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View Structure Prediction Details

Protein: FET5
Organism: Saccharomyces cerevisiae
Length: 622 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FET5.

Description E-value Query
Range
Subject
Range
FET5_YEAST - Iron transport multicopper oxidase FET5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
FET5 - Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron tra...
0.0 [1..622] [1..622]
FET3_CANAX - Iron transport multicopper oxidase FET3 OS=Candida albicans GN=FET3 PE=3 SV=1
0.0 [4..608] [7..593]
gi|7798835 - gi|7798835|emb|CAB90817.1| ferro-O2-oxidoreductase [Arxula adeninivorans]
0.0 [2..604] [1..586]
FET3_CANGA - Iron transport multicopper oxidase FET3 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 /...
FET3_CANGA - Iron transport multicopper oxidase FET3 OS=Candida glabrata GN=FET3 PE=3 SV=1
0.0 [6..609] [5..598]
gi|13171071 - gi|13171071|emb|CAC33177.1| Fet3 protein [Pichia pastoris]
0.0 [20..608] [2..576]
FIO1_SCHPO - Iron transport multicopper oxidase fio1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fi...
fio1 - iron transport multicopper oxidase Fio1
0.0 [3..615] [7..600]
gi|2264400 - gi|2264400|gb|AAB63445.1| phenoloxidase [basidiomycete CECT 20197]
0.0 [2..542] [10..523]
gi|16041065 - gi|16041065|dbj|BAB69775.1| laccase [Pycnoporus coccineus]
0.0 [3..542] [7..517]
gi|10179427, gi|... - gi|6466835|gb|AAF13052.1|AF170093_1 laccase [Pycnoporus cinnabarinus], gi|10179427|gb|AAG13724.1|AF1...
0.0 [3..542] [7..517]

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Predicted Domain #1
Region A:
Residues: [1-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFYSFVWSV LAASVALAKT HKLNYTASWV TANPDGLHEK RMIGFNGEWP LPDIHVEKGD  60
   61 RVELYLTNGF QDNTATSLHF HGLFQNTSLG NQLQMDGPSM VTQCPIVPGQ TYLYNFTVPE 120
  121 QVGTFWYHAH MGAQYGDGMR GAFIIHDPEE PFEYDHERVI TLSDHYHENY KTVTKEFLSR 180
  181 YNPTGAEPIP QNILFNNTMN VTLDFTPGET YLFRFLNVGL FVSQYIILED HEMSIVEVDG 240
  241 VYVKPNFTDS IYLSAGQRMS VLIKAKDKMP TRNYAMMQIM DETMLDVVPP ELQLNQTIQM 300
  301 RYGHSLPEAR ALNIEDCDLD RATND

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [525-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NENYLDICKA ADIPVVGNAA GHSNDWFDLK GLPRQPEPLP K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 599.9897
Match: 1kyaA_
Description: Laccase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [326-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYLEPLIERD LLAHYDHQIV MDVRMVNLGD GVKYAFFNNI TYVTPKVPTL TTLLTSGKLA  60
   61 SDPRIYGDNI NAQLLKHNDI IEVVLNNYDS GRHPFHLHGH NFQIVQKSPG FHVDEAYDES 120
  121 EQDEMTVPYN ESAPLQPFPE RPMVRDTVVL EPSGHVVLRF RADNPGVWYF HCHVDWHLQQ 180
  181 GLASVFIEAP VLLQEREKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 599.9897
Match: 1kyaA_
Description: Laccase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [566-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFTTEGYLAL IISTIIGVWG LYSIAQYGIG EVIPNDEKVY HTLREILAEN EIEVSRG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.512 d.58.17 Metal-binding domain
View Download 0.592 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.542 d.48.1 RecA protein, C-terminal domain
View Download 0.461 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.635 a.144.2 Ribosomal protein L20
View Download 0.456 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.448 d.52.1 Alpha-lytic protease prodomain
View Download 0.443 a.4.1 Homeodomain-like
View Download 0.440 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.421 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.386 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.343 a.28.1 ACP-like
View Download 0.342 a.140.1 LEM domain
View Download 0.331 a.4.1 Homeodomain-like
View Download 0.321 a.65.1 Annexin
View Download 0.319 d.58.49 YajQ-like
View Download 0.312 a.118.11 Cytochrome c oxidase subunit E
View Download 0.311 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.308 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.296 a.77.1 DEATH domain
View Download 0.292 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.291 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.290 d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.288 d.58.17 Metal-binding domain
View Download 0.286 a.159.2 FF domain
View Download 0.284 d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.283 a.49.1 C-terminal domain of B transposition protein
View Download 0.279 a.4.5 "Winged helix" DNA-binding domain
View Download 0.273 d.186.1 Head-to-tail joining protein W, gpW
View Download 0.263 a.4.5 "Winged helix" DNA-binding domain
View Download 0.262 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.261 d.10.1 DNA-binding domain
View Download 0.256 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.253 g.34.1 HIV-1 VPU cytoplasmic domain
View Download 0.248 a.4.5 "Winged helix" DNA-binding domain
View Download 0.240 d.64.1 eIF1-like
View Download 0.238 d.45.1 ClpS-like
View Download 0.237 d.58.17 Metal-binding domain
View Download 0.234 d.120.1 Cytochrome b5
View Download 0.234 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.232 d.58.8 Viral DNA-binding domain
View Download 0.232 d.58.17 Metal-binding domain
View Download 0.229 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.229 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.227 a.60.2 RuvA domain 2-like
View Download 0.216 a.4.1 Homeodomain-like
View Download 0.216 d.58.48 MTH1187-like
View Download 0.211 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.205 d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.204 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.203 d.68.7 R3H domain
View Download 0.201 d.58.12 eEF-1beta-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle