YRC Public Data Repository - Protein Structure Prediction

Protein:	SMF2
Organism:	Saccharomyces cerevisiae
Length:	549 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMF2.

Description	E-value	Query Range	Subject Range
gi\|207344708 - gi\|207344708\|gb\|EDZ71762.1\| YHR050Wp-like protein [Saccharomyces cerevisiae AWRI1631] SMF2 - Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valen... gi\|151943995 - gi\|151943995\|gb\|EDN62288.1\| suppressor of mitochondria import function [Saccharomyces cerevisiae YJM... SMF2_YEAST - Manganese transporter SMF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SMF2 PE=3 SV=...	0.0	[1..549]	[1..549]
gi\|4433391 - gi\|4433391\|gb\|AAD20722.1\| natural resistance associated macrophage protein-beta [Oncorhynchus mykiss...	0.0	[5..463]	[11..466]
NRAM2_MOUSE - Natural resistance-associated macrophage protein 2 OS=Mus musculus GN=Slc11a2 PE=1 SV=2	0.0	[2..463]	[15..472]
gi\|149032038, gi... - gi\|6981288\|ref\|NP_037305.1\| solute carrier family 11 (proton-coupled divalent metal ion transporters...	0.0	[2..463]	[15..472]
gi\|57164361, gi\|... - gi\|57164361\|ref\|NP_001009345.1\| natural resistance associated macrophage protein [Ovis aries], gi\|40...	0.0	[1..463]	[24..481]

Back

Predicted Domain #1

Region A:
Residues: [1-75]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSQEYEPIQ WSDESQTNND SVNDAYADVN TTHESRRRTT LQPNSTSQSM IGTLRKYARF  60
   61 IGPGLMVSVS YMDPG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [76-495]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYSTAVAAGS AHRYKLLFSV LVSNFMAAFW QYLCARLGAV TGLDLAQNCK KHLPFGLNIT  60
   61 LYILAEMAII ATDLAEVVGT AISLNILFHI PLALGVILTV VDVLIVLLAY KPNGSMKGIR 120
  121 IFEAFVSLLV VLTVVCFTVE LFYAKLGPAK EIFSGFLPSK AVFEGDGLYL SLAILGATVM 180
  181 PHSLYLGSGV VQPRLREYDI KNGHYLPDAN DMDNNHDNYR PSYEAISETL HFTITELLIS 240
  241 LFTVALFVNC AILIVSGATL YGSTQNAEEA DLFSIYNLLC STLSKGAGTV FVLALLFSGQ 300
  301 SAGIVCTLSG QMVSEGFLNW TVSPALRRSA TRAVAITPCL ILVLVAGRSG LSGALNASQV 360
  361 VLSLLLPFVS APLLYFTSSK KIMRVQLNRT KELSRTTDKK PVADRTEDDE TIELEEMGIG 420
  421

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	242.886057
Match:	PF01566
Description:	Natural resistance-associated macrophage protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [496-549]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSQERSLVS PAPEYKDMSN GMIVTVLAII VWLIISGLNF YMLLGFTTGK EVHL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits