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View Structure Prediction Details

Protein: YHR022C
Organism: Saccharomyces cerevisiae
Length: 256 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHR022C.

Description E-value Query
Range
Subject
Range
ARA5_ARATH - Ras-related protein ARA-5 - Arabidopsis thaliana (Mouse-ear cress)
2.0E-72 [3..252] [45..231]
gi|1370166 - gi|1370166|emb|CAA98160.1| RAB1C [Lotus japonicus]
2.0E-71 [14..252] [1..176]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-71 [14..252] [1..176]
gi|4586580 - gi|4586580|dbj|BAA76422.1| rab-type small GTP-binding protein [Cicer arietinum]
2.0E-71 [14..252] [1..176]
RIC1_ORYSA - (P40392) Ras-related protein RIC1
4.0E-71 [14..252] [1..176]
gi|1616614 - gi|1616614|emb|CAA69701.1| small GTP-binding protein [Nicotiana plumbaginifolia]
1.0E-70 [14..252] [1..176]
RB11A_PONAB - Ras-related protein Rab-11A OS=Pongo abelii GN=RAB11A PE=2 SV=3
CCDS10212.1_1 - null
ENSCJAT00000014411 - null
RB11A_RABIT - Ras-related protein Rab-11A OS=Oryctolagus cuniculus GN=RAB11A PE=2 SV=3
RB11A_RAT - Ras-related protein Rab-11A OS=Rattus norvegicus GN=Rab11a PE=1 SV=3
RB11A_PONPY - Ras-related protein Rab-11A - Pongo pygmaeus (Orangutan)
RB11A_MOUSE - Ras-related protein Rab-11A OS=Mus musculus GN=Rab11a PE=1 SV=3
RB11A_CANLF - Ras-related protein Rab-11A OS=Canis lupus familiaris GN=RAB11A PE=2 SV=3
ENSMMUG000000080... - null, null
gi|123999492, gi... - gi|61355514|gb|AAX41148.1| RAB11A member RAS oncogene family [synthetic construct], gi|61355506|gb|A...
gi|114657631 - gi|114657631|ref|XP_510490.2| PREDICTED: similar to rab11 [Pan troglodytes]
tr|G3I0B0|G3I0B0... - Ras-related protein Rab-11A OS=Cricetulus griseus GN=I79_016788 PE=3 SV=1
tr|M3WVD0|M3WVD0... - RAB11A, member RAS oncogene family OS=Felis catus GN=RAB11A PE=4 SV=1
gi|76675213|ref|... - PREDICTED: similar to RAB11a, member RAS oncogene family isoform 2 [Bos taurus], Isoform of Q2TA29, ...
RB11A_PIG - Ras-related protein Rab-11A OS=Sus scrofa GN=RAB11A PE=2 SV=3
gi|126277069 - gi|126277069|ref|XP_001367185.1| PREDICTED: similar to rab11 [Monodelphis domestica]
RAB11A - RAB11A, member RAS oncogene family
2.0E-70 [15..254] [5..181]
RB11B_MOUSE - Ras-related protein Rab-11B OS=Mus musculus GN=Rab11b PE=1 SV=3
2.0E-70 [15..255] [5..182]
ENSPTRT00000019157 - null
tr|G3I5Q9|G3I5Q9... - Ras-related protein Rab-11B OS=Cricetulus griseus GN=I79_018814 PE=3 SV=1
RB11B_RAT - Ras-related protein Rab-11B OS=Rattus norvegicus GN=Rab11b PE=1 SV=4
gi|90085246 - gi|90085246|dbj|BAE91364.1| unnamed protein product [Macaca fascicularis]
gi|226529709, gi... - gi|226529709|ref|NP_001142168.1| hypothetical protein LOC100274335 [Zea mays], gi|194707448|gb|ACF87...
gi|61355645 - gi|61355645|gb|AAX41161.1| RAB11B member RAS oncogene family [synthetic construct]
RB11B_BOVIN - Ras-related protein Rab-11B OS=Bos taurus GN=RAB11B PE=2 SV=3
CCDS12201.1_1 - null
gi|109123235 - gi|109123235|ref|XP_001093925.1| PREDICTED: RAB11B, member RAS oncogene family [Macaca mulatta]
RAB11B - RAB11B, member RAS oncogene family
2.0E-70 [15..255] [5..182]

Back

Predicted Domain #1
Region A:
Residues: [1-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRLSYGAS LASIPRCFDL KSSKITVMGD DHSGKTSLVR SWLGSSFQIS DANRYRVSDL  60
   61 YHKTIQFDTL VKYYRTFGVK GQLPNYAGFK AKNSGTIYES CGNFLEERLI NANKSTAQRR 120
  121 TSIDVQVFDT NQMEVSYLSE LTTLQIRQSD AIILCFDSTN DSSLASLESY ICIIHHVRLE 180
  181 CELDIPIIIA CTKCDLDSER TITHEKVLTF IQELGFSPGN LDYFETSSKF NVNVEDLFLA 240
  241 VLLKIEKSKS DRRKLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.927757
Match: 3rabA_
Description: Rab3a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.36550713198424 bayes_pls_golite062009
catalytic activity 0.234613562021476 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.166100211611062 bayes_pls_golite062009
pyrophosphatase activity 0.159702441149605 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.149170905385965 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.147838751017739 bayes_pls_golite062009
hydrolase activity 0.0436758932827116 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle