YRC Public Data Repository - Protein Structure Prediction

Protein:	TPC1
Organism:	Saccharomyces cerevisiae
Length:	314 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPC1.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-80	[5..311]	[183..470]
gi\|15620851 - gi\|15620851\|dbj\|BAB67789.1\| KIAA1896 protein [Homo sapiens]	1.0E-79	[5..308]	[274..560]
UCP3_BOVIN - Mitochondrial uncoupling protein 3 OS=Bos taurus GN=UCP3 PE=2 SV=1	3.0E-78	[7..313]	[4..302]
UCP3_PIG - Mitochondrial uncoupling protein 3 OS=Sus scrofa GN=UCP3 PE=2 SV=1	5.0E-78	[7..313]	[4..299]
UCP3_MOUSE - Mitochondrial uncoupling protein 3 OS=Mus musculus GN=Ucp3 PE=1 SV=1	1.0E-77	[13..313]	[10..299]
ADNT1_ARATH - Mitochondrial adenine nucleotide transporter ADNT1 OS=Arabidopsis thaliana GN=ADNT1 PE=2 SV=1	1.0E-77	[18..311]	[40..344]
gi\|151942810 - gi\|151942810\|gb\|EDN61156.1\| amino acid transporter [Saccharomyces cerevisiae YJM789] AGC1 - Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutama... AGC1_YEAST - Mitochondrial aspartate-glutamate transporter AGC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...	2.0E-77	[19..311]	[533..814]

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Predicted Domain #1

Region A:
Residues: [1-314]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKEEDSLRK GQNVAAWKTL LAGAVSGLLA RSITAPMDTI KIRLQLTPAN GLKPFGSQVM  60
   61 EVARSMIKNE GIRSFWKGNI PGSLLYVTYG SAQFSSYSLF NRYLTPFGLE ARLHSLVVGA 120
  121 FAGITSSIVS YPFDVLRTRL VANNQMHSMS ITREVRDIWK LEGLPGFFKG SIASMTTITL 180
  181 TASIMFGTYE TIRIYCDENE KTTAAHKKWE LATLNHSAGT IGGVIAKIIT FPLETIRRRM 240
  241 QFMNSKHLEK FSRHSSVYGS YKGYGFARIG LQILKQEGVS SLYRGILVAL SKTIPTTFVS 300
  301 FWGYETAIHY LRMY

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.04
Match:	1is2A
Description:	Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits