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View Structure Prediction Details

Protein: YGR017W
Organism: Saccharomyces cerevisiae
Length: 297 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGR017W.

Description E-value Query
Range
Subject
Range
YG1B_YEAST - Uncharacterized protein YGR017W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGR017W ...
YGR017W - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to bo...
0.0 [1..297] [1..297]
YGK3_SCHPO - Uncharacterized protein C725.03 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC725.03...
SPBC725.03 - conserved fungal protein
6.0E-39 [8..124] [5..136]
PPOX2_ARATH - Pyridoxine/pyridoxamine 5'-phosphate oxidase 2 OS=Arabidopsis thaliana GN=PPOX2 PE=1 SV=2
4.0E-37 [1..111] [1..95]
gi|17133171, gi|... - gi|17231528|ref|NP_488076.1| hypothetical protein alr4036 [Nostoc sp. PCC 7120], gi|17133171|dbj|BAB...
gi|25532479 - pir||AE2310 hypothetical protein alr4036 [imported] - Nostoc sp. (strain PCC 7120)
8.0E-32 [5..114] [3..96]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHQMAPWIP MFIQSCKNNT EPFVSFQFAT VDELTNKPRC RTVVFRDFLF HDKRTNVLTF  60
   61 NTDMRSSKIT ESFITPNSNN SSDSKRCETP FFEACFYFPE TWEQYRFSGQ CFTISKQFKK 120
  121 IPAEIVTKYD IFSPRFSETN DDSTDEEIDT PI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.85
Match: 1ci0A
Description: Pyridoxine 5'-phoshate oxidase (PNP oxidase)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [153-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDDDDDDKNN DADNNDINED NKLIESIEND EHHEDEDDYY PQPQEWEAEL LRQWSSLSRH  60
   61 TKSLYRKPAP GQKLTSETSK QLDKLHRGVD GAKEDAGLEN FGIVCLCVDS VDFLNLKEGR 120
  121 GGERWIFQKT DGKDEDLWEE QEVCP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.364 a.1.1 Globin-like
View Download 0.627 a.24.3 Cytochromes
View Download 0.425 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.353 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.322 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.297 a.48.2 Transferrin receptor ectodomain, C-terminal domain
View Download 0.295 a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.294 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.257 b.55.1 PH domain-like
View Download 0.241 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.234 a.1.1 Globin-like
View Download 0.223 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.220 a.24.17 Group V grass pollen allergen
View Download 0.200 a.18.1 T4 endonuclease V

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.32760581622259 bayes_pls_golite062009
binding 2.16870325397306 bayes_pls_golite062009
catalytic activity 0.636519364005912 bayes_pls_golite062009
transcription factor binding 0.397617773348741 bayes_pls_golite062009
protein binding 0.0480378028458218 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle