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View Structure Prediction Details

Protein: ROK1
Organism: Saccharomyces cerevisiae
Length: 564 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ROK1.

Description E-value Query
Range
Subject
Range
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [2..510] [65..579]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [2..511] [108..621]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [2..510] [65..579]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..510] [65..579]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [2..511] [108..621]
gi|10039327 - gi|10039327|dbj|BAB13306.1| PL10-related protein CnPL10 [Hydra magnipapillata]
0.0 [16..552] [62..611]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIFRVLTRG ASVKKESGPK AKAADYSVIN GNDENHKEDN NESQIVKELD FFRNKRIISK  60
   61 VEDDREKTTE NDSPNKEEKS GNDDGLIKPV ITNTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EASALRKSYK GNVSGIDIPL PIGSFEDLIS RFSFDKRLLN NLIENGFTEP TPIQCECIPV  60
   61 ALNNRDVLAC GPTGSGKTLA FLIPLVQQII DDKQTAGLKG LIISPTKELA NQIFIECFKL 120
  121 SYKIFLEKKR PLQVALLSKS LGAKLKNKVV SDKKYDIIIS TPLRLIDVVK NEALDLSKVK 180
  181 HLIFDEADKL FDKTFVEQSD DILSACREPS LRKAMFSATI PSNVEEIAQS IMMDPVRVII 240
  241 GHKEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 539.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [341-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANTNIEQKLI FCGNEEGKLI AIRQLVQEGE FKPPIIIFLE SITRAKALYH ELMYDRINVD  60
   61 VIHAERTALQ RDRIIERFKT GELWCLICTD VLARGIDFKG VNLVINYDVP GSSQAYVHRI 120
  121 GRTGRGGRSG KAITFYTKQD SVAIKPIINV MKQSGCE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 539.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [498-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEWMDKMAK MTRKEKESIK NGKAHKERKQ ITTVPKMDKA KRRRQQEMIA ASKRRKNEEL  60
   61 SKKHFSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.950 0.001 nucleolus a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle