| Protein: | IRC5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 778 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IRC5.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [22..770] | [15..703] |
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0.0 | [18..749] | [413..1109] |
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0.0 | [34..758] | [15..736] |
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0.0 | [45..775] | [2..794] |
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0.0 | [34..777] | [362..1096] |
|
Region A: Residues: [1-68] |
1 11 21 31 41 51
| | | | | |
1 MSRCSNAALM TVVEDAVGAR VAARTRNMSN GVNYREKEVN DLTADISDSD SDLDSEDNKH 60
61 GKGDNDTA
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.667 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.435 | d.42.1 | POZ domain |
| View | Download | 0.428 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.430 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.425 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.361 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.359 | a.2.7 | tRNA-binding arm |
| View | Download | 0.349 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.343 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.324 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.315 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.306 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.294 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.289 | a.2.4 | Theta subunit of DNA polymerase III |
| View | Download | 0.266 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.262 | a.135.1 | Tetraspanin |
| View | Download | 0.259 | a.42.1 | MDM2 |
| View | Download | 0.254 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.253 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.230 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.218 | a.3.1 | Cytochrome c |
| View | Download | 0.215 | a.55.1 | IHF-like DNA-binding proteins |
| View | Download | 0.205 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.204 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.204 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.200 | d.29.1 | Ribosomal protein L31e |
|
Region A: Residues: [69-162] |
1 11 21 31 41 51
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1 PIWLQDDVHS DEDIQLDSED DSDTEAVQAQ VVDKLAKDTK SEQKSLDDEL SEMDTKTVSL 60
61 KLKKLNEFVR QSQVYSSIIA DTLLHRSNEV ANAN
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| Detection Method: | |
| Confidence: | 25.66807 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [163-422] |
1 11 21 31 41 51
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1 TKDNSNSDDE EHSSKKRKTK KKSITDFFKK QKKNEDTTTQ NGAPDDAAIK QPRLLKNCIL 60
61 KPYQLEGLNW LITLYENGLN GILADEMGLG KTVQSIALLA FIYEMDTKGP FLVTAPLSTL 120
121 DNWMNEFAKF APDLPVLKYY GTNGYKERSA KLKNFFKQHG GTGIVITSYE IILRDTDLIM 180
181 SQNWKFLIVD EGHRLKNINC RLIKELKKIN TSNRLLLTGT PLQNNLAELW SLLNFIMPDI 240
241 FADFEIFNKW FDFDSLNLGS
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| Detection Method: | |
| Confidence: | 25.66807 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [423-478] |
1 11 21 31 41 51
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1 GSNSEALNKL INDELQKNLI SNLHTILKPF LLRRLKKVVL ANILPPKREY IINCPM
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.603 | a.4.1 | Homeodomain-like |
| View | Download | 0.496 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.470 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.552 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.442 | d.58.17 | Metal-binding domain |
| View | Download | 0.404 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.395 | a.74.1 | Cyclin-like |
| View | Download | 0.387 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.383 | a.30.1 | ROP protein |
| View | Download | 0.374 | g.58.1 | Pheromone ER-23 |
| View | Download | 0.367 | a.4.1 | Homeodomain-like |
| View | Download | 0.321 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.308 | a.4.1 | Homeodomain-like |
| View | Download | 0.306 | a.4.1 | Homeodomain-like |
| View | Download | 0.305 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.275 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.271 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.247 | a.178.1 | Soluble domain of poliovirus core protein 3a |
| View | Download | 0.233 | a.4.1 | Homeodomain-like |
| View | Download | 0.228 | d.15.3 | MoaD/ThiS |
| View | Download | 0.225 | a.112.1 | Description not found. |
| View | Download | 0.219 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.217 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.208 | a.164.1 | C-terminal domain of DFF45/ICAD (DFF-C domain) |
| View | Download | 0.203 | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
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Region A: Residues: [479-778] |
1 11 21 31 41 51
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1 TSAQEKFYKA GLNGKLKKTM FKELIKDFFT LNDEYIGHVS NRSIRDFINY KLSGNETSNT 60
61 DNKINPTLLQ MDKLYKKNLQ MEISNKKLQN MMMQLRQIID STFLFYFPYL HPEDLTLETL 120
121 LKTSGKLQIL QKLIPPLISE GHKVLIYSQF VNMLDLIEDW CDLNSFATFR IDGSVNNETR 180
181 KDQLEKFNSS KDKHNIFLLS TRAAGLGINL VGADTVVLFD SDWNPQVDLQ AMDRCHRIGQ 240
241 ESPVIVYRLC CDNTIEHVIL TRAANKRNLE RMVIQMGKFN NLKKLALNEG FFFEGKQSGC 300
301
|
| Detection Method: | |
| Confidence: | 11.0 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
Matching Structure (courtesy of the PDB): |
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