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View Structure Prediction Details

Protein: YFR018C
Organism: Saccharomyces cerevisiae
Length: 363 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFR018C.

Description E-value Query
Range		 Subject
Range
YFR018C - Putative protein of unknown function
YFI8_YEAST - Uncharacterized protein YFR018C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFR018C ...
 5.0E-85 [1..363] [1..363]
gi|12856921 - gi|12856921|dbj|BAB30831.1| unnamed protein product [Mus musculus]
 3.0E-84 [10..358] [8..360]
QPCT - glutaminyl-peptide cyclotransferase
 9.0E-81 [10..358] [8..359]
QPCT_GLOBL - Glutaminyl-peptide cyclotransferase OS=Gloydius blomhoffii GN=QPCT PE=2 SV=1
 2.0E-76 [29..359] [40..366]
QPCT_BOVIN - Glutaminyl-peptide cyclotransferase OS=Bos taurus GN=QPCT PE=1 SV=1
 8.0E-75 [9..358] [7..359]
QPCT_BOTJA - Glutaminyl-peptide cyclotransferase OS=Bothrops jararaca GN=QPCT PE=2 SV=1
 8.0E-73 [12..359] [16..366]
CE17979 - guanylate cyclase status:Confirmed UniProt:O17912 protein_id:CAB08740.1
 1.0E-62 [12..358] [3..337]

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Predicted Domain #1
Region A:
Residues: [1-363] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMKYVLPLR LIGLAYLLVL FQVHRVTGWE LSYEQYHAAH LNEAINPDSG WNKSTKNLLL  60
   61 PFNRTRVPGS EGSREIQRFI IEHFNNTLAG EWAVETQAFE ENGYRFNNLV MTLQNNASEY 120
  121 LVLAAHYDTK IAPTGMVGAI DSAASCAALL YTAQFLTHIA CHERTKEYND LESNTVVSNS 180
  181 TLGVKIVFFD GEEAIEEWGP EDSIYGARRL AAQWLADGTM TRIRLLFLLD LLGSGEEEPL 240
  241 VPSYYAETHQ EYQLLNRIED DLLFRRGDEI NGESALAAEV ARQRKHLDPT DYRFLGLGHS 300
  301 VIGDDHTPFL AAGVPVLHAI PLPFPSTWHT VDDDFRHLDA AETRHWALLV CEFVVQSLRS 360
  361 RNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 1amp__
Description: Aminopeptidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.33010352069253 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.96046345079997 bayes_pls_golite062009
hydrolase activity 2.61327242243519 bayes_pls_golite062009
exopeptidase activity 1.70361627875478 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
metallopeptidase activity 1.34087538226325 bayes_pls_golite062009
carboxypeptidase activity 0.891655769761122 bayes_pls_golite062009
metalloexopeptidase activity 0.619120257877893 bayes_pls_golite062009
metallocarboxypeptidase activity 0.180859448845431 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle