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View Structure Prediction Details

Protein: UTP7
Organism: Saccharomyces cerevisiae
Length: 554 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP7.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [3..458] [984..1440]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [4..425] [836..1257]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID EQYKKAVSSA  60
   61 AATDYLLPES NGYLEPENEL EKTFKVQQSE IK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.648 a.1.1 Globin-like
View Download 0.508 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.485 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.515 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.470 a.4.1 Homeodomain-like
View Download 0.460 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.456 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.456 a.61.1 Retroviral matrix proteins
View Download 0.447 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.440 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.407 d.8.1 Urease, gamma-subunit
View Download 0.406 f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.403 a.24.17 Group V grass pollen allergen
View Download 0.395 a.118.1 ARM repeat
View Download 0.371 a.4.5 "Winged helix" DNA-binding domain
View Download 0.360 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.358 a.4.12 TrpR-like
View Download 0.341 a.7.7 BAG domain
View Download 0.340 a.85.1 Hemocyanin, N-terminal domain
View Download 0.329 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.326 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.313 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.312 a.47.2 t-snare proteins
View Download 0.308 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.305 a.40.1 Calponin-homology domain, CH-domain
View Download 0.304 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.288 a.1.1 Globin-like
View Download 0.281 a.112.1 Description not found.
View Download 0.277 f.17.1 F1F0 ATP synthase subunit C
View Download 0.269 a.64.1 Saposin
View Download 0.246 a.2.7 tRNA-binding arm
View Download 0.243 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.240 a.2.7 tRNA-binding arm
View Download 0.234 a.105.1 FIS-like
View Download 0.233 a.51.1 Cytochrome c oxidase subunit h
View Download 0.227 a.71.2 Helical domain of Sec23/24
View Download 0.225 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.225 a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.224 a.26.1 4-helical cytokines
View Download 0.223 a.5.6 Hypothetical protein MTH1615
View Download 0.220 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.213 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.209 a.8.1 Bacterial immunoglobulin/albumin-binding domains

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 1.83286470399158 bayes_pls_golite062009
transcription regulator activity 1.25687092973217 bayes_pls_golite062009
nucleic acid binding 1.20712373307552 bayes_pls_golite062009
structural molecule activity 1.20572493724069 bayes_pls_golite062009
protein binding 0.987581964031738 bayes_pls_golite062009
DNA binding 0.711274653406079 bayes_pls_golite062009
cytoskeletal protein binding 0.523052412917759 bayes_pls_golite062009
transcription factor activity 0.243992994917491 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009
ligase activity 0.00971558442368137 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [93-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVDVSTANK ALDLSLKEFG PYHIKYAKNG THLLITGRKG HVASMDWRKG QLRAELFLNE  60
   61 TCHSATYLQN EQYFAVAQKK YTFIYDHEGT ELHRLKQHIE ARHLDFLPYH YLLVTAGETG 120
  121 WLKYHDVSTG QLVSELRTKA GPTMAMAQNP WNAVMHLGHS NGTVSLWSPS MPEPLVKLLS 180
  181 ARGPVNSIAI DRSGYYMATT GADRSMKIWD IRNFKQLHSV ESLPTPGTNV SISDTGLLAL 240
  241 SRGPHVTLWK DALKLSGDSK PCFGSMGGNP HRNTPYMSHL FAGNKVENLG FVPFEDLLGV 300
  301 GHQTGITNLI VPGAGEANYD ALELNPFETK KQRQEQEVRT LLNKLPADTI TLDPNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.522879
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [449-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGSVDKRSST IRLNAKDLAQ TTMDANNKAK TNSDIPDVKP DVKGKNSGLR SFLRKKTQNV  60
   61 IDERKLRVQK QLDKEKNIRK RNHQIKQGLI SEDHKDVIEE ALSRFG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.340 a.29.2 Bromodomain
View Download 0.293 a.7.8 GAT domain
View Download 0.216 a.24.4 Hemerythrin
View Download 0.219 i.11.1 Computational models partly based on NMR data
View Download 0.216 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.208 a.4.5 "Winged helix" DNA-binding domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle