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View Structure Prediction Details

Protein: VPS52
Organism: Saccharomyces cerevisiae
Length: 641 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS52.

Description E-value Query
Range		 Subject
Range
gi|454893 - gi|454893|emb|CAA82878.1| Sac2 protein [Saccharomyces cerevisiae]
 0.0 [1..641] [1..641]
VPS52_RAT - Vacuolar protein sorting-associated protein 52 homolog OS=Rattus norvegicus GN=Vps52 PE=2 SV=2
 0.0 [10..606] [65..601]
gi|17826763 - gi|17826763|emb|CAD18902.1| suppressor of action mutation 2-like protein [Macaca mulatta]
 0.0 [10..606] [35..569]
gi|3811383 - gi|3811383|gb|AAC69899.1| Sacm21 [Mus musculus]
 0.0 [10..606] [65..599]
VP52A_ARATH - Vacuolar protein sorting-associated protein 52 A OS=Arabidopsis thaliana GN=VPS52 PE=1 SV=1
 0.0 [2..583] [38..563]
CG7371-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7371 (CG7371, FBgn0031710). It is a protein...
 0.0 [10..606] [13..546]

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Predicted Domain #1
Region A:
Residues: [1-122] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVLKEVLSL DQDKFDQLKE TSRDKTNETD DPFENYLKDC KFKAPSNKDQ SPFAKLKSLQ  60
   61 ETHSNNEAAI NIIIPQLIDY LTEFTNRLSN YTQDLDFIKK KSNELQSLLE YNSTKLAHIS 120
  121 PM

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [255-327] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CYTMKWYYRE YFSRYIRSLT ILQFQQIDSQ FALGNGLSTT SVSGFNNSPS LFFSNYLTTS  60
   61 ASNAFYNKLP VTD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.21
Match: 1h6oA
Description: TRF1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [123-254] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNDLMIPPEL IDDIIKGKIN ESWQDNITFI ADKEEIYNKY RSNNLDQDNK DAENSAMLAP  60
   61 KDFDKLCQLL DILKNVILER SKRLIISKIK TLRSHNPVPS QRIQNKLLKV QKIFPFIRDN 120
  121 NLSLALELRQ AY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.21
Match: 1h6oA
Description: TRF1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [328-641] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKIDKYFQIK KRLNILTQED NTVMVSQIAE NNTTKNYIEI GFKNLNLAIL DNCTVEYHFL  60
   61 KDFFAMNGDN FEEINGLLEQ IFQPTFDEAT TYTQQLIQYN YDIFGVLISI RVANQLQFES 120
  121 ERRGIPSMFD SFLNGQLIQL WPRFQQLVDF QCESLRKAAI TTNVAKYAGN SSTSNSSPLT 180
  181 SPHELTVQFG KFLSSFLTLA ITHKQSIDER SEPLYNSIIR LRNDFETVMT KCSKKTKSPE 240
  241 RFLATNYMYL YNNLQQLHLH LNINDSDAQN YNFDSAENVG TKVANDDDND SSVPLIIRET 300
  301 ENHFKTLVEA FTRN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.816 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle