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View Structure Prediction Details

Protein: AIR2
Organism: Saccharomyces cerevisiae
Length: 344 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIR2.

Description E-value Query
Range
Subject
Range
AIR1 - Zinc knuckle protein, involved in nuclear RNA processing and degradation as a component of the TRAMP...
AIR1_YEAST - Protein AIR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AIR1 PE=1 SV=1
gi|151943084 - gi|151943084|gb|EDN61419.1| arginine methyltransferase-interacting ring finger protein [Saccharomyce...
323.0 [0..4] [339..12]
gi|4324757 - gi|4324757|gb|AAD17021.1| gag-pol polyprotein [Human immunodeficiency virus type 1]
310.0 [0..3] [178..291]
POL_HV1B9 - Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (strain 89.6) GN=gag-po...
310.0 [0..3] [159..294]
POL_HV1JR - Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) GN=gag-...
308.0 [0..3] [170..294]

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Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKNTAPFVV DTAPTTPPDK LVAPSIEEVN SNPNELRALR GQGRYFGVSD DDKDAIKEAA  60
   61 PKCNNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.09691
Match: 1bajA
Description: HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [67-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQRGHLKKDC PHIICSYCGA TDDHYSRHCP KAIQCSKCDE VGHYRSQCPH KWKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.221849
Match: 1aafA
Description: NUCLEOCAPSID ZINC FINGERS DETECTED IN RETROVIRUSES: EXAFS STUDIES ON INTACT VIRUSES AND THE SOLUTION-STATE STRUCTURE OF THE NUCLEOCAPSID PROTEIN FROM HIV-1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [121-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQCTLCKSKK HSKERCPSIW RAYILVDDNE KAKPKVLPFH TIYCYNCGGK GH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.621 g.13.1 Crambin-like
View Download 0.605 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.522 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.522 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.481 a.60.2 RuvA domain 2-like
View Download 0.469 d.80.1 Tautomerase/MIF
View Download 0.371 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.360 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.299 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.298 d.254.1 Description not found.
View Download 0.291 a.159.4 Description not found.
View Download 0.283 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.283 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.277 d.40.1 CI-2 family of serine protease inhibitors
View Download 0.268 d.40.1 CI-2 family of serine protease inhibitors

Predicted Domain #4
Region A:
Residues: [173-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGDDCKEKRS SRVPNEDGSA FTGSNLSVEL KQEYYRHMNR NSDENEDYQF SESIYDEDPL  60
   61 PRPSHKRHSQ NDHSHSGRNK RRASNFHPPP YQKSNVIQPT IRGETL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.493 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.385 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.355 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.355 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.263 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.243 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.203 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.203 N/A N/A d.58.42 N-utilization substance G protein NusG, N-terminal domain

Predicted Domain #5
Region A:
Residues: [279-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLNNNISKNS RYQNTKVNVS SISENMYGSR YNPSTYVDNN SISNSSNYRN YNSYQPYRSG  60
   61 TLGKRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.372 g.18.1 Complement control module/SCR domain
View Download 0.339 d.50.3 PI-Pfui intein middle domain
View Download 0.332 d.344.1 Description not found.
View Download 0.327 d.17.3 Disulfide bond isomerase, DsbC, N-terminal domain
View Download 0.320 d.50.3 PI-Pfui intein middle domain
View Download 0.299 d.17.3 Disulfide bond isomerase, DsbC, N-terminal domain
View Download 0.273 g.39.1 Glucocorticoid receptor-like (DNA-binding domain)
View Download 0.251 d.50.1 dsRNA-binding domain-like
View Download 0.235 a.4.1 Homeodomain-like
View Download 0.228 d.50.1 dsRNA-binding domain-like
View Download 0.228 g.41.17 Description not found.
View Download 0.222 d.19.1 MHC antigen-recognition domain
View Download 0.213 a.39.1 EF-hand


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