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View Structure Prediction Details

Protein: PTI1
Organism: Saccharomyces cerevisiae
Length: 425 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTI1.

Description E-value Query
Range
Subject
Range
gi|416162 - gi|416162|dbj|BAA03953.1| hypothetical protein [Saccharomyces cerevisiae]
0.0 [1..425] [1..425]
gi|4574746 - gi|4574746|gb|AAD24197.1|AF136223_1 M3.4 protein [Brassica napus]
0.008 [264..345] [140..218]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDPRRRTGR HFLTPENLSS TLQITNLPPE WNQDIITSVV AGSGPVIDIK AKNDPRTGKL  60
   61 TGVLFDYLTS KDCKRAWEIL NRIENFPVKI EQIIPPNYKD HLR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.6
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [104-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETANKNSQKQ VLQLNRDSYP FEAGLELPFE MVTEVPIPRR PPPPQAANNT NSVSNNTNIQ  60
   61 FPDILSKASK HLPSFQDGSI IAPDKISQNL SKIPPLQLIE IISNLKILSN QENIQKSQLE 120
  121 SFLDTNSDIT ISVTQALLEM GFIDYSVVTK VLKSQVG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.6
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.74219150342477 bayes_pls_golite062009
nucleic acid binding 4.23531598582972 bayes_pls_golite062009
binding 4.00350364031155 bayes_pls_golite062009
mRNA binding 3.63162433534903 bayes_pls_golite062009
3.21905850396301 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.74537942253096 bayes_pls_golite062009
protein binding 1.26544376923141 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.19033433766236 bayes_pls_golite062009
single-stranded RNA binding 1.08300488237934 bayes_pls_golite062009
poly-pyrimidine tract binding 0.960399311787502 bayes_pls_golite062009
ligase activity 0.912895392833756 bayes_pls_golite062009
transcription factor activity 0.894914712180715 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.633093884585572 bayes_pls_golite062009
snRNA binding 0.448300421677168 bayes_pls_golite062009
sequence-specific DNA binding 0.238420044364247 bayes_pls_golite062009
mRNA 3'-UTR binding 0.229644510503376 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [261-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAPSLLSSNN TSNSNTPVSV IRNNTPLHVP SNEVSNNPNN MPLNVAMPMP MSTPPFIPLP  60
   61 LQQQPFGFAP PGPFMPPAQG PSMGQPVLAN QLGQVQQQNI SSTEGPSNAN KANDSGTINM 120
  121 AKLQLLPENQ QDMIKQVLTL TPAQIQSLPS DQQLMVENFR KEYII

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle