| Protein: | TOS3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 560 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOS3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [49..544] | [18..467] |
|
|
0.0 | [1..560] | [1..560] |
|
|
0.0 | [47..523] | [14..433] |
|
|
0.0 | [46..538] | [15..463] |
|
|
0.0 | [46..498] | [16..416] |
|
|
0.0 | [53..538] | [1..432] |
|
|
0.0 | [49..520] | [7..421] |
|
Region A: Residues: [1-41] |
1 11 21 31 41 51
| | | | | |
1 MVLLKEPVQP LPRSSLLYNN ASNSSSRIKE TRKVKLLYNP L
|
|
Region B: Residues: [97-119] |
1 11 21 31 41 51
| | | | | |
1 ENPRVNQEIE VMKRCHHENV VEL
|
|
Region C: Residues: [137-390] |
1 11 21 31 41 51
| | | | | |
1 YCSRGPVKWC PENKMEIKAV GPSILTFQQS RKVVLDVVSG LEYLHSQGIT HRDIKPSNLL 60
61 ISSNGTVKIS DFGVAMSTAT GSTNIQSSHE QLLKSRALGT PAFFAPELCS TEKEYSCSSA 120
121 IDIWSLGVTI YCLLFGKLPF NANSGLELFD SIINKPLEFP SYEEMLNGAT SGITMEEYTD 180
181 AKDLLKKLLQ KDPDKRIKLA DIKVHPFMCH YGKSDAASVL TNLETFHELK VSPPSSCKRV 240
241 ELVSLPVNSS FASL
|
| Detection Method: |  |
| Confidence: | 380.0 |
| Match: | 1ctpE_ |
| Description: | cAMP-dependent PK, catalytic subunit |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.17195961442593 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.46123870227889 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| binding | 2.31930216202447 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.282849280638519 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
|
Region A: Residues: [42-96] |
1 11 21 31 41 51
| | | | | |
1 TKRQILNNFE ILATLGNGQY GKVKLARDLG TGALVAIKIL NRFEKRSGYS LQLKV
|
|
Region B: Residues: [120-136] |
1 11 21 31 41 51
| | | | | |
1 YEILNDPEST KVYLVLE
|
|
Region C: Residues: [391-439] |
1 11 21 31 41 51
| | | | | |
1 DSVYMENFDH NNLRTGADRN STYSPSIYDA NTLSPSAYHN IGSRESSYS
|
| Detection Method: | |
| Confidence: | 380.0 |
| Match: | 1ctpE_ |
| Description: | cAMP-dependent PK, catalytic subunit |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [440-560] |
1 11 21 31 41 51
| | | | | |
1 SFSSFTSSTA FASQISIQDA PAIGDQQCLI GESGSSLRVN SCEFPQYTTM SPVGEYPFES 60
61 TEASLSSTLT PVGNVPQRIK AHLVEGKSNS KDDLRIEADA SLVFEASDAQ RTRRRMSLYK 120
121 L
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.312 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.328 | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.324 | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.362 | d.74.5 | Hypothetical protein Yml108w |
| View | Download | 0.344 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.298 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.293 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.251 | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.249 | b.34.9 | Tudor/PWWP/MBT |
| View | Download | 0.246 | a.74.1 | Cyclin-like |
| View | Download | 0.231 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.229 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.226 | b.2.3 | Bacterial adhesins |
| View | Download | 0.221 | d.185.1 | LuxS/MPP-like metallohydrolase |
| View | Download | 0.209 | d.163.1 | DNA breaking-rejoining enzymes |
| View | Download | 0.203 | a.81.1 | N-terminal domain of DnaB helicase |
