YRC Public Data Repository - Protein Structure Prediction

Protein:	PNC1
Organism:	Saccharomyces cerevisiae
Length:	216 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNC1.

Description	E-value	Query Range	Subject Range
gi\|13361942, gi\|... - gi\|15831729\|ref\|NP_310502.1\| hypothetical protein ECs2475 [Escherichia coli O157:H7], gi\|13361942\|db... gi\|209768360, gi... - pir\|\|G85786 hypothetical protein ydjB [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12515794, gi\|... - gi\|15802180\|ref\|NP_288202.1\| hypothetical protein Z2802 [Escherichia coli O157:H7 EDL933], gi\|125157... gi\|13361942, gi\|... - gi\|15831729\|ref\|NP_310502.1\| hypothetical protein ECs2475 [Escherichia coli O157:H7 str. Sakai], gi\|...	1.0E-55	[2..213]	[10..208]
gi\|188487756, gi... - gi\|188492557\|ref\|ZP_02999827.1\| pyrazinamidase/nicotinamidase [Escherichia coli 53638], gi\|188487756... gi\|194422494, gi... - gi\|194438484\|ref\|ZP_03070573.1\| pyrazinamidase/nicotinamidase [Escherichia coli 101-1], gi\|194422494... gi\|254161826, gi... - gi\|254161826\|ref\|YP_003044934.1\| nicotinamidase/pyrazinamidase [Escherichia coli B str. REL606], gi\|... EG11135 - nicotinamidase /pyrazinamidase / Pyrazinamidase /nicotinamidase gi\|169889260, gi... - gi\|170081425\|ref\|YP_001730745.1\| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr. D... EG11135 - nicotinamidase /pyrazinamidase / Pyrazinamidase /nicotinamidase gi\|251785216, gi... - gi\|251785216\|ref\|YP_002999520.1\| hypothetical protein B21_01725 [Escherichia coli BL21], gi\|24237748... gi\|253324321, gi... - gi\|254288614\|ref\|YP_003054362.1\| nicotinamidase/pyrazinamidase [Escherichia coli BL21(DE3)], gi\|2539... PNCA_ECOLI - Pyrazinamidase/nicotinamidase (EC 3.5.1.-) (EC 3.5.1.19) (PZAase) (Nicotine deamidase) (NAMase) - Es... gi\|89108607, gi\|... - gi\|89108607\|ref\|AP_002387.1\| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr. W3110... gi\|157066910, gi... - gi\|157161230\|ref\|YP_001458548.1\| nicotinamidase/pyrazinamidase [Escherichia coli HS], gi\|157066910\|g... gi\|238861893, gi... - gi\|238900982\|ref\|YP_002926778.1\| nicotinamidase/pyrazinamidase [Escherichia coli BW2952], gi\|2388618...	3.0E-55	[2..213]	[4..202]
gi\|17986829, gi\|... - gi\|17986829\|ref\|NP_539463.1\| pyrazinamidase / nicotinamidase [Brucella melitensis 16M], gi\|17982463\|... gi\|25527673 - pir\|\|AD3320 nicotinamidase (EC 3.5.1.19) [imported] - Brucella melitensis (strain 16M)	8.0E-53	[3..216]	[47..243]
gi\|167420273, gi... - gi\|167420273\|ref\|ZP_02312026.1\| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis str... gi\|167054443, gi... - gi\|167426567\|ref\|ZP_02318320.1\| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Mediaevalis st... gi\|167470631 - gi\|167470631\|ref\|ZP_02335335.1\| pyrazinamidase/nicotinamidase [Yersinia pestis FV-1] gi\|165912682, gi... - gi\|89101589\|ref\|ZP_01174316.1\| COG1335: Amidases related to nicotinamidase [Yersinia pestis biovar O... gi\|108807513, gi... - gi\|108807513\|ref\|YP_651429.1\| nicotinamidase/pyrazinamidase [Yersinia pestis Antiqua], gi\|108779426\|... gi\|165920307, gi... - gi\|165927693\|ref\|ZP_02223525.1\| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis str... gi\|108775437, gi... - gi\|229902084\|ref\|ZP_04517205.1\| nicotinamidase and pyrazinamidase [Yersinia pestis Nepal516], gi\|229... gi\|165991868, gi... - gi\|166009313\|ref\|ZP_02230211.1\| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str. E... gi\|149292330, gi... - gi\|149365917\|ref\|ZP_01887952.1\| putative pyrazinamidase/nicotinamidase [Yersinia pestis CA88-4125], ... gi\|166211140, gi... - gi\|166211140\|ref\|ZP_02237175.1\| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str. B... gi\|162351481, gi... - gi\|77634445\|ref\|ZP_00796545.1\| COG1335: Amidases related to nicotinamidase [Yersinia pestis Angola],... gi\|145598271, gi... - gi\|145598271\|ref\|YP_001162347.1\| nicotinamidase/pyrazinamidase [Yersinia pestis Pestoides F], gi\|145... gi\|167401379, gi... - gi\|167401379\|ref\|ZP_02306876.1\| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str. U... gi\|229894834, gi... - gi\|229894834\|ref\|ZP_04510014.1\| nicotinamidase and pyrazinamidase [Yersinia pestis Pestoides A], gi\|... gi\|229693915, gi... - gi\|229897578\|ref\|ZP_04512734.1\| nicotinamidase and pyrazinamidase [Yersinia pestis biovar Orientalis... gi\|25302276 - pir\|\|AD0263 nicotinamidase (EC 3.5.1.19) [imported] - Yersinia pestis (strain CO92) gi\|229898223, gi... - gi\|229898223\|ref\|ZP_04513371.1\| nicotinamidase and pyrazinamidase [Yersinia pestis biovar Orientalis... gi\|45441761, gi\|... - gi\|45441761\|ref\|NP_993300.1\| nicotinamidase/pyrazinamidase [Yersinia pestis biovar Microtus str. 910... gi\|21959002, gi\|... - gi\|22126050\|ref\|NP_669473.1\| nicotinamidase/pyrazinamidase [Yersinia pestis KIM], gi\|21959002\|gb\|AAM... gi\|15980164, gi\|... - gi\|218929260\|ref\|YP_002347135.1\| nicotinamidase/pyrazinamidase [Yersinia pestis CO92], gi\|16122392\|r...	6.0E-52	[3..214]	[4..202]
gi\|16419810, gi\|... - gi\|16764644\|ref\|NP_460259.1\| nicotinamidase/pyrazinamidase [Salmonella typhimurium LT2], gi\|16419810... gi\|197241232, gi... - gi\|197262977\|ref\|ZP_03163051.1\| pyrazinamidase/nicotinamidase [Salmonella enterica subsp. enterica s... gi\|198244735, gi... - gi\|198244735\|ref\|YP_002215833.1\| pyrazinamidase/nicotinamidase [Salmonella enterica subsp. enterica ... gi\|205329810, gi... - gi\|205329810\|gb\|EDZ16574.1\| pyrazinamidase/nicotinamidase [Salmonella enterica subsp. enterica serov... lcl\|NC_016856.1_... - [gene=pncA] [protein=nicotinamidase/pyrazinamidase] [protein_id=YP_005237145.1] [location=complement...	7.0E-52	[2..213]	[4..202]
gi\|197362644, gi... - gi\|197362644\|ref\|YP_002142281.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica ... gi\|16760602 - gi\|16760602\|ref\|NP_456219.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica sero... gi\|213162981 - gi\|213162981\|ref\|ZP_03348691.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica s... gi\|213427775 - gi\|213427775\|ref\|ZP_03360525.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica s... gi\|25302277, gi\|... - gi\|25302277\|pir\|\|AD0711 pyrazinamidase/nicotinamidase (EC 3.5.1.-) [imported] - Salmonella enterica ... gi\|213609515 - gi\|213609515\|ref\|ZP_03369341.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica s... gi\|29137266, gi\|... - gi\|29141638\|ref\|NP_804980.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica sero... gi\|213647251 - gi\|213647251\|ref\|ZP_03377304.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica s... gi\|56127978, gi\|... - gi\|56413721\|ref\|YP_150796.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica sero... gi\|213850389 - gi\|213850389\|ref\|ZP_03381287.1\| nicotinamidase/pyrazinamidase [Salmonella enterica subsp. enterica s...	1.0E-51	[2..213]	[4..202]
gi\|151943253 - gi\|151943253\|gb\|EDN61566.1\| nicotinamidase [Saccharomyces cerevisiae YJM789] PNC1 - Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, r... PNC1_YEAST - Nicotinamidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PNC1 PE=1 SV=1	1.0E-51	[1..216]	[1..216]
gi\|15073509, gi\|... - gi\|8571421\|gb\|AAF76877.1\|AF247710_2 putative pyrazinamidase/nicotinamidase PncA [Sinorhizobium melil... gi\|15964332 - gi\|15964332\|ref\|NP_384685.1\| pyrazinamidase/nicotinamidase (Includes: pyrazinamidase, nicotinamidase...	6.0E-51	[2..214]	[16..211]
gi\|13474085, gi\|... - gi\|14024837\|dbj\|BAB51439.1\| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099], gi\|134740...	9.0E-49	[3..215]	[5..200]
gi\|25302280 - pir\|\|H97607 hypothetical protein AGR_C_3739 [imported] - Agrobacterium tumefaciens (strain C58, Cere... gi\|15157195, gi\|... - gi\|15889351\|ref\|NP_355032.1\| hypothetical protein AGR_C_3739 [Agrobacterium tumefaciens str. C58], g...	4.0E-47	[1..214]	[18..217]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLIVVDMQ NDFISPLGSL TVPKGEELIN PISDLMQDAD RDWHRIVVTR DWHPSRHISF  60
   61 AKNHKDKEPY STYTYHSPRP GDDSTQEGIL WPVHCVKNTW GSQLVDQIMD QVVTKHIKIV 120
  121 DKGFLTDREY YSAFHDIWNF HKTDMNKYLE KHHTDEVYIV GVALEYCVKA TAISAAELGY 180
  181 KTTVLLDYTR PISDDPEVIN KVKEELKAHN INVVDK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	312.9897
Match:	1ilwA_
Description:	Pyrazinamidase/nicotinamidase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits