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View Structure Prediction Details

Protein: ILV6
Organism: Saccharomyces cerevisiae
Length: 309 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ILV6.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..309] [1..309]
ILV6_YEAST - Acetolactate synthase small subunit, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 /...
ILV6 - Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino ...
0.0 [1..309] [1..309]
gi|1870125 - gi|1870125|emb|CAB06790.1| unknown [Saccharomyces pastorianus]
0.0 [1..309] [1..309]
gi|16565968 - gi|16565968|gb|AAL26320.1| acetolactate synthase small-subunit precursor-like protein [Magnaporthe g...
gi|38102628, gi|... - gi|39973499|ref|XP_368140.1| conserved hypothetical protein [Magnaporthe grisea 70-15], gb|EAA49446....
0.0 [3..309] [4..316]
SPBC14C8.04 - acetolactate synthase regulatory unit
ILV6_SCHPO - Probable acetolactate synthase small subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
2.0E-77 [21..282] [14..266]
gi|7436727 - gi|7436727|pir||S74358 acetolactate synthase ilvN - Synechocystis sp. (strain PCC 6803)
gi|16331478, gi|... - gi|16331478|ref|NP_442206.1| acetolactate synthase 3 regulatory subunit [Synechocystis sp. PCC 6803]...
2.0E-59 [74..296] [15..187]
ILVH1_ARATH - Acetolactate synthase small subunit 1, chloroplastic OS=Arabidopsis thaliana GN=VAT1 PE=1 SV=1
1.0E-56 [39..285] [46..233]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSLLQSGH RRVVASSCAT MVRCSSSSTS ALAYKQMHRH ATRPPLPTLD TPSWNANSAV  60
   61 SSIIYETPAP SRQPRKQHVL NCLVQNEPGV LSRVSGTLAA RGFNIDSLVV CNTEVKDLSR 120
  121 MTIVLQGQDG VVEQARRQIE DLVPVYAVLD YTNSEIIKRE LVMARISLLG TEYFEDLLLH 180
  181 HHTSTNAGAA 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.87
Match: 1in9A
Description: No description for 1in9A was found.

Predicted functions:

Term Confidence Notes
acetolactate synthase activity 14.1096734416761 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 12.4176994384119 bayes_pls_golite062009
transcription regulator activity 1.94365770896971 bayes_pls_golite062009
binding 1.29694755595984 bayes_pls_golite062009
nucleic acid binding 1.1911993852748 bayes_pls_golite062009
DNA binding 1.11572529990201 bayes_pls_golite062009
catalytic activity 0.645256181736122 bayes_pls_golite062009
transcription factor activity 0.595085179690602 bayes_pls_golite062009
protein binding 0.319036476490264 bayes_pls_golite062009
transcription repressor activity 0.11276971754733 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [191-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSQELVAEIR EKQFHPANLP ASEVLRLKHE HLNDITNLTN NFGGRVVDIS ETSCIVELSA  60
   61 KPTRISAFLK LVEPFGVLEC ARSGMMALPR TPLKTSTEEA ADEDEKISEI VDISQLPPG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.571 0.103 acetolactate synthase activity d.58.5 GlnB-like
View Download 0.571 0.077 acetolactate synthase activity d.58.3 Protease propeptides/inhibitors
View Download 0.478 0.038 acetolactate synthase activity d.198.1 Type III secretory system chaperone
View Download 0.695 0.023 acetolactate synthase activity d.58.10 Acylphosphatase-like
View Download 0.488 0.016 acetolactate synthase activity d.112.1 Phoshotransferase/anion transport protein
View Download 0.477 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.393 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.392 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.381 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.368 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.366 N/A N/A d.95.2 Homing endonucleases
View Download 0.365 N/A N/A d.58.11 EF-G/eEF-2 domains III and V
View Download 0.363 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.345 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.292 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.284 N/A N/A d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.281 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.278 N/A N/A d.198.2 Arp2/3 complex subunits
View Download 0.271 N/A N/A d.79.3 L30e-like
View Download 0.264 N/A N/A d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.260 N/A N/A d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.236 N/A N/A d.58.12 eEF-1beta-like
View Download 0.235 N/A N/A c.3.1 FAD/NAD(P)-binding domain
View Download 0.233 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.226 N/A N/A d.141.1 Ribosomal protein L6
View Download 0.222 N/A N/A c.23.1 CheY-like
View Download 0.219 N/A N/A d.68.3 SirA-like
View Download 0.217 N/A N/A d.58.17 Metal-binding domain
View Download 0.216 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.215 N/A N/A d.58.47 Hypothetical protein VC0424
View Download 0.213 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.210 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.209 N/A N/A d.58.24 CheY-binding domain of CheA


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle