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View Structure Prediction Details

Protein: SFB3
Organism: Saccharomyces cerevisiae
Length: 929 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SFB3.

Description E-value Query
Range
Subject
Range
SFB3 - Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat, required for cargo selection du...
SFB3_YEAST - SED5-binding protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SFB3 PE=1 SV=1
0.0 [1..929] [1..929]
gi|168267554 - gi|168267554|dbj|BAG09833.1| protein transport protein Sec24D [synthetic construct]
SEC24D - SEC24 family, member D (S. cerevisiae)
0.0 [3..905] [160..1031]
S24C_ARATH, SC24... - Protein transport protein Sec24-like CEF OS=Arabidopsis thaliana GN=CEF PE=1 SV=2, (Q9M291) Protein ...
0.0 [10..905] [224..1096]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [10..905] [223..1121]
gi|13365827 - gi|13365827|dbj|BAB39299.1| hypothetical protein [Macaca fascicularis]
0.0 [160..899] [9..760]

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Predicted Domain #1
Region A:
Residues: [1-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQQNILAAS VSALSLDEST VHTGGASSKK SRRPHRAYHN FSSGTVPTLG NSPYTTPQLN  60
   61 QQDGFQQPQA FTPKQFGGFN NGSGSVMSTP VMVSQERFGA SEASSPYGQS MLDMTAPQPT 120
  121 SHIVPTQRFE DQAQYLQRSF ETCRDSVPPL PTTQFYCVDQ GSCDPHLMSL SMYNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.9315281375853 bayes_pls_golite062009
binding 1.90456497151578 bayes_pls_golite062009
transporter activity 1.30184925420876 bayes_pls_golite062009
collagen binding 0.568860931913098 bayes_pls_golite062009
integrin binding 0.56855067092085 bayes_pls_golite062009
nucleic acid binding 0.464562340940318 bayes_pls_golite062009
protein complex binding 0.35582708645524 bayes_pls_golite062009
DNA binding 0.155617838235236 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0661625326929309 bayes_pls_golite062009
pyrophosphatase activity 0.027305897174472 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0179622467180781 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0153681945260867 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [176-332]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PESEHLRAAT KLPLGLTIQP FSTLTPNDAE VPTIPLPMDG TPLRCRRCRA YANPKFQFTY  60
   61 DSSVICNICR VKMQVPGEHF APMGPNGQRS DLNEKSELLH GTVDFLVPSI YNAIQEKELL 120
  121 PLHYVFLIDV SLLANENGSS LAMVEGVRSC IEYISDF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [333-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPNCEVAIIV YDNKLRFFNL RPDLDNAQEY IVSELDDVFL PFYNGLFVKP GNSMKIINDT  60
   61 LIKISGYIST DKYSHVPQVC YGSALQAAKL ALDTVTGGQG GKIICSLNSL PTIGNGNLSL 120
  121 KRDNAHIAHV KCDNGFYKKL ASDFLKSYIS LDLYVTNAGF IDMATVGHPV EMTSGILKYY 180
  181 PHFQQETDAF TLVNDMVTNV SNIVGYQALL KVRCSTGLSV EQYYCDSSDN TDHDPIIPVL 240
  241 TRDTTLDVLL KYDSKIKTGT DVHFQTALLY TDIDGVRKVR SINTSGAVSN NIREIFKFIN 300
  301 QNPVMRIMIK DVIKTLGD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [651-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDFVKIRRLI DDKMVEILTQ YRGLVSSNSS TQLILPDSIK TLPAYMLAFE KSELMKP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.719 a.144.1 PABC (PABP) domain
View Download 0.698 a.30.1 ROP protein
View Download 0.603 a.2.7 tRNA-binding arm
View Download 0.490 a.60.12 DNA polymerase beta-like, second domain
View Download 0.473 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.453 a.16.1 S15/NS1 RNA-binding domain
View Download 0.425 a.16.1 S15/NS1 RNA-binding domain
View Download 0.414 a.4.1 Homeodomain-like
View Download 0.379 a.74.1 Cyclin-like
View Download 0.373 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.363 f.15.1 Small-conductance potassium channel
View Download 0.342 a.161.1 beta-catenin-interacting protein ICAT
View Download 0.322 a.112.1 Description not found.
View Download 0.321 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.315 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.313 a.4.5 "Winged helix" DNA-binding domain
View Download 0.285 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.277 a.112.1 Description not found.
View Download 0.273 a.140.1 LEM domain
View Download 0.260 a.50.1 Anaphylotoxins (complement system)
View Download 0.258 a.4.5 "Winged helix" DNA-binding domain
View Download 0.256 a.4.1 Homeodomain-like
View Download 0.253 a.4.5 "Winged helix" DNA-binding domain
View Download 0.252 d.58.24 CheY-binding domain of CheA
View Download 0.250 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.249 g.53.1 TAZ domain
View Download 0.246 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.230 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.227 a.6.1 Putative DNA-binding domain
View Download 0.225 d.59.1 Ribosomal protein L30p/L7e
View Download 0.222 a.60.2 RuvA domain 2-like
View Download 0.219 d.58.49 YajQ-like
View Download 0.215 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.209 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.208 d.201.1 SRP19
View Download 0.207 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.206 a.6.1 Putative DNA-binding domain
View Download 0.203 a.46.1 Methionine synthase domain
View Download 0.202 a.30.2 Homodimeric domain of signal transducing histidine kinase

Predicted Domain #5
Region A:
Residues: [708-929]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAQSTRGNER IYDLLKYDSL NSAQLCYKLY PQIVPFHVLL EETDLTFYDA NDKLLQINSS  60
   61 SINNLSVRAS HSNFINGGCY LIFQGDTIYL WFNENTNRML LQDLLSVDES LPVSQISLFS 120
  121 GTLPETGTSI NQKASNVIKN WQQVVNKSSL PLVLLRPNVD QYYSNVMSQL LCEDKTVNRI 180
  181 ESYDNYLVIM HKKIQEKLQK DDFIKVSTAA THENIHQKFV QF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle