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View Structure Prediction Details

Protein: DDI1
Organism: Saccharomyces cerevisiae
Length: 428 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DDI1.

Description E-value Query
Range
Subject
Range
gi|37532712, gi|... - gi|37532712|ref|NP_920658.1| putative retroelement [Oryza sativa (japonica cultivar-group)], gi|3143...
1.0E-94 [7..427] [472..882]
gi|18657020 - gi|18657020|gb|AAL78107.1|AC093568_17 Putative polyprotein [Oryza sativa]
gi|37531762, gi|... - gi|37531762|ref|NP_920183.1| putative polyprotein [Oryza sativa (japonica cultivar-group)], gi|31430...
2.0E-91 [7..427] [514..924]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLTISNELT GEIYGPIEVS EDMALTDLIA LLQADCGFDK TKHDLYYNMD ILDSNRTQSL  60
   61 KELGLKTDDL LLIRGKISNS IQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.39794
Match: 1aarA_
Description: Ubiquitin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.55392638191535 bayes_pls_golite062009
protein binding 1.54942742559883 bayes_pls_golite062009
small conjugating protein ligase activity 1.28693841442604 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.670372579002346 bayes_pls_golite062009
hydrolase activity 0.385840034768257 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [83-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDAATLSDEA FIEQFRQELL NNQMLRSQLI LQIPGLNDLV NDPLLFRERL GPLILQRRYG  60
   61 GYNTAMNPF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.849 0.263 SNARE binding a.77.1 DEATH domain

Predicted Domain #3
Region A:
Residues: [152-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIPQDEYTRL MANPDDPDNK KRIAELLDQQ AIDEQLRNAI EYTPEMFTQV PMLYINIEIN  60
   61 NYPVKAFVDT GAQTTIMSTR LAKKTGLSRM IDKRFIGEAR GVGTGKIIGR IHQAQVKIET 120
  121 QYIPCSFTVL DTDIDVLIGL DMLKRHLACV DLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 2aidA_
Description: Human immunodeficiency virus type 1 protease
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [305-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENVLRIAEVE TSFLSEAEIP KSFQEGLPAP TSVTTSSDKP LTPTKTSSTL PPQPGAVPAL  60
   61 APRTGMGPTP TGRSTAGATT ATG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 1rvnA_
Description: No description for 1rvnA_ was found.

Predicted Domain #5
Region A:
Residues: [388-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTFPEQTIKQ LMDLGFPRDA VVKALKQTNG NAEFAASLLF Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 1dv0A_
Description: DNA repair protein Hhr23a
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle