| Protein: | OSH2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1283 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OSH2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1283] | [1..1283] |
|
|
0.0 | [1..1283] | [1..1190] |
|
|
0.0 | [8..1283] | [15..1310] |
|
|
0.0 | [529..1278] | [108..824] |
|
|
0.0 | [639..1283] | [89..719] |
|
|
0.0 | [628..1283] | [112..752] |
|
Region A: Residues: [1-135] |
1 11 21 31 41 51
| | | | | |
1 MSREDLSIAE DLNQVSKPLL KVKLLEVLGQ GDFKHLKALV DNEFQPKDDP SVQQVLNLIL 60
61 HYAVQVAPIL LIKEIVAHWV DQVGDEKSSS KSDDGIHLDL NYQDENGNTP LHLAAAQSRS 120
121 DVISFLLSQK SINDC
|
| Detection Method: |  |
| Confidence: | 43.154902 |
| Match: | 1k1aA_ |
| Description: | bcl-3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.03195138036959 | bayes_pls_golite062009 |
| protein binding | 1.6716587413544 | bayes_pls_golite062009 |
| transporter activity | 1.19000052859754 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.02570255606772 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.581121752453591 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.428839878681413 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.240863793118641 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.16792752511707 | bayes_pls_golite062009 |
|
Region A: Residues: [136-273] |
1 11 21 31 41 51
| | | | | |
1 VKNKAHQQPL DMCKDLNVAQ MIQLKRDDYF LETVHSLRAA MNKRDFSKLD SIWKNPRNLN 60
61 LLDINGIDPE TGTTLLYEYS QKKDIEMCQW LLKHGAEATV KDGKGRSPLD LVKNIKLPAK 120
121 PSNNVTPEIK LKNLLEKN
|
| Detection Method: | |
| Confidence: | 43.154902 |
| Match: | 1k1aA_ |
| Description: | bcl-3 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [274-401] |
1 11 21 31 41 51
| | | | | |
1 LREQAIVHED VASSKPPTYK GFLKKWTNFA HGYKLRWFIL SGDGNLSYYK DQSHVDRPRG 60
61 TLKVSTCRLH IDSSEKLNFE LLGGITGTTR WRLKGNHPIE TTRWVNAIQS AIRFAKDKEI 120
121 LNKKKAVP
|
| Detection Method: | |
| Confidence: | 14.78 |
| Match: | 1faoA |
| Description: | Dual adaptor of phosphotyrosine and 3-phosphoinositides DAPP1/PHISH |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [402-542] |
1 11 21 31 41 51
| | | | | |
1 PSLALKNKSP ALISHSKTQG SLPEASQYYQ HTLHKEVIQP SSVSLYRRPS NNLSVVSSEI 60
61 QLNDNLTESG KRFVSKMIEN RLDGSKTPVG VHTGSALQRV RSSNTLKSNR SMQSGSGVAS 120
121 PIDKVPNGAN LSQSNTTTGS T
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.357 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.536 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.388 | a.118.8 | TPR-like |
| View | Download | 0.442 | d.58.29 | Adenylyl and guanylyl cyclase catalytic domain |
| View | Download | 0.426 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.460 | d.58.22 | TRADD, N-terminal domain |
| View | Download | 0.385 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.382 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.355 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.347 | d.52.2 | GMP synthetase C-terminal dimerisation domain |
| View | Download | 0.347 | d.13.1 | HIT-like |
| View | Download | 0.346 | c.26.1 | Nucleotidylyl transferase |
| View | Download | 0.341 | d.109.2 | C-terminal, gelsolin-like domain of Sec23/24 |
| View | Download | 0.332 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.323 | a.26.1 | 4-helical cytokines |
| View | Download | 0.323 | d.58.13 | Anticodon-binding domain of PheRS |
| View | Download | 0.299 | d.58.19 | Bacterial exopeptidase dimerisation domain |
| View | Download | 0.298 | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.297 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.292 | d.52.6 | BolA-like |
| View | Download | 0.277 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.272 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.263 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.254 | c.50.1 | Macro domain-like |
| View | Download | 0.251 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.246 | d.21.1 | Diaminopimelate epimerase-like |
| View | Download | 0.246 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.244 | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.240 | d.110.5 | Pheromone-binding domain of LuxR-like quorum-sensing transcription factors |
| View | Download | 0.233 | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.231 | d.15.6 | Superantigen toxins, C-terminal domain |
| View | Download | 0.224 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.220 | d.93.1 | SH2 domain |
| View | Download | 0.220 | c.23.10 | SGHN hydrolase |
| View | Download | 0.215 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.207 | d.52.7 | Ribosome-binding factor A, RbfA |
| View | Download | 0.204 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.203 | c.23.1 | CheY-like |
|
Region A: Residues: [543-888] |
1 11 21 31 41 51
| | | | | |
1 ASLSDNNYID NFEGDEANSD DEEEDLGINF DRDEEYIKAQ YGPYKEKLDM YEQAISIELS 60
61 SLIELIEQEE PSPEVWLTIK KSLINTSTIF GKLKDLTYKR DKRLVDMVSK QGDVNNVWVQ 120
121 SVKELEMELS NKTERLASID KERRGLKKIL HKKLLESHAT AGNKESLEND KEQESDTTAS 180
181 TLGQIAKFIS ATKEEDEASD ADEFYDAAEL VDEVTELTEA HPEISTAAAP KHAPPPVPNE 240
241 TDNDSQYVQD EKSKIESNVE KTSQKFEKQN NLVTEDEPKT DQSLKNFKAE DKESQVKEKT 300
301 KEIASSVIGE KTIVAVTTVQ KRKEEYLLKE GSYLGYEDGI RKRLSM
|
| Detection Method: | |
| Confidence: | 3.69897 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| sterol binding | 4.18891468109664 | bayes_pls_golite062009 |
| oxysterol binding | 3.82897024895265 | bayes_pls_golite062009 |
| 3.02967613614595 | bayes_pls_golite062009 | |
| steroid binding | 2.54679035876403 | bayes_pls_golite062009 |
| phosphoinositide binding | 2.2725849852584 | bayes_pls_golite062009 |
| phospholipid binding | 2.08170907241909 | bayes_pls_golite062009 |
| binding | 1.96043183869108 | bayes_pls_golite062009 |
| lipid binding | 1.8520231230392 | bayes_pls_golite062009 |
| cholesterol binding | 0.644339278395346 | bayes_pls_golite062009 |
|
Region A: Residues: [889-1283] |
1 11 21 31 41 51
| | | | | |
1 DKDDRPKISL WAVLKSMVGK DMTRMTLPVT FNEPTSLLQR VAEDLEYSEL LDQAATFEDS 60
61 TLRTLYVAAF TASSYASTTK RVAKPFNPLL GETFEYSRPD KQYRFFTEQV SHHPPISATW 120
121 TESPRWDFWG ESFVDTKFNG RSFNVKHLGL WHIKLRPNDN EKEELYTWKK PNNTVIGILI 180
181 GNPQVDNHGE VNVVNHTTGD HCKLYFKARG WRSSGAYEIT GEVYNKKKQK VWILGGHWNE 240
241 AIFAKKVVKD GDLSLEKTRT AASAGNGPTD DGTKFLIWKA NDRPEEPFNL TPFAITLNAP 300
301 QPHLLPWLPP TDTRLRPDQR AMEDGRYDEA GDEKFRVEEK QRAARRKREE NNLEYHPQWF 360
361 VRDTHPITKA KYWRYTGKYW VKRRDHDLKD CGDIF
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
