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View Structure Prediction Details

Protein: TPA1
Organism: Saccharomyces cerevisiae
Length: 644 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPA1.

Description E-value Query
Range
Subject
Range
TPA1 - Poly(rA)-binding protein involved in translation termination efficiency, mRNA poly(A) tail length an...
TPA1_YEAST - Prolyl 3,4-dihydroxylase TPA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPA1 PE=1 ...
0.0 [1..644] [1..644]
OFD1_SCHPO - Prolyl 3,4-dihydroxylase ofd1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ofd1 PE=1 SV...
ofd1 - 2-oxoglutarate and Fe(II) dioxygenase domain containing protein 1
0.0 [22..631] [5..511]
gi|11596258 - gi|11596258|gb|AAG38547.1|AF309805_12 Yer049wp-like protein [Pneumocystis carinii f. sp. carinii]
0.0 [26..418] [5..368]
gi|10433458 - gi|10433458|dbj|BAB13967.1| unnamed protein product [Homo sapiens]
7.0E-85 [9..341] [17..360]
gi|14547239 - gi|14547239|emb|CAC42515.1| EGLN1 protein [Mus musculus]
4.0E-55 [35..254] [137..343]
CE01785 - status:Partially_confirmed UniProt:Q09973 protein_id:AAB93451.1
1.0E-52 [1..262] [1..254]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRKTAEVKG EKERNSKQIS LEEDKIKGMF NPKIWDKTFQ DGLKKEIEDS QPYNWGTIHE  60
   61 LVNDDLLRAV RKEIETEIHF TKKETDIYRV NQSGDLANLS GLDWDDLSRL PNLFKLRQIL 120
  121 YSKQYRDFFG YVTKAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [137-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLSGSKTDMS INTYTKGCHL LTHDDVIGSR RISFILYLPD PDRKWKSHYG GGLRLFPSIL  60
   61 PNVPHSDPSA KLVPQFNQIA FFKVLPGFSF HDVEEVKVDK HRLSIQGWYH IPQVGEEGYI 120
  121 PGEEEAWVRN NTSTLAQIES NVLEDFEFPK DERNILSFHE VKHFEKMLKG 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 10.455932
Match: PF03171
Description: 2OG-Fe(II) oxygenase superfamily

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.657 N/A N/A a.112.1 Description not found.
View Download 0.587 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.541 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.531 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.504 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone

Predicted Domain #3
Region A:
Residues: [307-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAGAKTDNTP KESMTSVISD SVKLSEAEFT YLSQYISPEH LSSKGIEKLQ KQFVENSSLQ  60
   61 IESFLNDDKS ELLKKVIKQK ELEQECPYHS KDVKAPWKTA IPPHKARYLY IDGKEYRNFQ 120
  121 TEADILEALN NNDLPNFQFT KDAIKIISDA SGNSRENNFD AELALIDLAV FHKSTIFKKY 180
  181 LALLTSLCPV SEQILIRRFR PGMDFTLATK CRFNELLKSN PDIIDAVLEG TLCLTPSAGW 240
  241 ESGELGGYEL YMMDDDEDNK QYLKEDVEDA SVYRADDSGD SVLINDPPAW NTFNLVLRDE 300
  301 SVLEFVKYVS WSAKSSRWDV KMKWDVKSCD EDGQEDEA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [408-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPHKARYLYI DGKEYRNFQT EADILEALNN NDLPNFQFTK DAIKIISDAS GNSRENNFDA  60
   61 ELALIDLAVF HKSTIFKKYL ALLTSLCPVS EQILIRRFRP GMDFTLATKC RFNELLKSNP 120
  121 DIIDAVLEGT LCLTPSAGWE SGELGGYELY MMDDDEDNKQ YLKEDVEDAS VYRADDSGDS 180
  181 VLINDPPAWN TFNLVLRDES VLEFVKYVSW SAKSSRWDVK MKWDVKSCDE DGQEDEA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle