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View Structure Prediction Details

Protein: NNF2
Organism: Saccharomyces cerevisiae
Length: 936 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NNF2.

Description E-value Query
Range
Subject
Range
NNF2 - Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polyme...
NNF2_YEAST - Protein NNF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NNF2 PE=1 SV=1
0.0 [1..936] [1..936]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
3.0E-77 [154..933] [881..1670]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-77 [165..934] [896..1668]
MYH2_PIG - Myosin-2 OS=Sus scrofa GN=MYH2 PE=2 SV=1
gi|55741490 - ref|NP_999301.1| myosin heavy chain 2a [Sus scrofa]
7.0E-77 [173..934] [906..1670]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
1.0E-76 [164..934] [898..1671]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEQFTNQKK VSHLQSLMNT KRSEQPTEFA KKHRFKDTLA LFLVFLSFNH FTSLCLLVSF  60
   61 IVATKCKDFL ANCFIILFLS KKPSRHIGEV AHIDISTSKV TNGSSNRKSN SRFFGNSKNS 120
  121 FVIPIPVLIC EILFAMLLKI YGGDYFVKPI KNLAISIIAS FLINDPSDCL SYATSCSVLY 180
  181 AVSTNTFQRV SHFFDIIQLF DMSLRGTG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [209-589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSIKLFTVFR KYSQFFKKLF SLFLPMPFKM LGKHSDSMIY YLSFHILFFS FASSLLHPHR  60
   61 QTAENKPLKK GFNSTKPDVA RVQGLQKMRI SSSSSVSADS NTLEDQSPMI PNDPGGLSSS 120
  121 NQTIHPSQQN NSPVPLSSHS NILNPAASYP TDATSSFPYF TSMVKEYKSY QPSVISAEGS 180
  181 NSQAVTTTTS TTTSPTTFNF SGDNTSLSNE ISLSDSSNGN SKKDSDFFSP SNDKYTNQLF 240
  241 ELNVDFGNMF SSSKLSSDIS VTSNLENFIR LLFRRKNQHL IAPLWSMVVT LKTTNFEKKY 300
  301 LQETSENSLT PTNSNTSYVS NQEKHDKDLD TINTHSVSSR ISFTHAGKFK KSVFNNFEPS 360
  361 NTMALIAKTT SDDYNLLNLV S

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [590-657]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNENIFNRND NDYKVCIIDI STNSITFHIE NLHDGELIVL VNGVIWSEVS CALILEHVGE  60
   61 EYVVVNGL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [658-711]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPSCSYDIQF INRLNHRDDY LVSDLIVRTC GNNNAIAGKF ENLDFSFPSY YHRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.00940588691795 bayes_pls_golite062009
transcription regulator activity 0.516346942965208 bayes_pls_golite062009
nucleic acid binding 0.513833930010015 bayes_pls_golite062009
DNA binding 0.475884563138359 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [712-789]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLSPLLTLKH SVLTTNANLS DERTKLKKTK KEFSKKLSLL RQEIDYFKGR ISQNATHDEK  60
   61 STLKVENLKV ALQQSETA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [790-852]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNKLEMQLKT LTEKELELEE EYLKKKDLHL KNQLEFSKLE ESLSKDLKNS EGRFQKVNQE  60
   61 LVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [853-936]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSKLDKLNA RNEKLQKEVD QNAEEIEKFS TQFLSKREKD RFRRKEYRIR EANKFELTIK  60
   61 GLEQDINRLE NENENIHSLI GNSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.69897
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle