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View Structure Prediction Details

Protein: TFC6
Organism: Saccharomyces cerevisiae
Length: 672 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFC6.

Description E-value Query
Range
Subject
Range
TFC6 - One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of ...
gi|151942334 - gi|151942334|gb|EDN60690.1| tau 91 subunit of transcription factor TFIIIC [Saccharomyces cerevisiae ...
TFC6_YEAST - Transcription factor tau 91 kDa subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
0.0 [1..672] [1..672]
sfc6 - transcription factor TFIIIC complex subunit Sfc6
SFC6_SCHPO - Transcription factor tau subunit sfc6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sfc6...
0.0 [274..672] [191..577]

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Predicted Domain #1
Region A:
Residues: [1-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVIPAKKRG RPRKSVVAEV PYDSLASPVS ENSGSKRPRR NASKKAVANF AQLVHAGRDD  60
   61 VINTTQVNNV DDTDDDDFVL NDEGDGEESD NVEIEFENEL ESTKNEVADL NSSGSGASVR 120
  121 PSGRRNTVQK LRLKKNSTKN MKSSSPGSSL GQKGRPIRLL KDLSSARDKI ERIYGLNKEK 180
  181 LLLLAKVKEG FETSVFDFPF KNIQPDSPYF VCLDPPCKKE SAYNKVIGDK NRTVYHEINK 240
  241 TEFENMIKLR TKRLKLLIGE VDAEVSTGDK IEFPVLANGK RRGFIYNVGG LVTDIAWLNI 300
  301 EENTDI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [307-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKDIQYLAVA VSQYMDEPLN EHLEMFDKEK HSSCIQIFKM NTSTLHCVKV QTIVHSFGEV  60
   61 WDLKWHEGCH APHLVGCLSF VSQEGTINFL EIIDNATDVH VFKMCEKPSL TLSLADSLIT 120
  121 TFDFLSPTTV VCGFKNGFVA EFDLTDPEVP SFYDQVHDSY ILSVSTAYSD FEDTVVSTVA 180
  181 VDGYFYIFNP KDIATTKTTV SRFRGSNLVP VVYCPQIYSY IYSDGASSLR AVPSRAAFAV 240
  241 HPLVSRETTI TAIGVSRLHP MVLAGSADGS LIITNAARRL LHGIKNSSAT QKSLRLWKWD 300
  301 YSIKDDKYRI DSSYEVYPLT VNDVSKAKID AHGINITCTK WNETSAGGKC YAFSNSAGLL 360
  361 TLEYLS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.02
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle