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View Structure Prediction Details

Protein: TAF2
Organism: Saccharomyces cerevisiae
Length: 1407 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF2.

Description E-value Query
Range
Subject
Range
TAF2 - TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation
TAF2_YEAST - Transcription initiation factor TFIID subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..1407] [1..1407]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [1..1407] [4..1410]
taf2 - TATA-binding protein associated factor Taf2
gi|19114243 - gi|19114243|ref|NP_593331.1| hypothetical protein SPAC3A12.05c [Schizosaccharomyces pombe 972h-]
0.0 [18..1334] [2..1163]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [131..1334] [5..1097]
gi|14165178 - gi|14165178|gb|AAK55416.1|AF378117_1 aminopeptidase N [Aedes aegypti]
0.0 [136..844] [7..668]
ANPEP - alanyl (membrane) aminopeptidase
0.0 [249..848] [160..710]
gi|7158844 - gi|7158844|gb|AAF37560.1|AF217250_1 aminopeptidase 3 [Helicoverpa punctigera]
0.0 [233..845] [128..702]

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Predicted Domain #1
Region A:
Residues: [1-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSFSKNATP RAIVSESSTL HEMKFRNFRV AHEKISLDID LATHCITGSA TIIIIPLIQN  60
   61 LEYVTFDCKE MTIKDVLVEN RRCDQFIHDD PLQTNLNGLT SQNVLYSDNS IEQSHFLRSK 120
  121 FASLNEYPET DSKSQLTIKI PSSIKISLED ANALSNYTPI TPSIKTTPGF QESVFTPITL 180
  181 QIEYEIRNPK SGIKFDTVYA DKPWLWNVYT SNGEICSSAS YWVPCVDLLD EKSTWELEFS 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.15
Match: 1h19A
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [241-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPRLVKNIGT SKLIGQNGEE SEKEKEDTPE HDEEEEGKPA RVIKDEDKDS NLKNDEEGKN  60
   61 SKSKDAQDND EEEEEGESDE EEEEGEEERR NIEESNNPSL RDVIVCCSEY SNIKELPHPI 120
  121 DLTKKKCIFQ IINPVAPHHI GWAIGAF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [388-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSWSLPLISP PSVDAEDEVE EDKLRENVVD NVNDTMDDDI GSDIIPIQIF TLPTQETDEL  60
   61 TVINSTVVCQ KIIDFYSKEF GSYPFTCYSM VFLPTAPSKH MDFAALGICN TRLLYPLEVI 120
  121 DKAFSTTNEL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [518-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AWALANQWSC VNITPLDMND YWCCLGIAGY MVFQVTKKLM GNNTYKYQLK RNSEAIVEQD  60
   61 FEKPPIGSTF TGSSRPISWS SKDLSFIQLK APMILHILDR RMTKTERSFG MSRVLPKIFL 120
  121 QAMSGDLPNN SLTSSHFQHV CERVNKSKLE NFFNEWVYGS GVPILRVTQR FN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [690-789]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKRMVIELGI RQVQDEELGH EKVVGEEGFF KSALDHLEHP DLNRTECFTG SMTIRIHEHD  60
   61 GTPYEHIVEI KDTFTKIDIQ YNTKYRRLRK RGGGANDENG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.0
Match: 1hs6A_
Description: Leukotriene A4 hydrolase C-terminal domain; Leukotriene A4 hydrolase N-terminal domain; Leukotriene A4 hydrolase catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [790-951]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VENNNEEKPI VVDVNCLGNV YMSPEECSRF SLTEFNRTSE SNELLKQNEA FEWIRIDSDL  60
   61 EWICQMHINQ PDYMFSSQLR QDGDIEAQLE AIRYYEDVVV NGGVKSLVYS SILFRTAIDE 120
  121 RYFFGIRLAA CEALSKYVYD PDFTGGVKHL IQIFQILFCL ED

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [952-1407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNIPKSNNFE NPKLYFLQCN IPKYLAKVKN ENGKCPKLVK QFLLDILVYN ENGENKYSDD  60
   61 AYVRSLIENV VKVALNEYKD KAYMEKVKTQ LLRYENLVNW LSSYESLIKT TIMYAKYKLH 120
  121 KVGAYDFTEL TGMIMHTLTL GINNGDISRE SFQNEFLMVL KIMLLEGGLK NKDALVLFTE 180
  181 ILCFHEDSYI RDKSVDVLSE CVNLVVMDGS LDTISDDIKS SVQSVHNEVK NIKSEDDIEL 240
  241 FLSGHYVDDM KIKIEKIGRQ NISGLIQICR DMFKGYSPLK ILLWDVLNLP VLSLYQRKQI 300
  301 HDLVRVMYTL INSFVVRLET PRERRLVAKM NSNEEGKLDI VIKRESILKV HIKKEVTSTV 360
  361 EAPKKANKIK ISLKGDKPVR KVEKQIVKPK VTSKQRKVKS HVNRMGSLPL RFVKIQQQPR 420
  421 VMVHLSSVPY SQFVQITKVT SRSFMVKIRT KNDAKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle