YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: GTB1
Organism: Saccharomyces cerevisiae
Length: 702 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTB1.

Description E-value Query
Range
Subject
Range
gi|207346577 - gi|207346577|gb|EDZ73035.1| YDR221Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GLU2B_YEAST - Glucosidase 2 subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GTB1 PE=1 SV=...
gi|190404828 - gi|190404828|gb|EDV08095.1| hypothetical protein SCRG_00303 [Saccharomyces cerevisiae RM11-1a]
GTB1 - Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two gl...
gi|151942199 - gi|151942199|gb|EDN60555.1| glucosidase II beta subunit [Saccharomyces cerevisiae YJM789]
0.0 [1..702] [1..702]
gi|15488917, gi|... - gi|32880059|gb|AAP88860.1| protein kinase C substrate 80K-H [Homo sapiens], gi|15488917|gb|AAH13586....
2.0E-53 [444..682] [131..377]
GLU2B_BOVIN - Glucosidase 2 subunit beta OS=Bos taurus GN=PRKCSH PE=2 SV=1
6.0E-51 [444..683] [259..513]
ERLEC_MOUSE - Endoplasmic reticulum lectin 1 OS=Mus musculus GN=Erlec1 PE=1 SV=1
1.0E-47 [491..690] [63..247]

Back

Predicted Domain #1
Region A:
Residues: [1-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSMFSLFLL LIEQSPLVAS LQQSQRHIVG VPWEKQHLYD SNEPDLTKWH CLNHEDIVLD  60
   61 ISQINDGVCD CPDGSDEPGS AACVEDIFKS VAEGGGKVNK YFYCDNKGFI PRYIRKSEVA 120
  121 DGICDCCDCS DELLSGYELF DAGSNCSQLK NEFDIMASKE LSSYREGKEA LEELERKYGT 180
  181 KEEAITRGNC LEEDKEKASA EIKVLSNRLS ENRAKLEQLR GEYFNQLSHD PILYQFEQLN 240
  241 STRLGSDILT SFTMVSRVSK GYQDIFKILS DLSEAY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 1jv2B_
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [277-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSLNDKVVN DNIKKFRKVR RRAEKAKINA DSKIDDEQAD NLYLYFTEEV PQIFLKRESE  60
   61 NTLRYVIGKS NFVQALVEGK INYTNDILEY IREFRLIMDD ISQNYNVNFQ DAGVKSAVDS 120
  121 YKNYLGEYGE LAELEPAHPS ESLLRSLSEV TSFVNENA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [435-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKVLPPDAVE SEQDTNSDHI GTSGDLRNKL KEILSKLNIF SSRKDLVSLE KRFRSCESQV  60
   61 SLLENELKQK MDYKKLLDET EDEGTNSTAG NLTELLELMG SQSYCLDDIL DNYVYTICFQ 120
  121 RPMTEG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.16931544864195 bayes_pls_golite062009
protein binding 0.872890850602389 bayes_pls_golite062009
protein kinase activity 0.583206284003708 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.508369072880209 bayes_pls_golite062009
kinase activity 0.391568627986248 bayes_pls_golite062009
catalytic activity 0.282237710666423 bayes_pls_golite062009
monosaccharide binding 0.210030780379333 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.181223198260708 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [561-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIYQAEDKVD GKKVLIGRFK TSGFNVDLNM EKYAEHLKAT YDEKSDLISN LAAIQDDDGN  60
   61 MQHYVFGNLN ELNNGLVLEY ENGDQCWNGP RRSATVFVRC SDKFKIRSVH EATKCNYIFD 120
  121 VVGPLGCNKT FEYEPPKFNL SE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.88
Match: 1keoA
Description: Cation-dependent mannose 6-phosphate receptor, extracytoplasmic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle