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View Structure Prediction Details

Protein: MUQ1
Organism: Saccharomyces cerevisiae
Length: 323 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUQ1.

Description E-value Query
Range
Subject
Range
MUQ1 - Choline phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosyn...
ECT1_YEAST - Ethanolamine-phosphate cytidylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
1.0E-99 [1..323] [1..323]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-99 [1..323] [1..323]
PCYT2 - phosphate cytidylyltransferase 2, ethanolamine
8.0E-95 [6..321] [21..365]
PCY2_MOUSE - Ethanolamine-phosphate cytidylyltransferase OS=Mus musculus GN=Pcyt2 PE=1 SV=1
2.0E-91 [5..321] [20..383]
PCY2_RAT - Ethanolamine-phosphate cytidylyltransferase OS=Rattus norvegicus GN=Pcyt2 PE=1 SV=1
5.0E-91 [5..321] [20..383]
PECT1_ARATH - Ethanolamine-phosphate cytidylyltransferase OS=Arabidopsis thaliana GN=PECT1 PE=1 SV=1
7.0E-84 [6..322] [53..407]
gi|13129435 - gi|13129435|gb|AAK13093.1| Putative phospholipid cytidylyltransferase [Oryza sativa (japonica cultiv...
gi|37533878, gi|... - gi|37533878|ref|NP_921241.1| putative phospholipid cytidylyltransferase [Oryza sativa (japonica cult...
3.0E-83 [2..312] [407..738]
ECT1_SCHPO - Probable ethanolamine-phosphate cytidylyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC...
SPAC15E1.05c - ethanolamine-phosphate cytidylyltransferase
2.0E-74 [9..319] [10..350]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVNLDPDKV WIDGCFDFTH HGHAGAILQA RRTVSKENGK LFCGVHTDED IQHNKGTPVM  60
   61 NSSERYEHTR SNRWCSEVVE AAPYVTDPNW MDKYQCQYVV HGDDITIDAN GEDCYKLVKE 120
  121 MGRFKVVKRT YGVSTTEIIH RILTKKSLPP THPDYYPTTQ ELSFYSVAQD AVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.69897
Match: 1cozA_
Description: CTP:glycerol-3-phosphate cytidylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-oxygen bonds 3.78648093277891 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.78648093277891 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 3.77519125450118 bayes_pls_golite062009
ligase activity 2.86871261550755 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
ethanolamine-phosphate cytidylyltransferase activity 2.31031486896772 bayes_pls_golite062009
glutamate-tRNA ligase activity 0.993808666373194 bayes_pls_golite062009
nucleotidyltransferase activity 0.427749234863188 bayes_pls_golite062009
binding 0.419067006588658 bayes_pls_golite062009
methionine-tRNA ligase activity 0.376417381080717 bayes_pls_golite062009
nucleic acid binding 0.311743335409574 bayes_pls_golite062009
tyrosine-tRNA ligase activity 0.257183459378457 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.097721445469396 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [174-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHCYVFQRDL DNVLVNGGYK FDAEDCVYVD GDFDLFHMGD IDQLRKLKMD LHPDKKLIVG  60
   61 ITTSDYSSTI MTMKERVLSV LSCKYVDAVI IDADATSMSQ YNCEKYHIGT AVLTAAGKFS 120
  121 EYLTKELIVK RVESQREVYI ARNQKKGMSI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.045757
Match: 1b6tA_
Description: Phosphopantetheine adenylyltransferase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle