YRC Public Data Repository - Protein Structure Prediction

Protein:	NUP157
Organism:	Saccharomyces cerevisiae
Length:	1391 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP157.

Description	E-value	Query Range	Subject Range
NUP155 - nucleoporin 155kDa	0.0	[83..1347]	[15..1324]
gi\|2947312, gi\|2... - gi\|2981204\|gb\|AAC06247.1\| nucleoporin [Drosophila melanogaster], gi\|2947312\|gb\|AAC05386.1\| nucleopor...	0.0	[115..1336]	[50..1290]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[115..1336]	[50..1290]
NUP170 - Subunit of the nuclear pore complex (NPC), required for NPC localization of specific nucleoporins; i... NU170_YEAST - Nucleoporin NUP170 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP170 PE=1 SV=1	0.0	[15..1390]	[16..1495]
SPAC890.06 - nucleoporin Nup157 /170 NG06_SCHPO - Probable nucleoporin C890.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC890.06 PE...	0.0	[132..1373]	[56..1287]
NU155_RAT - Nuclear pore complex protein Nup155 OS=Rattus norvegicus GN=Nup155 PE=1 SV=1	0.0	[83..1347]	[14..1323]
gi\|10644743, gi\|... - gi\|74136117\|ref\|NP_001027921.1\| nucleoporin 153 [Takifugu rubripes], gi\|10644745\|gb\|AAG21383.1\| nucl...	0.0	[84..1347]	[11..1303]

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Predicted Domain #1

Region A:
Residues: [1-65]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSTPLKKRI DYDRETFTAS ASLGGNRLRN RPRDDQNNGK PNLSSRSFLS ERKTRKDVLN  60
   61 KYGEA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [66-1391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNTIESELRD VTTHVKISGL TSSEPLQLAS EFVQDLSFRD RNTPILDNPD YYSKGLDYNF  60
   61 SDEVGGLGAF TPFQRQQVTN IPDEVLSQVS NTEIKSDMGI FLELNYCWIT SDNKLILWNI 120
  121 NNSSEYHCID EIEHTILKVK LVKPSPNTFV SSVENLLIVA TLFDIYILTI SFNDRTHELN 180
  181 IFNTGLKVNV TGFNVSNIIS YERTGQIFFT GATDGVNVWE LQYNCSENLF NSKSNKICLT 240
  241 KSNLANLLPT KLIPSIPGGK LIQKVLEGDA GTEEETISQL EVDQSRGVLH TLSTKSIVRS 300
  301 YLITSNGLVG PVLIDAAHIR RGMNALGVKN SPLLSNRAFK IAKIVSISMC ENNDLFLAVI 360
  361 TTTGVRLYFK GSISRRSIGS LKLDSVKFPP TSISSSLEQN KSFIIGHHPL NTHDTGPLST 420
  421 QKASSTYINT TCASTIISPG IYFTCVRKRA NSGELSKGIT NKALLENKEE HKLYVSAPDY 480
  481 GILKNYGKYV ENTALLDTTD EIKEIVPLTR SFNYTSTPQG YANVFASQYS AEPLKVAVLT 540
  541 SNALEIYCYR TPDEVFESLI ENPLPFIHSY GLSEACSTAL YLACKFNKSE HIKSSALAFF 600
  601 SAGIPGVVEI KPKSSRESGS VPPISQNLFD KSGECDGIVL SPRFYGSALL ITRLFSQIWE 660
  661 ERVFVFKRAS KTEKMDAFGI SITRPQVEYY LSSISVLADF FNIHRPSFVS FVPPKGSNAI 720
  721 TASDAESIAM NALILLINSI KDALSLINVF YEDIDAFKSL LNTLMGAGGV YDSKTREYFF 780
  781 DLKFHDLFTP NAKTKQLIKE ILIEVVNANI ASGTSADYIV NVLKERFGSF CHSADILCYR 840
  841 AGEHLEAAQK FEMIDSKISR NHLDTAIDLY ERCAENIELC ELRRVVDIMV KLNYQPKTVG 900
  901 FLLRFADKID KGNQAQEYVS RGCNTADPRK VFYDKRINVY TLIFEIVKSV DDYTSIEQSP 960
  961 SIANISIFSP ASSLKKRVYS VIMNSNNRFF HYCFYDWLVA NKRQDYLLRL DSQFVLPYLK1020
 1021 ERAEKSLEIS NLLWFYLFKE EHFLEAADVL YALASSDFDL KLSERIECLA RANGLCDSST1080
 1081 SFDQKPALVQ LSENIHELFD IASIQDDLLN LVRNETRIDE DYRKQLTLKL NGRVLPLSDL1140
 1141 FNDCADPLDY YEIKLRIFKV SQFKDEKVIQ GEWNRLLDSM KNAPSPDVGS VGQESFLSSI1200
 1201 SNTLIRIGKT TRDTDVVFPV HFLMNKILES FIDKSSAADG SVCSMFLLAG VSHLKLYYIL1260
 1261 SRIIENSEGN VELAKKEMVW LIKDWYQSDS DLRGSIAPEQ IKKLEKYDPN TDPVQDYVKD1320
 1321 RHHGLK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	1000.0
Match:	PF03177
Description:	Non-repetitive/WGA-negative nucleoporin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [258-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNVSNIISYE RTGQIFFTGA TDGVNVWELQ YNCSENLFNS KSNKICLTKS NLANLLPTKL  60
   61 IPSIPGGKLI QKVL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [332-437]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGDAGTEEET ISQLEVDQSR GVLHTLSTKS IVRSYLITSN GLVGPVLIDA AHIRRGMNAL  60
   61 GVKNSPLLSN RAFKIAKIVS ISMCENNDLF LAVITTTGVR LYFKGS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [438-672]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISRRSIGSLK LDSVKFPPTS ISSSLEQNKS FIIGHHPLNT HDTGPLSTQK ASSTYINTTC  60
   61 ASTIISPGIY FTCVRKRANS GELSKGITNK ALLENKEEHK LYVSAPDYGI LKNYGKYVEN 120
  121 TALLDTTDEI KEIVPLTRSF NYTSTPQGYA NVFASQYSAE PLKVAVLTSN ALEIYCYRTP 180
  181 DEVFESLIEN PLPFIHSYGL SEACSTALYL ACKFNKSEHI KSSALAFFSA GIPGV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [673-856]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEIKPKSSRE SGSVPPISQN LFDKSGECDG IVLSPRFYGS ALLITRLFSQ IWEERVFVFK  60
   61 RASKTEKMDA FGISITRPQV EYYLSSISVL ADFFNIHRPS FVSFVPPKGS NAITASDAES 120
  121 IAMNALILLI NSIKDALSLI NVFYEDIDAF KSLLNTLMGA GGVYDSKTRE YFFDLKFHDL 180
  181 FTPN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7

Region A:
Residues: [857-915]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKTKQLIKEI LIEVVNANIA SGTSADYIVN VLKERFGSFC HSADILCYRA GEHLEAAQK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8

Region A:
Residues: [916-1059]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEMIDSKISR NHLDTAIDLY ERCAENIELC ELRRVVDIMV KLNYQPKTVG FLLRFADKID  60
   61 KGNQAQEYVS RGCNTADPRK VFYDKRINVY TLIFEIVKSV DDYTSIEQSP SIANISIFSP 120
  121 ASSLKKRVYS VIMNSNNRFF HYCF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9

Region A:
Residues: [1060-1247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDWLVANKRQ DYLLRLDSQF VLPYLKERAE KSLEISNLLW FYLFKEEHFL EAADVLYALA  60
   61 SSDFDLKLSE RIECLARANG LCDSSTSFDQ KPALVQLSEN IHELFDIASI QDDLLNLVRN 120
  121 ETRIDEDYRK QLTLKLNGRV LPLSDLFNDC ADPLDYYEIK LRIFKVSQFK DEKVIQGEWN 180
  181 RLLDSMKN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10

Region A:
Residues: [1248-1391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APSPDVGSVG QESFLSSISN TLIRIGKTTR DTDVVFPVHF LMNKILESFI DKSSAADGSV  60
   61 CSMFLLAGVS HLKLYYILSR IIENSEGNVE LAKKEMVWLI KDWYQSDSDL RGSIAPEQIK 120
  121 KLEKYDPNTD PVQDYVKDRH HGLK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits