YRC Public Data Repository - Protein Structure Prediction

Protein:	UGA1
Organism:	Saccharomyces cerevisiae
Length:	471 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UGA1.

Description	E-value	Query Range	Subject Range
gi\|4746, gi\|98626811 - gi\|98626811\|gb\|ABF58895.1\| GABA aminotransferase [Saccharomyces cerevisiae], gi\|4746\|emb\|CAA36833.1\|... gi\|151943304 - gi\|151943304\|gb\|EDN61617.1\| 4-aminobutyrate aminotransferase [Saccharomyces cerevisiae YJM789] gi\|207345227 - gi\|207345227\|gb\|EDZ72116.1\| YGR019Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190406953 - gi\|190406953\|gb\|EDV10220.1\| 4-aminobutyrate aminotransferase [Saccharomyces cerevisiae RM11-1a]	0.0	[1..471]	[1..471]
gi\|7471015 - pir\|\|G75595 4-aminobutyrate aminotransferase - Deinococcus radiodurans (strain R1) gi\|6460573, gi\|1... - gi\|6460573\|gb\|AAF12279.1\|AE001862_105 4-aminobutyrate aminotransferase [Deinococcus radiodurans R1],...	0.0	[10..471]	[6..453]
gi\|13540855, gi\|... - gi\|14324238\|dbj\|BAB59166.1\| 4-aminobutyrate aminotransferase [Thermoplasma volcanium GSS1], gi\|13540...	0.0	[21..469]	[14..446]
gi\|14600726, gi\|... - gi\|5104104\|dbj\|BAA79420.1\| class-III aminotransferase [Aeropyrum pernix K1], gi\|14600726\|ref\|NP_1472... gi\|7434127 - pir\|\|H72740 probable 4-aminobutyrate aminotransferase APE0457 - Aeropyrum pernix (strain K1)	0.0	[13..470]	[4..444]
gi\|16081241 - gi\|16081241\|ref\|NP_393547.1\| 4-aminobutyrate aminotransferase [Thermoplasma acidophilum DSM 1728] gi\|10639214 - gi\|10639214\|emb\|CAC11216.1\| L-2, 4-diaminobutyrate:2-ketoglutarate 4-aminotransferase related protei...	0.0	[21..470]	[14..447]
gi\|5457569, gi\|7... - pir\|\|E75201 pyridoxal phosphate-dependent aminotransferase PAB0086 - Pyrococcus abyssi (strain Orsay... gi\|14520354, gi\|... - gi\|5457569\|emb\|CAB49060.1\| Pyridoxal phosphate-dependent aminotransferase [Pyrococcus abyssi GE5], g...	0.0	[29..470]	[23..449]
OAT - ornithine aminotransferase gi\|114633242, gi... - gi\|114633244\|ref\|XP_001135280.1\| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes], gi\|114...	0.0	[6..468]	[18..436]
gi\|7434132 - pir\|\|A71016 probable 4-aminobutyrate aminotransferase - Pyrococcus horikoshii gi\|14591218, gi\|... - gi\|3257846\|dbj\|BAA30529.1\| 454aa long hypothetical 4-aminobutyrate aminotransferase [Pyrococcus hori...	0.0	[17..469]	[5..443]

Back

Predicted Domain #1

Region A:
Residues: [1-471]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSICEQYYPE EPTKPTVKTE SIPGPESQKQ LKELGEVFDT RPAYFLADYE KSLGNYITDV  60
   61 DGNTYLDLYA QISSIALGYN NPALIKAAQS PEMIRALVDR PALGNFPSKD LDKILKQILK 120
  121 SAPKGQDHVW SGLSGADANE LAFKAAFIYY RAKQRGYDAD FSEKENLSVM DNDAPGAPHL 180
  181 AVLSFKRAFH GRLFASGSTT CSKPIHKLDF PAFHWPHAEY PSYQYPLDEN SDANRKEDDH 240
  241 CLAIVEELIK TWSIPVAALI IEPIQSEGGD NHASKYFLQK LRDITLKYNV VYIIDEVQTG 300
  301 VGATGKLWCH EYADIQPPVD LVTFSKKFQS AGYFFHDPKF IPNKPYRQFN TWCGEPARMI 360
  361 IAGAIGQEIS DKKLTEQCSR VGDYLFKKLE GLQKKYPENF QNLRGKGRGT FIAWDLPTGE 420
  421 KRDLLLKKLK LNGCNVGGCA VHAVRLRPSL TFEEKHADIF IEALAKSVNE L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1210.0
Match:	1gtxA_
Description:	4-aminobutyrate aminotransferase, GABA-aminotransferase

Predicted functions:

Term	Confidence	Notes
4-aminobutyrate transaminase activity	9.08769857759091	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase binding	8.44659094913875	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	3.359406422625	bayes_pls_golite062009
transferase activity	2.59075614411581	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity	1.74778109525713	bayes_pls_golite062009
N-succinyltransferase activity	1.52003194822848	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.46601963907552	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.46601963907552	bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	1.4383564662931	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transferase activity, transferring acyl groups	1.19150094103499	bayes_pls_golite062009
transcription regulator activity	0.977210827616757	bayes_pls_golite062009
nucleic acid binding	0.892872530648552	bayes_pls_golite062009
binding	0.892049641082766	bayes_pls_golite062009
ligase activity	0.827063849687833	bayes_pls_golite062009
DNA binding	0.803965264969424	bayes_pls_golite062009
kynureninase activity	0.777830972119923	bayes_pls_golite062009
carbon-sulfur lyase activity	0.698312655247044	bayes_pls_golite062009
transcription factor activity	0.597417107954964	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.54326874956263	bayes_pls_golite062009
ornithine-oxo-acid transaminase activity	0.311107335626334	bayes_pls_golite062009
N-acyltransferase activity	0.2609065149092	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
cystathionine beta-lyase activity	0.15938456446406	bayes_pls_golite062009
hydrolase activity	0.158765164178244	bayes_pls_golite062009
amine binding	0.14702601411039	bayes_pls_golite062009
methyltransferase activity	0.103986924428507	bayes_pls_golite062009
sulfurtransferase activity	0.0450490929307473	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.0254276656964899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: