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View Structure Prediction Details

Protein: DAS2
Organism: Saccharomyces cerevisiae
Length: 232 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAS2.

Description E-value Query
Range		 Subject
Range
UKL2_ARATH - Uridine kinase-like protein 2, chloroplastic OS=Arabidopsis thaliana GN=UKL2 PE=2 SV=1
 1.0E-49 [2..217] [54..279]
UCKL1_MOUSE - Uridine-cytidine kinase-like 1 OS=Mus musculus GN=Uckl1 PE=1 SV=1
 1.0E-47 [7..201] [95..304]
gi|151942008 - gi|151942008|gb|EDN60364.1| conserved protein [Saccharomyces cerevisiae YJM789]
DAS2_YEAST - Putative uridine kinase DAS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAS2 PE=1 S...
gi|207346850 - gi|207346850|gb|EDZ73218.1| YDR020Cp-like protein [Saccharomyces cerevisiae AWRI1631]
DAS2 - Putative protein of unknown function; non-essential gene identified in a screen for mutants with inc...
gi|190405006 - gi|190405006|gb|EDV08273.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
 3.0E-47 [1..232] [1..232]
gi|25287546 - pir||AD2321 phosphoribulokinase [imported] - Nostoc sp. (strain PCC 7120)
gi|17133258, gi|... - gi|17231615|ref|NP_488163.1| phosphoribulokinase [Nostoc sp. PCC 7120], gi|17133258|dbj|BAB75822.1| ...
 8.0E-47 [6..222] [4..226]
gi|8099163 - gi|8099163|dbj|BAA96253.1| phosphoribulokinase [Synechococcus elongatus PCC 7942]
 2.0E-46 [5..221] [2..224]
CE20700 - status:Confirmed UniProt:Q9U3I7 protein_id:CAA93462.1
 3.0E-46 [2..213] [95..323]

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Predicted Domain #1
Region A:
Residues: [1-232] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRKAVEEKR IVISIGGGHA TGVGAIALDL QNTFKSLYNS INIRVINLDN MIEGNIKSYN  60
   61 NNDYDFDNIL NLVYEKHAVT SQNDMIQHDY EDPIDLIIVC GCYALYDKRI NEISQLKVFL 120
  121 DSDADKRLIS LIKKKNVGSN EQLAQLITEY MDHLRPEMQQ YIEPTRTFAD LIIPSTNENL 180
  181 GRAVLVDGIV KAIEDTKSQI EGNNTNNKIR PRLWDFEAET MDLEKDRYYD LS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1a7j__
Description: Phosphoribulokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.05253348982328 bayes_pls_golite062009
nucleic acid binding 1.60768715809391 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
RNA helicase activity 1.02424782546779 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
RNA-dependent ATPase activity 0.95986988363392 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.94128341275411 bayes_pls_golite062009
hydrolase activity 0.533811513387322 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle