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View Structure Prediction Details

Protein: NIC96
Organism: Saccharomyces cerevisiae
Length: 839 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NIC96.

Description E-value Query
Range
Subject
Range
gi|395232 - gi|395232|emb|CAA51427.1| NIC96 [Saccharomyces cerevisiae]
0.0 [1..839] [1..838]
gi|18606331 - gi|18606331|gb|AAH23140.1| Nucleoporin 93 [Mus musculus]
0.0 [24..839] [8..818]
gi|12718244 - gi|12718244|emb|CAC28552.1| related to nucleoporin-interacting protein NIC96 [Neurospora crassa]
0.0 [25..838] [226..1103]
gi|148230897, gi... - gi|1490628|gb|AAB49669.1| An4a, gi|148230897|ref|NP_001080591.1| dead eye-like [Xenopus laevis]
0.0 [24..839] [8..819]
gi|220943684 - gi|220943684|gb|ACL84385.1| CG11092-PA [synthetic construct]
CG11092-PA - This gene is referred to in FlyBase by the symbol Dmel\CG11092 (CG11092, FBgn0027537). It is a prote...
0.0 [16..839] [8..822]
mug87 - nucleoporin Nic96 homolog
MUG87_SCHPO - Meiotically up-regulated gene 87 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=m...
0.0 [18..839] [22..850]
NP93A_ARATH - Nuclear pore complex protein NUP93A OS=Arabidopsis thaliana GN=NUP93A PE=1 SV=2
0.0 [24..785] [12..823]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLETLRGNKL HSGTSKGANK KLNELLESSD NLPSASSELG SIQVSINELR RRVFQLRSKN  60
   61 KASKDYTKAH YLLANSGLSF EDVDAFIKDL QTNQFLEPNP PKIIESEELE FYIRTKKEEN 120
  121 ILMSIEQLLN GATKDFDNFI NHNLNLDWAQ HKNE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [677-696]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDDNSETNPV LLARRMASIY 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [155-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMKNFGILIQ DKKTVDHKKS ISSLDPKLPS WGNKGNNILN SNESRLNVNE NNILREKFEN  60
   61 YARIVFQFNN SRQANGNFDI ANEFISILSS ANGTRNAQLL ESWKILESMK SKDINIVEVG 120
  121 KQYLEQQFLQ YTDNLYKKNM NEGLATNVNK IKSFIDTKLK KADKSWKISN LTVINGVPIW 180
  181 ALIFYLLRAG LIKEALQVLV ENKANIKK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [482-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLLSGLYGLA IDYTYTFSEM DAVHLAIGLA SLKLFKIDSS TRLTKKPKRD IRFANILANY  60
   61 TKSFRYSDPR VAVEYLVLIT LNEGPTDVEL CHEALRELVL ETKEFTVLLG KIGRDGARIP 120
  121 GVIEERQPLL HVRDEKEFLH TITEQAARRA DEDGRIYDSI LLYQLAEEYD IVITLVNSLL 180
  181 SDTLSASDLD QPLVG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [697-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDNAGISRQI HVKNKEICML LLNISSIREL YFN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [363-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEQSFLTYFK AYASSKDHGL PVEYSTKLHT EYNQHIKSSL DGDPYRLAVY KLIGRCDLSR  60
   61 KNIPAVTLSI EDWLWMHLML IKEKDAENDP VYERYSLEDF QNIIISYGPS RFSNYYLQT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [730-839]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQWQETLSQM ELLDLLPFSD ELSARKKAQD FSNLDDNIVK NIPNLLIITL SCISNMIHIL  60
   61 NESKYQSSTK GQQIDSLKNV ARQCMIYAGM IQYRMPRETY STLINIDVSL 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.46
Match: 1b8fA
Description: Histidine ammonia-lyase (HAL)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle