKPPP NLQNSKILDN RTICACHFYD GMTLMYKTWN KRIGIDTYGL 300
  301 VNKKYSNPAF AVVLGENNIR KCIRKQLSEM QKDAKSMLGK KVPVFFTEIG IPFDMDDKKA 360
  361 YITNDYSSQT AALDALGFAL EGSNLSYTLW CYCSINSHIW GDNWNNEDFS IWSPDDKPLY 420
  421 HDTRAKTPTP EPSPASTVAS VSTSTSKSGS SQPPSFIKPD NHLDLDSPSC TLKSDLSGFR 480
  481 ALDAIMRPFP IQIHGRFEFA EFNLCNKSYL LKLVGKTTPE QITVPTYIFI PRHHFTPSRL 540
  541 SIRSSSGHYT YNTDYQVLEW FHEPGHQFIE ICAKSKSRPN TPGSDTSNDL PAECVIS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits