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View Structure Prediction Details

Protein: OCA6
Organism: Saccharomyces cerevisiae
Length: 224 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCA6.

Description E-value Query
Range
Subject
Range
gi|151942056 - gi|151942056|gb|EDN60412.1| oxidant-induced cell-cycle arrest [Saccharomyces cerevisiae YJM789]
OCA6_YEAST - Putative tyrosine-protein phosphatase OCA6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
gi|190404965 - gi|190404965|gb|EDV08232.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
OCA6 - Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a mode...
1.0E-51 [1..224] [1..224]
gi|162319572 - gi|162319572|gb|AAI56889.1| Protein tyrosine phosphatase, receptor type, U [synthetic construct]
gi|148698181, gi... - gi|2627027|dbj|BAA23475.1| Ftp-1 [Mus musculus], gi|148698181|gb|EDL30128.1| protein tyrosine phosph...
2.0E-36 [12..216] [981..1176]
gi|18860902, gi|... - gi|57209032|emb|CAI41222.1| protein tyrosine phosphatase, receptor type, K [Homo sapiens], gi|572083...
gi|114609259 - gi|114609259|ref|XP_001167740.1| PREDICTED: protein tyrosine phosphatase, receptor type, K isoform 9...
2.0E-36 [12..220] [989..1189]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-36 [12..216] [981..1176]

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Predicted Domain #1
Region A:
Residues: [1-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLVTPLQFS TVQPNLYRGS YPREINLPFL RTLRLKYILS LTPEPLSTDP LMVKFCEENN  60
   61 IKTIHIKCQS ERKADKTKPK IKRKKKTVPI EYDVVVRCVK FLIDKGHYPC YMHCTNGELI 120
  121 ISLVVACMRK FSYWSTVSIL NEFLVYNSSI NIHERNFIEN FNSEIEVDDL DIKDKVPWIT 180
  181 VRYIARTATE SKDELRVDDA NASEKVARVS SVSNSLPKLK FHSM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 1rpmA_
Description: Tyrosine phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 7.30669036331612 bayes_pls_golite062009
phosphatase activity 6.6585143972081 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.44546424348532 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.56007278295923 bayes_pls_golite062009
protein tyrosine phosphatase activity 5.3097342170423 bayes_pls_golite062009
hydrolase activity 4.08088661270715 bayes_pls_golite062009
transmembrane receptor protein phosphatase activity 2.94635032478625 bayes_pls_golite062009
transmembrane receptor protein tyrosine phosphatase activity 2.94635032478625 bayes_pls_golite062009
protein tyrosine/serine/threonine phosphatase activity 2.77531895423367 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.95004535887255 bayes_pls_golite062009
protein binding 1.2114562222518 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 1.1200449509328 bayes_pls_golite062009
catalytic activity 1.06283028154109 bayes_pls_golite062009
lipid phosphatase activity 1.05085928819585 bayes_pls_golite062009
binding 0.827427419667143 bayes_pls_golite062009
non-membrane spanning protein tyrosine phosphatase activity 0.724257798127697 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0776644624761281 bayes_pls_golite062009
kinase activity 0.0715870881653981 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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