YRC Public Data Repository - Protein Structure Prediction

Protein:	ARG5,6
Organism:	Saccharomyces cerevisiae
Length:	863 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARG5,6.

Description	E-value	Query Range	Subject Range
gi\|151944784 - gi\|151944784\|gb\|EDN63043.1\| N-acetyl-gamma-glutamyl-phosphate reductase [Saccharomyces cerevisiae YJ... ARG56_YEAST - Protein ARG5,6, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG5,6 PE=... gi\|190405632 - gi\|190405632\|gb\|EDV08899.1\| N-acetyl-gamma-glutamyl-phosphate reductase [Saccharomyces cerevisiae RM... gi\|207345942 - gi\|207345942\|gb\|EDZ72596.1\| YER069Wp-like protein [Saccharomyces cerevisiae AWRI1631] ARG5,6 - Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-gl...	0.0	[1..863]	[1..863]
AR56_NEUCR, ARG5... - Protein arg-6, mitochondrial OS=Neurospora crassa GN=arg-6 PE=1 SV=1, (P54898) Arg-6 protein, mitoch... ARG56_NEUCR - Protein arg-6, mitochondrial OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM...	0.0	[30..858]	[9..871]
ARG56_CANAX - Protein ARG5,6, mitochondrial OS=Candida albicans GN=ARG5,6 PE=3 SV=1	0.0	[64..861]	[50..855]
arg11 - N-acetyl-gamma-glutamyl-phosphate reductase /acetylglutamate kinase ARG56_SCHPO - Protein arg11, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=arg11 PE=3 SV...	0.0	[68..855]	[62..882]
gi\|4906 - gi\|4906\|emb\|CAA45132.1\| N-acetyl-gamma-glutamyl-phosphate reductase; acetylglutamate kinase [Schizos...	0.0	[68..855]	[62..882]
gi\|9105937, gi\|1... - gi\|9105937\|gb\|AAF83811.1\|AE003938_2 acetylglutamate kinase [Xylella fastidiosa 9a5c], gi\|15837603\|re... gi\|11360469 - gi\|11360469\|pir\|\|H82734 acetylglutamate kinase XF1001 [imported] - Xylella fastidiosa (strain 9a5c)	0.0	[67..496]	[7..428]
gi\|19699208, gi\|... - gi\|19699208\|gb\|AAL90970.1\| At2g19940/F6F22.3 [Arabidopsis thaliana], gi\|16604368\|gb\|AAL24190.1\| At2g...	1.0E-99	[507..862]	[29..401]
gi\|1591740, gi\|1... - gi\|1591740\|gb\|AAB99099.1\| N-acetyl-gamma-glutamyl-phosphate reductase (argC) [Methanocaldococcus jan... gi\|2129135 - gi\|2129135\|pir\|\|G64436 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) - Methanococcus jan...	3.0E-96	[523..862]	[17..375]
ARGC_THEMA - N-acetyl-gamma-glutamyl-phosphate reductase OS=Thermotoga maritima GN=argC PE=1 SV=1 ARGC_THEMA - N-acetyl-gamma-glutamyl-phosphate reductase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3...	5.0E-96	[541..862]	[2..339]

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Predicted Domain #1

Region A:
Residues: [1-96]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSASLLVST KRLNASKFQK FVSSLNKSTI AGFASVPLRA PPSVAFTRKK VGYSKRYVSS  60
   61 TNGFSATRST VIQLLNNIST KREVEQYLKY FTSVSQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [97-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQFAVIKVGG AIISDNLHEL ASCLAFLYHV GLYPIVLHGT GPQVNGRLEA QGIEPDYIDG  60
   61 IRITDEHTMA VVRKCFLEQN LKLVTALEQL GVRARPITSG VFTADYLDKD KYKLVGNIKS 120
  121 VTKEPIEASI KAGALPILTS LAETASGQML NVNADVAAGE LARVFEPLKI VYLNEKGGII 180
  181 NGSTGEKISM INLDEEYDDL MKQSWVKYGT KLKIREIKEL LDYLPRSSSV AIINVQDLQK 240
  241 ELFTDSGAGT MIRRGYKLVK RSSIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.512579
Match:	1gs5A_
Description:	N-acetyl-l-glutamate kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [362-528]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFPSADALRK ALQRDAGISS GKESVASYLR YLENSDFVSY ADEPLEAVAI VKKDTNVPTL  60
   61 DKFVCSDAAW LNNVTDNVFN VLRRDFPALQ WVVSENDANI AWHFDKSQGS YLKGGKVLFW 120
  121 YGIDDINTIS ELVENFVKSC DTASTLNSSA SSGVFANKKS ARSYSTR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [529-673]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STPRPEGVNT NPGRVALIGA RGYTGKNLVS LINGHPYLEV AHVSSRELKG QKLQDYTKSE  60
   61 IIYESLQIQD IRKLEEQNAV DFWVMALPNK VCEPFVETIQ SVHGKSKIID LSADHRFVSE 120
  121 SDWAYGLPEL NDRAKIANAA KIANP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.522879
Match:	1gpdG_
Description:	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [674-863]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCYATGSQLT ISPLTKYING LPTVFGVSGY SGAGTKPSPK NDPKFLNNNL IPYALSDHIH  60
   61 EREISARIGH NVAFMPHVGQ WFQGISLTVS IPIKKGSLSI DEIRKLYRNF YEDEKLVHVI 120
  121 DDIPLVKDIE GTHGVVIGGF KLNDAEDRVV VCATIDNLLK GAATQCLQNI NLAMGYGEYA 180
  181 GIPENKIIGV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.522879
Match:	1gpdG_
Description:	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits