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View Structure Prediction Details

Protein: ROK1
Organism: Saccharomyces cerevisiae
Length: 564 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ROK1.

Description E-value Query
Range
Subject
Range
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [2..510] [65..579]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [2..511] [108..621]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [2..510] [65..579]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..510] [65..579]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [2..511] [108..621]
gi|10039327 - gi|10039327|dbj|BAB13306.1| PL10-related protein CnPL10 [Hydra magnipapillata]
0.0 [16..552] [62..611]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIFRVLTRG ASVKKESGPK AKAADYSVIN GNDENHKEDN NESQIVKELD FFRNKRIISK  60
   61 VEDDREKTTE NDSPNKEEKS GNDDGLIKPV ITNTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.471 a.39.1 EF-hand
View Download 0.201 a.5.6 Hypothetical protein MTH1615
View Download 0.471 a.39.1 EF-hand
View Download 0.201 a.5.6 Hypothetical protein MTH1615

Predicted Domain #2
Region A:
Residues: [96-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EASALRKSYK GNVSGIDIPL PIGSFEDLIS RFSFDKRLLN NLIENGFTEP TPIQCECIPV  60
   61 ALNNRDVLAC GPTGSGKTLA FLIPLVQQII DDKQTAGLKG LIISPTKELA NQIFIECFKL 120
  121 SYKIFLEKKR PLQVALLSKS LGAKLKNKVV SDKKYDIIIS TPLRLIDVVK NEALDLSKVK 180
  181 HLIFDEADKL FDKTFVEQSD DILSACREPS LRKAMFSATI PSNVEEIAQS IMMDPVRVII 240
  241 GHKEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 539.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [341-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANTNIEQKLI FCGNEEGKLI AIRQLVQEGE FKPPIIIFLE SITRAKALYH ELMYDRINVD  60
   61 VIHAERTALQ RDRIIERFKT GELWCLICTD VLARGIDFKG VNLVINYDVP GSSQAYVHRI 120
  121 GRTGRGGRSG KAITFYTKQD SVAIKPIINV MKQSGCE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 539.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [498-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEWMDKMAK MTRKEKESIK NGKAHKERKQ ITTVPKMDKA KRRRQQEMIA ASKRRKNEEL  60
   61 SKKHFSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.528 0.001 nucleolus a.4.5 "Winged helix" DNA-binding domain
View Download 0.696 0.001 nucleolus a.4.1 Homeodomain-like
View Download 0.617 0.001 nucleolus a.77.1 DEATH domain
View Download 0.950 0.001 nucleolus a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.406 0.001 nucleolus a.64.1 Saposin
View Download 0.394 0.001 nucleolus a.4.5 "Winged helix" DNA-binding domain
View Download 0.377 0.001 nucleolus a.4.5 "Winged helix" DNA-binding domain
View Download 0.369 0.001 nucleolus a.36.1 Signal peptide-binding domain
View Download 0.369 0.001 nucleolus a.4.1 Homeodomain-like
View Download 0.365 0.001 nucleolus a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.361 0.001 nucleolus a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.345 0.001 nucleolus a.60.11 Hypothetical protein YjbJ
View Download 0.342 0.001 nucleolus a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.335 0.001 nucleolus a.60.12 DNA polymerase beta-like, second domain
View Download 0.327 0.001 nucleolus a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.319 0.001 nucleolus a.64.1 Saposin
View Download 0.302 0.001 nucleolus a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.298 0.001 nucleolus a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.297 0.001 nucleolus a.24.17 Group V grass pollen allergen
View Download 0.279 0.001 nucleolus a.4.1 Homeodomain-like
View Download 0.270 0.001 nucleolus a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.269 0.001 nucleolus a.4.11 RNA polymerase subunit RPB10
View Download 0.265 0.001 nucleolus a.159.2 FF domain
View Download 0.261 0.001 nucleolus a.4.5 "Winged helix" DNA-binding domain
View Download 0.260 0.001 nucleolus a.39.1 EF-hand
View Download 0.255 0.001 nucleolus a.112.1 Description not found.
View Download 0.253 0.001 nucleolus a.39.1 EF-hand
View Download 0.251 0.001 nucleolus a.4.1 Homeodomain-like
View Download 0.246 0.001 nucleolus a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.236 0.001 nucleolus a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.231 0.001 nucleolus a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.231 0.001 nucleolus a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.227 0.001 nucleolus a.4.5 "Winged helix" DNA-binding domain
View Download 0.221 0.001 nucleolus a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.216 0.001 nucleolus a.60.1 SAM/Pointed domain
View Download 0.211 0.001 nucleolus a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.207 0.001 nucleolus a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.205 0.001 nucleolus a.4.2 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
View Download 0.202 0.001 nucleolus a.65.1 Annexin
View Download 0.201 0.001 nucleolus a.4.3 ARID-like


YRC Informatics Platform - Version 3.0
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