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View Structure Prediction Details

Protein: SCY1
Organism: Saccharomyces cerevisiae
Length: 804 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCY1.

Description E-value Query
Range
Subject
Range
SCY1 - Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase
SCY1_YEAST - Protein kinase-like protein SCY1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SCY1 PE...
0.0 [1..804] [1..804]
SCYL1 - SCY1-like 1 (S. cerevisiae)
0.0 [16..764] [18..689]
gi|2462837, gi|2... - pir||F86362 F19G10.17 protein - Arabidopsis thaliana, gi|2462837|gb|AAB72172.1| hypothetical protei...
0.0 [144..798] [1..669]
NTKL_MOUSE - N-terminal kinase-like protein OS=Mus musculus GN=Scyl1 PE=1 SV=1
0.0 [15..763] [17..687]
PPK32_SCHPO - Protein kinase domain-containing protein ppk32 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
ppk32 - serine /threonine protein kinase Ppk32
0.0 [1..780] [6..748]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMFWSSKTGI TSKYSFSSSP TFTAEPWSIY TGRPKSSSSS SPSKVSIFMF DKKQFENYLL  60
   61 HYGIIKSKSG SRDKVLIQEA YEILRNQA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [102-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIEPLEEHSK NFMFVTE

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [345-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKYVFLEGLV NLLPEFPPAL LQKKFLPILL ELLSQFCAEK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 157.0
Match: 1fotA_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [89-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNLAKLKHPN ILT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [119-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVTSSLETVF RETDDEEQNF LQGHVKDNIV VQRGILQLVN ALDFVHNRAS FVHLNIQPRA  60
   61 IFINENSDWK ISGLGYLVKI PPGTNTSEYF LPQYDPRVPP FMHLQLNYTA PEIVFENTLT 120
  121 FKNDYFSLGL LIYFLYTGKD LFRSENSTSE YKLEYNKFES KISTMSWDNI FSKVPQKLRH 180
  181 CIPKLINRDI YSRYDNITLI LDSEFFQDPL VKTLNFLDDL PTKNNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 157.0
Match: 1fotA_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [385-573]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVSDKCVGKS LDLIIKIGST LSQLSFQEKV YPVLLSDANF PVLLKKATIC LIDNLDTLKQ  60
   61 KVKRSDFLEN ILKPLFNYVL HDSESDITVV CQEKLLSQIP LALEVLDFPT VKQFLLPLLS 120
  121 NLFTKTTSLT VKNTCVTCFQ IMIEHKSIDS YTCSETVLPL FKSMKTRDPR ILSKLLKLFE 180
  181 TVPLIITDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1b3uA_
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [574-804]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVLVDQVLPL MWNYSMASTL TKSQYSGYTK AINKMSSDIQ KHHIAKLDDK VNDIGEDAFH  60
   61 KVIEPTIMKK EDPETVAAKN IEVAAMQPVK KKTGSSYGET LPQSKSILNS KPLNPKNALA 120
  121 TRGFPTRILN SPPQTPSSRT GSKVMTKGGS NDASSTKVEE EFNEFQSFSS TGSIRQTSAP 180
  181 SDVWMNSTPS PTPTSASSTN LPPGFSISLQ PNKRKDGSSD IPRSNVYGSL I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle