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View Structure Prediction Details

Protein: RNA15
Organism: Saccharomyces cerevisiae
Length: 296 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNA15.

Description E-value Query
Range
Subject
Range
ELAVL2 - ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
3.0E-55 [2..274] [24..272]
IPI:IPI00192584.... - Tax_Id=10116 RNA binding protein HuB
ELAV2_MOUSE - ELAV-like protein 2 OS=Mus musculus GN=Elavl2 PE=2 SV=1
4.0E-54 [2..274] [24..273]
gi|5739519, gi|4... - gi|5739519|gb|AAD50508.1|AF176675_1 RNA-binding protein HuD [Gallus gallus], gi|45382273|ref|NP_9901...
6.0E-54 [2..273] [35..283]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-53 [2..273] [30..278]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRQSGVNAG VQNNPPSRVV YLGSIPYDQT EEQILDLCSN VGPVINLKMM FDPQTGRSKG  60
   61 YAFIEFRDLE SSASAVRNLN GYQLGSRFLK CGYSSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.9897
Match: 1fxlA_
Description: Hu antigen D (Hud)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
3.4479220904723 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 1.36691748240059 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
snRNA binding 0.73428616955527 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [97-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDISGVSQQQ QQQYNNINGN NNNNGNNNNN SNGPDFQNSG NANFLSQKFP ELPSGIDVNI  60
   61 NMTTPAMMIS SELAKKPKEV QLKFLQKFQE WTRAHPEDAV SLLELC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.9897
Match: 1fxlA_
Description: Hu antigen D (Hud)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.11788426448287 bayes_pls_golite062009
mRNA binding 4.06818972936809 bayes_pls_golite062009
single-stranded RNA binding 3.03728178586535 bayes_pls_golite062009
nucleic acid binding 2.68703240185319 bayes_pls_golite062009
poly(A) RNA binding 2.66269581586161 bayes_pls_golite062009
poly-purine tract binding 2.20136693536924 bayes_pls_golite062009
binding 2.16883445607402 bayes_pls_golite062009
eukaryotic initiation factor 4G binding 2.1187709602541 bayes_pls_golite062009
catalytic activity 0.287695754348243 bayes_pls_golite062009
protein self-association 0.283882327957323 bayes_pls_golite062009
protein binding 0.159640166509248 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.04158498339604 bayes_pls_golite062009
small conjugating protein ligase activity 0.0311121204326499 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [203-296]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQLSFVTAEL LLTNGICKVD DLIPLASRPQ EEASATNNNS VNEVVDPAVL NKQKELLKQV  60
   61 LQLNDSQISI LPDDERMAIW DLKQKALRGE FGAF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1g9lA_
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle