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View Structure Prediction Details

Protein: PAB1
Organism: Saccharomyces cerevisiae
Length: 577 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAB1.

Description E-value Query
Range
Subject
Range
gi|172092 - gi|172092|gb|AAA34838.1| polyadenylate-binding protein
0.0 [1..577] [1..577]
gi|126540996, gi... - gi|22507391|ref|NP_683717.1| poly(A) binding protein, cytoplasmic 4 isoform 2 [Mus musculus], gi|163...
0.0 [29..573] [2..604]
gi|19526272 - gi|19526272|gb|AAL89666.1|AF411956_7 polyA-binding protein [Takifugu rubripes]
0.0 [32..572] [5..607]
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1
gi|109087089 - gi|109087089|ref|XP_001098239.1| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca...
gi|123993665, gi... - gi|168278070|dbj|BAG11013.1| polyadenylate-binding protein 1 [synthetic construct], gi|123999981|gb|...
gi|194036975 - gi|194036975|ref|XP_001927782.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind...
PABPC1 - poly(A) binding protein, cytoplasmic 1
gi|73974130, gi|... - gi|73974178|ref|XP_857695.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
0.0 [29..573] [2..624]
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1
0.0 [29..573] [2..624]
gi|2665654 - gi|2665654|gb|AAB88449.1| polyadenylate binding protein [Petromyzon marinus]
0.0 [29..566] [2..616]
gi|7528270 - gi|7528270|gb|AAF63202.1|AF240679_1 poly(A)-binding protein [Cucumis sativus]
0.0 [16..576] [7..637]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADITDKTAE QLENLNIQDD QKQAATGSES QSVENSSASL YVGDLEPSVS EAHLYDIFSP  60
   61 IGSVSSIRVC RDAITKTSLG YAYVNFNDHE AGRKAIEQLN YTPIKGRLCR IMWSQR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 653.927757
Match: 1cvjA_
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.92126426323641 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [117-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPSLRKKGSG NIFIKNLHPD IDNKALYDTF SVFGDILSSK IATDENGKSK GFGFVHFEEE  60
   61 GAAKEAIDAL NGMLLNGQEI YVAPHLSRKE RDSQLEETK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 653.927757
Match: 1cvjA_
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [216-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHYTNLYVKN INSETTDEQF QELFAKFGPI VSASLEKDAD GKLKGFGFVN YEKHEDAVKA  60
   61 VEALNDSELN GEKLYVGRAQ KKNERMHVLK KQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.31133
Match: 1l3kA_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [308-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YEAYRLEKMA KYQGVNLFVK NLDDSVDDEK LEEEFAPYGT ITSAKVMRTE NGKSKGFGFV  60
   61 CFSTPEEATK AITEKNQQIV AGKPLYVAIA QRKDVRRSQL AQQIQARNQM RYQQATAAAA 120
  121 AAAAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.31133
Match: 1l3kA_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [433-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGQFMPPMF YGVMPPRGVP FNGPNPQQMN PMGGMPKNGM PPQFRNGPVY GVP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [486-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQGGFPRNAN DNNQFYQQKQ RQALGEQLYK KVSAKTSNEE AAGKITGMIL DLPPQEVFPL  60
   61 LESDELFEQH YKEASAAYES FKKEQEQQTE QA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 390.67837
Match: 1ifwA_
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle