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Protein Overview: PCYT2

General Information:
Name(s) found: PCYT2 [HGNC (HUGO)]
Description(s) found:
Found 29 descriptions.
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  • phosphate cytidylyltransferase 2, ethanolamine [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 389 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRNGRGAAG GAEQPGPGGR RAVRVWCDGC YDMVHYGHSN QLRQARAMGD YLIVGVHTDE  60
   61 EIAKHKGPPV FTQEERYKMV QAIKWVDEVV PAAPYVTTLE TLDKYNCDFC VHGNDITLTV 120
  121 DGRDTYEEVK QAGRYRECKR TQGVSTTDLV GRMLLVTKAH HSSQEMSSEY REYADSFGKC 180
  181 PGGRNPWTGV SQFLQTSQKI IQFASGKEPQ PGETVIYVAG AFDLFHIGHV DFLEKVHRLA 240
  241 ERPYIIAGLH FDQEVNHYKG KNYPIMNLHE RTLSVLACRY VSEVVIGAPY AVTAELLSHF 300
  301 KVDLVCHGKT EIIPDRDGSD PYQEPKRRGI FRQIDSGSNL TTDLIVQRII TNRLEYEARN 360
  361 QKKEAKELAF LEAARQQAAQ PLGERDGDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..163] PSI-BLAST 32.39794 CTP:glycerol-3-phosphate cytidylyltransferase
    2 View Details [164..389] PSI-BLAST 9.0 Crystal structure of a flavin binding protein from Thermotoga Maritima, TM379

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  3.78648093277891 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  3.78648093277891 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  3.77519125450118 bayes_pls_golite062009
  • ligase activity
    		•  2.69963581983481 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • ethanolamine-phosphate cytidylyltransferase activity
    		•  2.31031486896772 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  0.993808666373194 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.911644628339304 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.774843857641774 bayes_pls_golite062009
  • binding
    		•  0.520077014845626 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.427749234863188 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.42131487486996 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  0.376417381080717 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  0.257183459378457 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle