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View Structure Prediction Details

Protein: TFB1
Organism: Saccharomyces cerevisiae
Length: 642 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFB1.

Description E-value Query
Range
Subject
Range
gi|190404747 - gi|190404747|gb|EDV08014.1| RNA polymerase II transcription factor B subunit 1 [Saccharomyces cerevi...
TFB1_YEAST - RNA polymerase II transcription factor B subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...
gi|207346467 - gi|207346467|gb|EDZ72953.1| YDR311Wp-like protein [Saccharomyces cerevisiae AWRI1631]
TFB1 - Subunit of TFIIH and nucleotide excision repair factor 3 complexes, required for nucleotide excision...
gi|151942283 - gi|151942283|gb|EDN60639.1| transcription initiation factor TFIIH subunit [Saccharomyces cerevisiae ...
0.0 [1..642] [1..642]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [5..583] [9..579]
GTF2H1 - general transcription factor IIH, polypeptide 1, 62kDa
gi|168277836, gi... - gi|168277836|dbj|BAG10896.1| TFIIH basal transcription factor complex p62 subunit [synthetic constru...
0.0 [165..587] [96..498]
gi|12836734, gi|... - gi|31982313|ref|NP_032212.2| general transcription factor II H, polypeptide 1 [Mus musculus], gi|128...
0.0 [165..587] [96..497]
tfb1 - transcription factor TFIIH complex subunit Tfb1
TFB1_SCHPO - RNA polymerase II transcription factor B subunit 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2...
0.0 [76..572] [10..412]
gi|6850833, gi|1... - gi|6850833|emb|CAB71072.1| putative protein [Arabidopsis thaliana], gi|15233107|ref|NP_191701.1| tra...
1.0E-75 [164..444] [78..357]

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Predicted Domain #1
Region A:
Residues: [1-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHSGAAIFE KVSGIIAINE DVSPAELTWR STDGDKVHTV VLSTIDKLQA TPASSEKMML  60
   61 RLIGKVDESK KRKDNEGNEV VPKPQRHMFS FNNRTVMDNI KMTLQQIISR YKDADIYEEK 120
  121 RRREESAQHT ETPMSSSSVT AGTPTPHLDT PQLNNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
nucleic acid binding 1.85794418941003 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [157-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APLINTAKLD DSLSKEKLLT NLKLQQSLLK GNKVLMKVFQ ETVINAGLPP SEFWSTRIPL  60
   61 LRAFALSTSQ KVGPYNVLST IK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.60206
Match: PF03909
Description: BSD domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [239-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVASSENKVN VNLSREKILN IFENYPIVKK AYTDNVPKNF KEPEFWARFF SSKLFRKLRG  60
   61 EKIMQNDRGD VIIDRYLTLD QEFDRKDDDM LLHPVKKIID LDGNIQDDPV VRGN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 15.69897
Match: PF03909
Description: BSD domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [353-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPDFTMQPGV DINGNSDGTV DILKGMNRLS EKMIMALKNE YSRTNLQNKS NITNDEEDED  60
   61 NDERNELKID DLNESYKTNY AIIHLKRNAH EKTTDNDAKS SADSIKNADL KVSNQQMLQQ 120
  121 LSLVMDNLIN KLDLNQVVPN NEVSNKINKR VITAIKINAK QAKHNNVNSA LGSFVDNTSQ 180
  181 ANELEVKSTL PIDLLESCRM LHTTCCEFLK HFYIHFQSGE QKQASTVKKL YNHLKDCIEK 240
  241 LNELFQDVLN GDGESMSNTC TAYLKPVLNS ITLATHKYDE YFNEYNNNSN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [570-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGEQKQASTV KKLYNHLKDC IEKLNELFQD VLNGDGESMS NTCTAYLKPV LNSITLATHK  60
   61 YDEYFNEYNN NSN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle