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View Structure Prediction Details

Protein: PEF1
Organism: Saccharomyces cerevisiae
Length: 335 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEF1.

Description E-value Query
Range
Subject
Range
PEF1 - Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc...
2.0E-93 [1..335] [1..335]
gi|5162882, gi|5... - gi|5162882|dbj|BAA81751.1| calcium-dependent protein kinase [Marchantia polymorpha], gi|5162878|dbj|...
1.0E-62 [100..298] [307..522]
CDPK6_ARATH - Calcium-dependent protein kinase 6 OS=Arabidopsis thaliana GN=CPK6 PE=1 SV=1
2.0E-62 [116..296] [345..523]
gi|16215471 - gi|16215471|emb|CAC82999.1| calcium-dependent protein kinase 3 [Nicotiana tabacum]
6.0E-62 [115..296] [373..552]
gi|19171502 - gi|19171502|emb|CAC87494.1| calcium-dependent protein kinase [Solanum lycopersicum]
7.0E-62 [117..299] [365..546]
gi|15289758 - gi|15289758|dbj|BAB63463.1| calcium dependent protein kinase [Solanum tuberosum]
9.0E-62 [115..296] [373..552]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCAKKLKYAA GDDFVRYATP KEAMEETRRE FEKEKQRQQQ IKVTQAQTPN TRVHSAPIPL  60
   61 QTQYNKNRAE NGHHSYGSPQ SYSPRHTKTP VDPRYNVIAQ KPAGRPIPPA PTHYNNLNTS 120
  121 AQRIASSPPP LIHNQAVPAQ LLKKVAPASF DSREDVRDMQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.519517
Match: 1juoA_
Description: Sorcin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [161-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VATQLFHNHD VKGKNRLTAE ELQNLLQNDD NSHFCISSVD ALINLFGASR FGTVNQAEFI  60
   61 ALYKRVKSWR KVYVDNDING SLTIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.519517
Match: 1juoA_
Description: Sorcin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [246-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEFHNSLQE LGYLIPFEVS EKTFDQYAEF INRNGTGKEL KFDKFVEALV WLMRLTKLFR  60
   61 KFDTNQEGIA TIQYKDFIYA TLYLGRFLPH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 179.68867
Match: 1hqvA_
Description: Apoptosis-linked protein alg-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
calcium ion binding 3.79609619542776 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
protein binding 2.21291432166051 bayes_pls_golite062009
cation binding 1.58747127156827 bayes_pls_golite062009
metal ion binding 1.58747127156827 bayes_pls_golite062009
ion binding 1.57990289083749 bayes_pls_golite062009
transcription regulator activity 0.450279748770607 bayes_pls_golite062009
nucleic acid binding 0.0981928858355918 bayes_pls_golite062009
DNA binding 0.0960817636106102 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle