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View Structure Prediction Details

Protein: DPH1
Organism: Saccharomyces cerevisiae
Length: 425 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DPH1.

Description E-value Query
Range
Subject
Range
DPH1_YEAST - Diphthamide biosynthesis protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DPH1 ...
DPH1 - Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is...
0.0 [1..425] [1..425]
SPBC3B8.05 - diphthamide biosynthesis protein
DPH1_SCHPO - Diphthamide biosynthesis protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dph1 PE...
0.0 [8..415] [6..413]
gi|1438796 - gi|1438796|gb|AAB36421.1| OVCA1=candidate tumor suppressor [human, fetal brain, Peptide, 443 aa]
0.0 [43..415] [25..392]
dph-1 - diptheria toxin resistance protein status:Partially_confirmed UniProt:P49958 protein_id:CAA85493.1
0.0 [46..415] [2..369]
gi|220943026, gi... - gi|220953130|gb|ACL89108.1| CG11652-PA [synthetic construct], gi|220943026|gb|ACL84056.1| CG11652-PA...
CG11652-PB, CG11... - This gene is referred to in FlyBase by the symbol Dmel\CG11652 (CG11652, FBgn0036194). It is a prote...
0.0 [39..415] [29..403]
gi|10176920 - gi|10176920|dbj|BAB10164.1| unnamed protein product [Arabidopsis thaliana]
0.0 [39..402] [26..391]
DPH1_ENCCU - Diphthamide biosynthesis protein 1 OS=Encephalitozoon cuniculi (strain GB-M1) GN=DPH1 PE=3 SV=1
DPH1_ENCCU - Diphthamide biosynthesis protein 1 OS=Encephalitozoon cuniculi GN=DPH1 PE=3 SV=1
0.0 [59..416] [70..409]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSTESKKQ PRRRFIGRKS GNSNNDKLTT VAENGNEIIH KQKSRIALGR SVNHVPEDIL  60
   61 NDKELNEAIK LLPSNYNFEI HKTVWNIRKY NAKRIALQMP EGLLIYSLII SDILEQFCGV 120
  121 ETLVMGDVSY GACCIDDFTA RALDCDFIVH YAHSCLVPID VT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [163-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIKVLYVFVT INIQEDHIIK TLQKNFPKGS RIATFGTIQF NPAVHSVRDK LLNDEEHMLY  60
   61 IIPP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [282-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKFTREGYDQ KQLVEVRAEA IEVARKGKVF GLILGALGRQ GNLNTVKNLE KNLIAAGKTV  60
   61 VKIILSEVFP QKLAMFDQID VFVQVACPRL SIDWGYAFNK PLLTPYEASV LLKKDVMFSE 120
  121 KYYPMDYYEA KGYGRGETPK HAIE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.04
Match: 1jzxK
Description: 50S subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [227-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIKPLSRGEV LGCTSERLDK EQYDAMVFIG DGRFHLESAM IHNPEIPAFK YDPYN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.04
Match: 1jzxK
Description: 50S subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle