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View Structure Prediction Details

Protein: RPF1
Organism: Saccharomyces cerevisiae
Length: 295 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPF1.

Description E-value Query
Range
Subject
Range
gi|151944036 - gi|151944036|gb|EDN62329.1| conserved protein [Saccharomyces cerevisiae YJM789]
gi|207344657 - gi|207344657|gb|EDZ71727.1| YHR088Wp-like protein [Saccharomyces cerevisiae AWRI1631]
RPF1_YEAST - Ribosome production factor 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPF1 PE=1 S...
RPF1 - Nucleolar protein involved in the assembly and export of the large ribosomal subunit; constituent of...
gi|190405870 - gi|190405870|gb|EDV09137.1| ribosome production factor 1 [Saccharomyces cerevisiae RM11-1a]
3.0E-81 [1..295] [1..295]
gi|5834783 - gi|5834783|emb|CAB55338.1| hypothetical protein [Yarrowia lipolytica]
5.0E-81 [6..295] [47..333]
gi|12850634, gi|... - gi|30519917|ref|NP_848716.1| U3 snoRNP protein 4 homolog [Mus musculus], gi|12850634|dbj|BAB28797.1|...
3.0E-77 [7..295] [2..288]
RPF1 - ribosome production factor 1 homolog (S. cerevisiae)
gi|114557449 - gi|114557449|ref|XP_524755.2| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
2.0E-76 [9..295] [57..349]
gi|7268199, gi|5... - gi|7268199|emb|CAB77726.1| hypothetical protein [Arabidopsis thaliana], gi|58652114|gb|AAW80882.1| A...
7.0E-73 [9..295] [39..343]
gi|16768354 - gi|16768354|gb|AAL28396.1| GM02712p [Drosophila melanogaster]
2.0E-71 [7..292] [2..282]
CE18464 - status:Confirmed UniProt:O62518 protein_id:CAB05841.1
4.0E-71 [7..295] [2..283]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALGNEINIT NKLKRQEIFA DIKHEKNKER HTMRRKRAKE ERENPELREQ RLKENVTQTI  60
   61 ENTRVYDETI NKEVEGDEDD LMRYFNSNSN EPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIFLTTNVNA KKSAYEFANI LIEILPNVTF VKRKFGYKLK EISDICIKRN FTDIVIINED  60
   61 KKKVTGLTFI HLPEGPTFYF KLSSFVEVKK IVGHGRPTSH IPELILNNFQ TRLGQTVGRL 120
  121 FQSILPQNPD IEGRQVITLH NQRDYIFFRR HRYVFKDNER VGLQELGPQF TLKLKRLQRG 180
  181 IKEETEWEHK PEMDKEKKKF YL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 35.275724
Match: PF01945
Description: No description for PF01945 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
aminoacyl-tRNA ligase activity 3.58650371779212 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 3.58624422951947 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.58624422951947 bayes_pls_golite062009
ligase activity 2.44518871945794 bayes_pls_golite062009
proline-tRNA ligase activity 2.35871952544841 bayes_pls_golite062009
binding 1.78917266819015 bayes_pls_golite062009
catalytic activity 0.902495165806215 bayes_pls_golite062009
protein binding 0.665778090365515 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [185-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGHGRPTSHI PELILNNFQT RLGQTVGRLF QSILPQNPDI EGRQVITLHN QRDYIFFRRH  60
   61 RYVFKDNERV GLQELGPQFT LKLKRLQRGI KEETEWEHKP EMDKEKKKFY L

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.61
Match: 2cxhA
Description: Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle