| Protein: | EKI1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 534 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EKI1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..534] | [1..534] |
|
|
2.0E-94 | [22..480] | [2..386] |
|
|
6.0E-92 | [54..474] | [68..449] |
|
|
6.0E-82 | [100..470] | [70..430] |
|
|
6.0E-80 | [94..480] | [65..412] |
|
Region A: Residues: [1-98] |
1 11 21 31 41 51
| | | | | |
1 MYTNYSLTSS DAMPRTYLVG TASPEMSKKK RQSANCDKPT RRVIHIIDTN EHSEVDLKNE 60
61 LPITCTNEDG EMTSSSWTSQ TANDFLKLAY VNAKLDPS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.613 | 0.869 | cytoplasm | b.55.1 | PH domain-like |
| View | Download | 0.499 | 0.869 | cytoplasm | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.592 | 0.869 | cytoplasm | b.55.1 | PH domain-like |
| View | Download | 0.464 | 0.869 | cytoplasm | b.55.1 | PH domain-like |
| View | Download | 0.428 | 0.869 | cytoplasm | b.101.1 | Ribonuclease domain of colicin E3 |
| View | Download | 0.402 | 0.869 | cytoplasm | d.102.1 | Regulatory factor Nef |
| View | Download | 0.324 | 0.869 | cytoplasm | b.1.2 | Fibronectin type III |
| View | Download | 0.322 | 0.869 | cytoplasm | d.93.1 | SH2 domain |
| View | Download | 0.311 | 0.869 | cytoplasm | b.87.1 | LexA/Signal peptidase |
| View | Download | 0.311 | 0.869 | cytoplasm | d.192.1 | YlxR-like |
| View | Download | 0.284 | 0.869 | cytoplasm | b.60.1 | Lipocalins |
| View | Download | 0.263 | 0.869 | cytoplasm | b.55.1 | PH domain-like |
| View | Download | 0.218 | 0.869 | cytoplasm | b.114.1 | N-utilization substance G protein NusG, insert domain |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 2.56238090010785 | bayes_pls_golite062009 |
| binding | 2.55015378442547 | bayes_pls_golite062009 |
| protein kinase activity | 2.44081222683977 | bayes_pls_golite062009 |
| kinase activity | 2.34459475289562 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.95139794143606 | bayes_pls_golite062009 |
| transferase activity | 1.80001061545783 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 1.55379052459468 | bayes_pls_golite062009 |
| lipid kinase activity | 1.3504796246251 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| choline kinase activity | 1.18757364210199 | bayes_pls_golite062009 |
| protein binding | 1.12583111976692 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 1.10484220525143 | bayes_pls_golite062009 |
| 1-phosphatidylinositol-3-kinase activity | 1.04034573968654 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 0.97254836668426 | bayes_pls_golite062009 |
| ethanolamine kinase activity | 0.68804237112665 | bayes_pls_golite062009 |
|
Region A: Residues: [99-178] |
1 11 21 31 41 51
| | | | | |
1 LPSQYFKQDI INVLQSLEIP GWSVPGSKES SLNKNLLTLT QIKGALTNVI YKIHYPNLPP 60
61 LLMRIFGDSI DSVIDREYEL
|
|
Region B: Residues: [192-205] |
1 11 21 31 41 51
| | | | | |
1 KLEGFFENGR FEKY
|
| Detection Method: | |
| Confidence: | 2.522879 |
| Match: | 1j7iA_ |
| Description: | Type IIIa 3',5"-aminoglycoside phosphotransferase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [179-191] |
1 11 21 31 41 51
| | | | | |
1 KVIARLSFYD LGP
|
|
Region B: Residues: [206-447] |
1 11 21 31 41 51
| | | | | |
1 IEGSRTSTQA DFIDRDTSIK IAKKLKELHC TVPLTHKEIT DQPSCWTTFD QWIKLIDSHK 60
61 EWVSNNVNIS ENLRCSSWNF FLKSFKNYKR WLYNDSAFTS KLLREDDKDS MINSGLKMVF 120
121 CHNDLQHGNL LFKSKGKDDI SVGDLTIIDF EYAGPNPVVF DLSNHLNEWM QDYNDVQSFK 180
181 SHIDKYPKEE DILVFAQSYI NHMNENHVKI ASQEVRILYN LIIEWRPCTQ LFWCLWALLQ 240
241 SG
|
| Detection Method: | |
| Confidence: | 2.522879 |
| Match: | 1j7iA_ |
| Description: | Type IIIa 3',5"-aminoglycoside phosphotransferase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [448-534] |
1 11 21 31 41 51
| | | | | |
1 RLPQRPLIEG EKLMSEKAGL GDETHLMEHK NKENGKYDCS EDDSFNYLGF CKEKMSVFWG 60
61 DLITLGVIDK DCPDIGKTDY LDTKLIF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.333 | a.118.1 | ARM repeat |
| View | Download | 0.389 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.361 | a.74.1 | Cyclin-like |
| View | Download | 0.363 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.397 | a.60.8 | HRDC-like |
| View | Download | 0.309 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.292 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.281 | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.260 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.248 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.228 | a.74.1 | Cyclin-like |
| View | Download | 0.227 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.223 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.210 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
