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View Structure Prediction Details

Protein: SGA1
Organism: Saccharomyces cerevisiae
Length: 549 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SGA1.

Description E-value Query
Range
Subject
Range
SGA1 - Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during sta...
AMYG_YEAST - Glucoamylase, intracellular sporulation-specific OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
0.0 [1..549] [1..549]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [26..509] [294..777]
gi|113798 - gi|113798|sp|P04065.2|AMYH_YEAST RecName: Full=Glucoamylase S1; AltName: Full=Glucan 1,4-alpha-gluco...
AMYH_SACDI - (P04065) Glucoamylase S1 precursor (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase) (1,4-alpha-D-glucan g...
0.0 [26..509] [283..766]
AMYG_ASPSH - Glucoamylase OS=Aspergillus shirousami GN=glaA PE=3 SV=1
gi|83686 - gi|83686|pir||JQ0607 glucan 1,4-alpha-glucosidase (EC 3.2.1.3) precursor - Aspergillus sp
0.0 [56..546] [1..456]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [56..546] [1..457]
AMYG_ASPKA - Glucoamylase I OS=Aspergillus kawachii GN=gaI PE=1 SV=1
gi|83647 - pir||JT0479 glucan 1,4-alpha-glucosidase (EC 3.2.1.3) precursor - Aspergillus awamori
0.0 [56..546] [1..456]

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Predicted Domain #1
Region A:
Residues: [1-71]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARQKMFYNK LLGMLSVGFG FAWALENITI YEFDFGKGIL DQSYGGVFSN NGPSQVQLRD  60
   61 AVLMNGTVVY D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
glucan 1,4-alpha-glucosidase activity 5.15001795572345 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.93931890201451 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 4.50236427574756 bayes_pls_golite062009
hydrolase activity 3.40551547894122 bayes_pls_golite062009
catalytic activity 1.16285856935495 bayes_pls_golite062009
trehalase activity 1.11894002588912 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.903455956749701 bayes_pls_golite062009
binding 0.668943347886111 bayes_pls_golite062009
protein binding 0.31260719357226 bayes_pls_golite062009
alpha,alpha-trehalase activity 0.17719034423607 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.0683547784833305 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [72-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGAWDSSAL EEWLQGQKKV 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [313-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDPANGFING KYNYIVGTPM IADTLRSGLD ISTLLAANTV HDAPSASHLP FDINDPAVLN  60
   61 TLHHLMLHMR SIYPINDSSK NATGIALGRY PEDVYDGYGF GEGNPWVLAT CTASTTLYQL 120
  121 IYRHISEQHD LVVPMNNDCS NAFWSELVFS NLTTLGNDEG YLILEFNTPA FNQTIQKIFQ 180
  181 LADSFLVKLK AHVGTDGELS EQFNKYTGFM QGAQHLTWSY TSFWDAYQIR QEVLQSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 877.9897
Match: 1ayx__
Description: Glucoamylase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [92-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIEKIFENIG PSAVYPSISP GVVIASPSQT HPDYFYQWIR DSALTINSIV SHSAGPAIET  60
   61 LLQYLNVSFH LQRSNNTLGA GIGYTNDTVA LGDPKWNVDN TAFTEDWGRP QNDGPALRSI 120
  121 AILKIIDYIK QSGTDLGAKY PFQSTADIFD DIVRWDLRFI IDHWNSSGFD LWEEVNGMHF 180
  181 FTLLVQLSAV DKSLSYFNAS ERSSPFVEEL RQTRRDISKF L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 877.9897
Match: 1ayx__
Description: Glucoamylase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle