YRC Public Data Repository - Protein Structure Prediction

Protein:	SAP1
Organism:	Saccharomyces cerevisiae
Length:	897 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAP1.

Description	E-value	Query Range	Subject Range
SAP1_YEAST - Protein SAP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAP1 PE=1 SV=1 SAP1 - Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hyb...	0.0	[1..897]	[1..897]
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...	0.0	[344..894]	[199..730]
gi\|18159541, gi\|... - gi\|18312110\|ref\|NP_558777.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	0.0	[331..891]	[180..713]
gi\|5106179, gi\|1... - gi\|5106179\|dbj\|BAA81490.1\| 699aa long hypothetical transitional endoplasmic reticulum ATPase [Aeropy... gi\|7435761 - pir\|\|B72479 probable transitional endoplasmic reticulum ATPase APE2474 - Aeropyrum pernix (strain K1...	0.0	[316..890]	[136..681]
VAT_THEAC - VCP-like ATPase OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / ... VAT_THEAC - VCP-like ATPase OS=Thermoplasma acidophilum GN=vat PE=1 SV=1	0.0	[210..897]	[102..732]
gi\|15920392, gi\|... - gi\|15920392\|ref\|NP_376061.1\| hypothetical protein ST0209 [Sulfolobus tokodaii str. 7], gi\|15621174\|d...	0.0	[344..891]	[129..673]
gi\|14325192, gi\|... - gi\|14325192\|dbj\|BAB60117.1\| cell cycle control protein 48 [Thermoplasma volcanium GSS1], gi\|13541778...	0.0	[210..897]	[102..732]
gi\|13813572, gi\|... - gi\|15897351\|ref\|NP_341956.1\| AAA ATPase family protein [Sulfolobus solfataricus P2], gi\|13813572\|gb\|... gi\|25289959 - pir\|\|C90186 AAA family ATPase [imported] - Sulfolobus solfataricus	0.0	[256..895]	[142..766]
SAV_SULAC - Protein SAV OS=Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIM... SAV_SULAC - Protein SAV OS=Sulfolobus acidocaldarius GN=sav PE=3 SV=2	0.0	[320..895]	[202..778]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSQRSHHIL TRLTKIRRRP QQPLTDFTEL YSRIANETIY YLNLEEKKRY KEALQGWKAL  60
   61 TTDVLFKQTL IEHNYPNTQS YTKDEVSLQN GIRELYHKSV MHLKRVKKLV REEPAPRNDM 120
  121 PSSKTYTNHS SSFTRSTEPP PVFQMVPGRM MKTLRNR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [158-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NACGYKTAYS NPSLSSYGNS TSIKRGEDAE NIRVNFVPSK PLSNNASRQH KNPIEHNDPP  60
   61 LKKETELYSD KYISEPILID LTNDEDDHDV GILKGHNVFD EEESDGFEFD VSDYYDNFSE 120
  121 VDVEEEEEEK EERRRIKTLE AIQQQMSDLS VTSSTSSNKS VSSSEN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [324-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPGSCIQSLP TTAPALPSLP PPPLLNVDRA SSTGALKPHS LETSTTMDSS KIRNPQISKL  60
   61 MKNNHVPYLK GTKSTPTLIT K

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [405-526]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STPTFITRSK SNTKPIIKSN ASSPTSSLTV PNSVIQKPKT AAMAAKRVLN SKKVASNPAL  60
   61 NTTKKSHPIL KSKTAKVPNS SSKKTSSHPS RPVSNSKPYS HGASQNKKPS KNQTTSMSKT 120
  121 NR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	438.616428
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [527-601]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIPAQKKIGS PKIEDVGTED ATEHATSLNE QREEPEIDKK VLREILEDEI IDSLQGVDRQ  60
   61 AAKQIFAEIV VHGDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	438.616428
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [602-790]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHWDDIAGLE SAKYSLKEAV VYPFLRPDLF RGLREPVRGM LLFGPPGTGK TMLARAVATE  60
   61 SHSTFFSISA SSLTSKYLGE SEKLVRALFA IAKKLSPSII FVDEIDSIMG SRNNENENES 120
  121 SRRIKNEFLV QWSSLSSAAA GSNKSNTNNS DTNGDEDDTR VLVLAATNLP WSIDEAARRR 180
  181 FVRRQYIPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	438.616428
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [791-897]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEDQTRHVQF KKLLSHQKHT LTESDFDELV KITEGYSGSD ITSLAKDAAM GPLRDLGDKL  60
   61 LETEREMIRP IGLVDFKNSL VYIKPSVSQD GLVKYEKWAS QFGSSGS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	438.616428
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits