YRC Public Data Repository - Protein Structure Prediction

Protein:	ILV6
Organism:	Saccharomyces cerevisiae
Length:	309 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ILV6.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..309]	[1..309]
ILV6_YEAST - Acetolactate synthase small subunit, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 /... ILV6 - Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino ...	0.0	[1..309]	[1..309]
gi\|1870125 - gi\|1870125\|emb\|CAB06790.1\| unknown [Saccharomyces pastorianus]	0.0	[1..309]	[1..309]
gi\|16565968 - gi\|16565968\|gb\|AAL26320.1\| acetolactate synthase small-subunit precursor-like protein [Magnaporthe g... gi\|38102628, gi\|... - gi\|39973499\|ref\|XP_368140.1\| conserved hypothetical protein [Magnaporthe grisea 70-15], gb\|EAA49446....	0.0	[3..309]	[4..316]
SPBC14C8.04 - acetolactate synthase regulatory unit ILV6_SCHPO - Probable acetolactate synthase small subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...	2.0E-77	[21..282]	[14..266]
gi\|7436727 - gi\|7436727\|pir\|\|S74358 acetolactate synthase ilvN - Synechocystis sp. (strain PCC 6803) gi\|16331478, gi\|... - gi\|16331478\|ref\|NP_442206.1\| acetolactate synthase 3 regulatory subunit [Synechocystis sp. PCC 6803]...	2.0E-59	[74..296]	[15..187]
ILVH1_ARATH - Acetolactate synthase small subunit 1, chloroplastic OS=Arabidopsis thaliana GN=VAT1 PE=1 SV=1	1.0E-56	[39..285]	[46..233]

Back

Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSLLQSGH RRVVASSCAT MVRCSSSSTS ALAYKQMHRH ATRPPLPTLD TPSWNANSAV  60
   61 SSIIYETPAP SRQPRKQHVL NCLVQNEPGV LSRVSGTLAA RGFNIDSLVV CNTEVKDLSR 120
  121 MTIVLQGQDG VVEQARRQIE DLVPVYAVLD YTNSEIIKRE LVMARISLLG TEYFEDLLLH 180
  181 HHTSTNAGAA

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	10.87
Match:	1in9A
Description:	No description for 1in9A was found.

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	14.1096734416761	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	12.4176994384119	bayes_pls_golite062009
transcription regulator activity	1.94365770896971	bayes_pls_golite062009
binding	1.29694755595984	bayes_pls_golite062009
nucleic acid binding	1.1911993852748	bayes_pls_golite062009
DNA binding	1.11572529990201	bayes_pls_golite062009
catalytic activity	0.645256181736122	bayes_pls_golite062009
transcription factor activity	0.595085179690602	bayes_pls_golite062009
protein binding	0.319036476490264	bayes_pls_golite062009
transcription repressor activity	0.11276971754733	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [191-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSQELVAEIR EKQFHPANLP ASEVLRLKHE HLNDITNLTN NFGGRVVDIS ETSCIVELSA  60
   61 KPTRISAFLK LVEPFGVLEC ARSGMMALPR TPLKTSTEEA ADEDEKISEI VDISQLPPG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: