YRC Public Data Repository - Protein Structure Prediction

Protein:	YDL177C
Organism:	Saccharomyces cerevisiae
Length:	170 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDL177C.

Description	E-value	Query Range	Subject Range
YDL177C - Putative protein of unknown function; similar to the mouse IMPACT gene; YDL177C is not an essential ... YD177_YEAST - IMPACT family member YDL177C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDL177C PE=...	3.0E-55	[1..170]	[1..170]
gi\|16801721 - gi\|16801721\|ref\|NP_471989.1\| hypothetical protein lin2660 [Listeria innocua Clip11262] gi\|25303440, gi\|... - pir\|\|AF1764 conserved hypothetical protein homolog lin2660 [imported] - Listeria innocua (strain Cli...	4.0E-40	[45..167]	[1..128]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-40	[45..167]	[1..128]
YVYE_BACSU - IMPACT family member yvyE OS=Bacillus subtilis GN=yvyE PE=3 SV=2 gi\|221315829 - gi\|221315829\|ref\|ZP_03597634.1\| hypothetical protein BsubsN3_19122 [Bacillus subtilis subsp. subtili... gi\|221320744 - gi\|221320744\|ref\|ZP_03602038.1\| hypothetical protein BsubsJ_19085 [Bacillus subtilis subsp. subtilis... YVYE_BACSU - IMPACT family member YvyE OS=Bacillus subtilis (strain 168) GN=yvyE PE=3 SV=2 gi\|221325029 - gi\|221325029\|ref\|ZP_03606323.1\| hypothetical protein BsubsS_19241 [Bacillus subtilis subsp. subtilis...	2.0E-39	[45..167]	[1..128]
gi\|224503243 - gi\|224503243\|ref\|ZP_03671550.1\| hypothetical protein LmonFR_12133 [Listeria monocytogenes FSL R2-561... gi\|25303439, gi\|... - pir\|\|AD1389 conserved hypothetical proteins homolog lmo2516 [imported] - Listeria monocytogenes (str... gi\|16804554 - gi\|16804554\|ref\|NP_466039.1\| hypothetical protein lmo2516 [Listeria monocytogenes EGD-e]	4.0E-39	[45..167]	[1..128]
gi\|25303432 - pir\|\|F84103 hypothetical protein BH3630 [imported] - Bacillus halodurans (strain C-125) gi\|10176254, gi\|... - gi\|15616192\|ref\|NP_244497.1\| hypothetical protein BH3630 [Bacillus halodurans C-125], gi\|10176254\|db...	7.0E-39	[45..167]	[1..128]
gi\|4996357 - gi\|4996357\|dbj\|BAA78421.1\| unnamed protein product [Xenopus borealis]	8.0E-39	[16..169]	[171..289]
gi\|116515439, gi... - gi\|116515439\|ref\|YP_817421.1\| hypothetical protein SPD_2036 [Streptococcus pneumoniae D39], gi\|11607... gi\|15459719, gi\|... - gi\|15904055\|ref\|NP_359605.1\| hypothetical protein spr2014 [Streptococcus pneumoniae R6], gi\|15459719... gi\|25303437 - pir\|\|C98123 conserved hypothetical protein spr2014 [imported] - Streptococcus pneumoniae (strain R6) gi\|147923289, gi... - gi\|148984512\|ref\|ZP_01817800.1\| hypothetical protein CGSSp3BS71_10673 [Streptococcus pneumoniae SP3-... gi\|221232910, gi... - gi\|221232910\|ref\|YP_002512064.1\| hypothetical protein SPN23F_22420 [Streptococcus pneumoniae ATCC 70... gi\|225857778, gi... - gi\|225857778\|ref\|YP_002739289.1\| hypothetical protein SPP_2262 [Streptococcus pneumoniae P1031], gi\|... gi\|168494030, gi... - gi\|183575911\|gb\|EDT96439.1\| conserved hypothetical protein [Streptococcus pneumoniae CDC3059-06], gi... gi\|194397335, gi... - gi\|194397335\|ref\|YP_002038805.1\| conserved hypothetical protein [Streptococcus pneumoniae G54], gi\|1... gi\|183569909, gi... - gi\|183569909\|gb\|EDT90437.1\| conserved hypothetical protein [Streptococcus pneumoniae CDC1087-00], gi... gi\|183574018, gi... - gi\|183574018\|gb\|EDT94546.1\| conserved hypothetical protein [Streptococcus pneumoniae CDC0288-04], gi... gi\|172042422, gi... - gi\|172042422\|gb\|EDT50468.1\| conserved hypothetical protein [Streptococcus pneumoniae CDC1873-00], gi... gi\|147930806, gi... - gi\|149020128\|ref\|ZP_01835102.1\| hypothetical protein CGSSp23BS72_08834 [Streptococcus pneumoniae SP2... gi\|149007747, gi... - gi\|149007747\|ref\|ZP_01831356.1\| hypothetical protein CGSSp18BS74_00225 [Streptococcus pneumoniae SP1...	2.0E-38	[47..167]	[1..126]
gi\|11494012 - gi\|11494012\|gb\|AAG35736.1\|AF208694_1 IMPACT [Homo sapiens]	2.0E-38	[17..168]	[178..294]
gi\|14973721, gi\|... - gi\|66878383\|ref\|ZP_00403866.1\| COG1739: Uncharacterized conserved protein [Streptococcus pneumoniae ... gi\|25303433 - pir\|\|C95258 conserved hypothetical protein SP2209 [imported] - Streptococcus pneumoniae (strain TIGR...	2.0E-38	[47..167]	[1..126]

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Predicted Domain #1

Region A:
Residues: [1-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKNVGKLVK IWNESEVLVD RKSKFQARCC PLQNQKDIPS ILQELTQNNK SVSKASHMHM  60
   61 YAWRTAEVSN NLHLQQEQKK KGNKANKSNN SHVNKSRNIT VQPKNIEQGC ADCGEAGAGQ 120
  121 RLLTLLERAN IFNVLVIVTR WYGGTPLGSS RFRHISTCAV ETLKKGGFLP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	60.744727
Match:	PF01205
Description:	Uncharacterized protein family UPF0029

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [58-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHMYAWRTAE VSNNLHLQQE QKKKGNKANK SNNSHVNKSR NITVQPKNIE QGCADCGEAG  60
   61 AGQRLLTLLE RANIFNVLVI VTRWYGGTPL GSSRFRHIST CAVETLKKGG FLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.0
Match:	2cveA
Description:	Crystal structure of a conserved hypothetical protein TT1547 from thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.112026646106867	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: