| Protein: | GTB1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 702 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTB1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..702] | [1..702] |
|
|
2.0E-53 | [444..682] | [131..377] |
|
|
6.0E-51 | [444..683] | [259..513] |
|
|
1.0E-47 | [491..690] | [63..247] |
|
Region A: Residues: [1-276] |
1 11 21 31 41 51
| | | | | |
1 MVSMFSLFLL LIEQSPLVAS LQQSQRHIVG VPWEKQHLYD SNEPDLTKWH CLNHEDIVLD 60
61 ISQINDGVCD CPDGSDEPGS AACVEDIFKS VAEGGGKVNK YFYCDNKGFI PRYIRKSEVA 120
121 DGICDCCDCS DELLSGYELF DAGSNCSQLK NEFDIMASKE LSSYREGKEA LEELERKYGT 180
181 KEEAITRGNC LEEDKEKASA EIKVLSNRLS ENRAKLEQLR GEYFNQLSHD PILYQFEQLN 240
241 STRLGSDILT SFTMVSRVSK GYQDIFKILS DLSEAY
|
| Detection Method: |  |
| Confidence: | 21.522879 |
| Match: | 1jv2B_ |
| Description: | Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [277-434] |
1 11 21 31 41 51
| | | | | |
1 TPSLNDKVVN DNIKKFRKVR RRAEKAKINA DSKIDDEQAD NLYLYFTEEV PQIFLKRESE 60
61 NTLRYVIGKS NFVQALVEGK INYTNDILEY IREFRLIMDD ISQNYNVNFQ DAGVKSAVDS 120
121 YKNYLGEYGE LAELEPAHPS ESLLRSLSEV TSFVNENA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.517 | a.118.1 | ARM repeat |
| View | Download | 0.294 | a.26.1 | 4-helical cytokines |
| View | Download | 0.314 | a.118.9 | ENTH/VHS domain |
| View | Download | 0.435 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.517 | a.118.1 | ARM repeat |
| View | Download | 0.294 | a.26.1 | 4-helical cytokines |
| View | Download | 0.467 | a.24.4 | Hemerythrin |
| View | Download | 0.314 | a.118.9 | ENTH/VHS domain |
| View | Download | 0.435 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.467 | a.24.4 | Hemerythrin |
| View | Download | 0.280 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.279 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.271 | c.55.1 | Actin-like ATPase domain |
| View | Download | 0.268 | a.29.2 | Bromodomain |
| View | Download | 0.238 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.217 | a.118.8 | TPR-like |
| View | Download | 0.205 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.201 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
|
Region A: Residues: [435-560] |
1 11 21 31 41 51
| | | | | |
1 PKVLPPDAVE SEQDTNSDHI GTSGDLRNKL KEILSKLNIF SSRKDLVSLE KRFRSCESQV 60
61 SLLENELKQK MDYKKLLDET EDEGTNSTAG NLTELLELMG SQSYCLDDIL DNYVYTICFQ 120
121 RPMTEG
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.393 | 0.032 | endoplasmic reticulum | a.25.1 | Ferritin-like |
| View | Download | 0.542 | 0.010 | endoplasmic reticulum | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.580 | N/A | N/A | a.185.1 | Gametocyte protein Pfg27 |
| View | Download | 0.479 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.375 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.345 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.337 | N/A | N/A | a.152.1 | Antioxidant defence protein AhpD |
| View | Download | 0.328 | N/A | N/A | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.301 | N/A | N/A | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.300 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.280 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.274 | N/A | N/A | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.273 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.271 | N/A | N/A | c.26.2 | Adenine nucleotide alpha hydrolases-like |
| View | Download | 0.245 | N/A | N/A | a.7.8 | GAT domain |
| View | Download | 0.244 | N/A | N/A | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.239 | N/A | N/A | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.234 | N/A | N/A | a.1.2 | alpha-helical ferredoxin |
| View | Download | 0.230 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.224 | N/A | N/A | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.223 | N/A | N/A | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.221 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.219 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.217 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.215 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.209 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.209 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.207 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.207 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.205 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| Term | Confidence | Notes |
| binding | 1.16931544864195 | bayes_pls_golite062009 |
| protein binding | 0.872890850602389 | bayes_pls_golite062009 |
| protein kinase activity | 0.583206284003708 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.508369072880209 | bayes_pls_golite062009 |
| kinase activity | 0.391568627986248 | bayes_pls_golite062009 |
| catalytic activity | 0.282237710666423 | bayes_pls_golite062009 |
| monosaccharide binding | 0.210030780379333 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.181223198260708 | bayes_pls_golite062009 |
|
Region A: Residues: [561-702] |
1 11 21 31 41 51
| | | | | |
1 VIYQAEDKVD GKKVLIGRFK TSGFNVDLNM EKYAEHLKAT YDEKSDLISN LAAIQDDDGN 60
61 MQHYVFGNLN ELNNGLVLEY ENGDQCWNGP RRSATVFVRC SDKFKIRSVH EATKCNYIFD 120
121 VVGPLGCNKT FEYEPPKFNL SE
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| Detection Method: | |
| Confidence: | 7.88 |
| Match: | 1keoA |
| Description: | Cation-dependent mannose 6-phosphate receptor, extracytoplasmic domain |
Matching Structure (courtesy of the PDB): |
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